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Biomedical subjects

W H Yuan

Publications and source records attributed to W H Yuan.

At least 19 recordsLinked to original sources

Image evaluation of suprazygomatic masticator space lesions.

In order to understand lesions involving the suprazygomatic masticator space (SZMS) demonstrated on computered tomography (CT) or magnetic resonance (MR) images, we collected 45 cases of lesions in SZMS. There were hematomas in 26 cases, tumors in 16 cases, and abscesses in 3 cases. The location of these lesions in compartments of the SZMS and adjacent structures was analyzed. Most commonly hematoma was found in the deep loose connective tissue (80.8%), followed by the superficial dense connective tissue (61.5%). Only 2 SZMS hematoma involved the superficial fat pad. Five patients had air accumulation in the SZMS, and all were in the deep fat pad and with maxillary sinus fracture. Of the sixteen cases which were tumors, 12 were extended from adjacent structures, and four were primary tumor. In cases of tumor, compartments of SZMS involved most frequently were temporal muscles (15 of 16 cases), followed by deep fat pad (8 of 16 cases). The connective tissue layer of SZMS is a communication pathway for superficial spread of infection, hematoma, or tumor invasion to or from the scalp and face. Compartments of deep fat pad and temporal muscle are also pathways for the spread of disease to or from the face, intracranium and orbit. The primary tumors in infratemporal fossa and SZMS are rare. Malignant tumors in SZMS usually come from surrounding spaces.

Adolescent↗

[A primary study on the relationship between condyle position and anterior distraction for cross bite caused by cleft lip and palate].

OBJECTIVE: To evaluate the changes of the position of the mandibular condyle in cleft lip and palate patients with secondary bony cross-bite deformity after early orthodontic treatment with extraoral bow and facial mask. METHODS: The TMJ topograph 6 months before and after treatment was investigated in 8 patients. The width of the anterior,superior and posterior space of the TMJ was compared prior to and post treatment. RESULTS: The results showed that there was no significant difference in the width of the three spaces of the TMJ before and after treatment. CONCLUSION: The position of the mandibular condyle had no significant change after maxillary anterior distraction with extraoral bow and facial mask.

English Abstract↗

[Primary study on speech training of palatalized misarticulation].

OBJECTIVE: In this paper, differences in 10 palatalized misarticulation patients between pre-and post-speech training were reported to discuss the training methods of palatalized misarticulation. METHODS: 10 palatalized misarticulation patients (6 male, 4 female) with the age of 4-14 years were included in the study. All the patients had undergone systematic speech therapy,and their speech intelligibilities were analyzed. RESULTS: All patients' speech intelligibilities after training were significantly higher than those before training. /s/, /z/, /c/, /d/, /t/, /zh/, /ch/, /sh/, /j/, /q/ and /x/ were often involved. CONCLUSION: Palatalized misarticulation was caused by abnormal palato-lingual contact which leads to decreasement of speech intelligibility. Speech training is the only method to correct the wrong articulation position and articulation method. The key of training methods for palatalized misarticulation is to plane the dorsum and release the tongue's retroflex.

English Abstract↗

[Assessment of velopharyngeal function in normal speech by CT].

OBJECTIVE: To find an objective method to assess velopharyngeal function by CT. METHODS: Three dimensional conformation of the velopharyngeal orifice of 30 subjects with normal speech at rest and /i:/ position were observed and analyzed. The linear distance and area of velopharyngeal orifice were measured and analyzed statistically. RESULTS: The average minimal area of velopharyngeal orifice at/i:/ position was 11.92+/-11.73 mm(2). The physical RVPI was 4.03+/-4.03%. Coronary closure was the most common type of velopharyngeal contraction which accounted for 50%, semi-ring type being 30%, and ring type being 20%. No sagittal closure were seen in this study. There were 70% subjects whose position of velopharyngeal closure was at the level of the first cervical vertebra, 26.7% above the level and 3.3% below it. The arrange of velopharyngeal closure was 9-12 mm in 83.4% subjects, and 3-6mm in 16.6%. CONCLUSION: As a method of assessing velopharyngeal function, CT can not only observe the conformation of velopharyngeal orifice in three dimensions, but also quantitatively analyze the velopharyngeal function.

