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Biomedical subjects

W H Riege

Publications and source records attributed to W H Riege.

52 records · Page 3Linked to original sources
PubMed1980

Autonomic responsivity during recognition memory processing in three age groups.

Thirty male volunteers in the age groups of young (18-34 years), middle-aged (35-54 years), and old (55-72 years) performed a recurrent recognition task of eight emotional and eight neutral words embedded in balanced 50-word lists while their electrodermal (EDR), heart rate (HR), and recognition responses were recorded. During testing, two hours and again one week following presentation of the 16 words, no marked differences among age groups were observed in EDR, but HR responses were lower in the old than in the young group. The old adopted high signal detection decision criteria for emotional words, which accounted for their lower recognition of emotional words in one measure. The old were as proficient as the young in recognition of neutral words. More emotional words were correctly recognized when a person's responsivity in HR and EDR was high, but this correlation was dissociated in the old. Heart rate changes but not EDR reflected a reduced responsivity in the old. The results place in question the use of peripheral autonomic measures as an index to memory processing.

Adult↗
PubMed1980

Recognition memory for emotional words: a comparative study of young, middle-aged and older persons.

Emotional and neutral words were used to compare old, middle-aged, and young groups in their recognition memory at two hours and at one week following learning. The old retrieved fewer emotionally charged words than younger groups, while they were equally proficient in the recognition of neutral words. All groups made more correct and more false recognitions of emotional words than of neutral words. Based on discriminability measures, the emotional value of words induced a greater recognition difference at one week than at two hours. The old were less willing to guess than younger persons, adopting high decision criteria especially for emotional words during the two-hour test. The results were interpreted that the elderly are less responsive to emotional words or, alternatively, adopt more stringent recognition criteria for such words.

Adolescent↗
PubMed1976

Memory performance after flurothyl treatment in rainbow trout.

Fingerling rainbow trout (N = 436) were trained in one trial with brief electric shock (2.0 V/cm) to suppress their spontaneous upstream swimming into a quiet well. Memory retention one day later was not influenced by the temperature at which they had been acclimated, trained and tested (10 degrees C, 15 degrees C or 20 degrees C). When exposed 4 min after training for 2 min, to a flurothyl solution (10, 25, 50, 100 or 200 mul/l) trout convulsed and overturned. The onset of overturn was concentration- and temperature-dependent. Flurothyl altered the one-day retention of avoidance behavior; low concentrations enhanced, whereas high concentrations impaired. Memory-enhancing low concentrations of flurothyl, applied after post-training amnesic treatment with carbon dioxide, reversed the carbon dioxide amnesia.

Animals↗
PubMedDate not supplied

Cognitive and brain imaging measures of Alzheimer's disease.

Diagnosis of Alzheimer's disease (AD) during life relies upon clinical and neurobehavioral symptoms but is presumptive without microscopic verification of neuropathology. Studies in this review observed considerable heterogeneity in AD symptoms and did not agree on how to detect the earliest symptoms. Problems exist in diagnosis. Differences in symptoms and diagnosis result from how AD is defined neurobehaviorally and on the model used for description. The studies reviewed have been considered under three basic models: A severity (staging) model; a heterogeneity (subtyping) model; and an information processing model. Differences in model intent have resulted in differences in disease description. Brain imaging measures have not invalidated models but add the neural substrate needed to examine correlation of measures within each model.

Aged↗
PubMedDate not supplied

Age and alcoholism: independent memory decrements.

Similarities and differences in performances on 18 verbal and nonverbal memory tasks were studied in young and old alcoholics and in young and old controls as test of hypotheses postulating that cognitive decrements from alcoholism either mimic "premature aging," are "age sensitive," or are "independent" from those of normal aging. Young and old alcoholics were matched in length and rate of heavy drinking and were also equated with their controls in age, education, and vocabulary. The multivariate memory and decision data, when converted to independent factor scores, separated alcoholic from control groups on a factor reflecting memory for auditorily presented information. This was independent from factor scores affected mainly by age, such as memory for visuospatial items or decision bias. Age and alcoholism produced overlapping but distinctly different profiles of memory impairments. Decrements in young alcoholics did not resemble those of aging nor did old alcoholics surpass old controls in any but one factor, so that neither the premature aging nor the age sensitivity hypothesis were invariably supported.

Adult↗