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Biomedical subjects

W H Riley

Publications and source records attributed to W H Riley.

4 recordsLinked to original sources
PubMed1987

Cholera after the consumption of raw oysters. A case report.

In August 1986, a 76-year-old woman in Miami, Florida, developed profuse watery diarrhea and abdominal cramps. Two and four days before the onset of her illness, she had eaten six raw oysters at each of two restaurants in Miami. A stool specimen yielded toxigenic Vibrio cholerae O1 biotype El Tor, serotype Inaba. The results of toxin gene probing of the organism recovered from the patient differed significantly from those of other V. cholerae O1 isolates from the Gulf Coast and elsewhere in the world. A program of active surveillance identified no other cases of cholera in Miami. The source of the raw oysters eaten by the patient was traced to Louisiana. Her case represents the first reported case of cholera associated with eating raw oysters.

Aged↗
PubMed1965

Fungistatic Performance of 10,10'-Oxybisphenoxarsine in Exterior Latex and Asphalt Coatings.

10, 10'-Oxybisphenoxarsine has been found to be outstanding in its activity against bacteria and fungi. Parallel tests with known fungistats for comparison (2,3,4,6-tetrachlorophenol and phenylmercuric acetate) have demonstrated its superior activity and persistence in an exterior acrylate paint film and in an asphalt coating. In view of its superior antimicrobial activity and its persistence, it can be used in applications in which there is no danger of its ingestion. Further field trials are in progress to evaluate 10, 10'oxybisphenoxarsine in paint, asphalt, wood, and in marine pilings.

Journal Article↗
PubMed1965

Antimicrobial activity of several bis-methanethiolsulfonates.

We determined the inhibitory end point of a series of bis-methanethiolsulfonates, CH(3)SO(2)S(CH(2))(n)SSO(2)CH(3) (n = 2 to 6), and correlated the structures with antimicrobial activity. Eleven microorganisms were used in the evaluation, and the maximal activity occurred when the methylene chain length was five or six. The effect of CH(3)SO(2)S(CH(2))(5)SSO(2)CH(3) (PMTS) on respiration of Aerobacter aerogenes and Staphylococcus aureus was studied at various stages of their growth cycles. The effect on viability was correlated with that of respiration in the case of A. aerogenes. Respiratory inhibition caused by PMTS varied with the growth phase of both organisms, being most pronounced when the cells tested were taken during the period of transition from the log to stationary phase. The lethal effect on A. aerogenes was also greatest at this time. During the period of increased sensitivity, the antimicrobial activity of PMTS appears to be closely related to cell respiration. The delayed rate of kill otherwise observed may reflect an impairment of protein metabolism through reaction with sensitive SH groups.

Bacteria↗