English Abstract↗

[Early face mask treatment for maxillary hyperplasia in patients with cleft lip and Palate]

OBJECTIVE: Early interfering orthodontics were used to treat maxillary hyperplasia by face mask and extra-oral bow technique in teenages.The position changes of maxilla after orthodontic treatment were evaluated.METHODS:The cephlometric variables before and after treatment were measured.Variables after treatment were compared with normal values in children with same ages,and changes of the maxillary position was determind.RESULTS:The position of the maxilla after orthopedics was significantly advanced (P<0.001),but there was still difference from normal values.CONCLUSION:In the peroid of mixed dentition of patients with cleft lip and palate,early orthodontics on maxillary hyperplasia could stimulate maxillary development and growth,remove or improve crossbite,extra-oral bow and face mask were efficient tools for this kind of patients.

Journal Article↗

[The normal people's parameters of the velopharyngeal incompetence(VPI) by cephalometric analysis]

OBJECTIVE:To estimate velopharyngeal incompetence(VPI)in patients with cleft lip and palate,we seek for the normal people's parameters of VPI. METHODS:Studying on 222 normal people with VPI by cephalometric analysis,the parameters of the normal people have been set up.RESULTS: There was remarkable correlationship between the rate of velopharyngeal sagital restriction by cephalometric analysis and the rate of VPI by nasopharyngeal endoscope.CONCLUSION:Cephalometric analysis is useful to estimate the function of velopharyngeal closure and mobility of the soft palate.

Journal Article↗

[Presurgical infant orthopedics in complete bilateral cleft lip and palate reconstruction]

OBJECTIVE:This study want to effects on using intraoral-appliance treatment of complete bilateral left lip and Palate in clinic.METHODS:Using Lisson's method preliminary evaluated to effect of presurgical infant orthopedics complete bilateral cleft lip and palate.A sample of 4 cases of 18 weeks infant complete bilateral cleft lip and palate.2 of they are males, others are females.All of they had received presurgical infant orthopedics,Using intraoral appliance. comparison of before and after cast analysis.Evaluate anteiro posteior I, tranverse,oblique degree of the lateral segment, pretrusion premaxilla position change.RESULTS:Every patients after orthopedics treatment had retracted premaxilla come back,corrected of oblique of premaxilla,had lateral segments growth equally on both side,their inclination should be similar.CONCLUSION:Intraoral-appliance can successfully improved malarrangement maxilla of bilateral cleft lip and palate.

Journal Article↗

[Observation in vivo histological response induced by imlplanted domestic poly-DL-lactic acid plates]

OBJECTIVE:To analyze the histological response and biocompatibility to implanted domestic PDLLA plates in vivo METHODS:Bilateral artificial fractures were created in mandibular bodies in dog and internal fixed with domestic PDLLA plate,TM plate respectively;meanwhile,a domestic PDLLA plate was imlplanted in femur.The interfacial soft tissue around the plates were collected and performed histological study RESULTS:All the skin wound healed well without abscess and fistula formation. From 2 to 4 weeks after the operation,the inflmmatory granulomatous response around the intenal fixation PDLLA plates was more serious than that of the control,in which more macrophages,plasmocytes and less lymphocytes,mononuclear cells infiltrated CONCLUSION:Domestic PDLLA plate is an inert internal fixation material with good biocompatibility, which induced a non-speciflc foreign reaction

Journal Article↗

[Observation of the biodegradation of domestic poly-DL-lactic acid plates in vivo]

OBJECTIVE:To analyze the degradation and related factors of domestic poly-DL-lactic acid(PDLLA) plates in vivo. METHODS: The artifical transverse fractures in mandibular bodies of dogs were created and internal fixed with domestic PDLLA plates as experimental group,the implanted PDLLA plates in femurs as control.A certain time after the operation,the plates in fractured and implanted regions were collected and undertaken macroscopy and scanning electromicroscopy(SEM),meanwhile the fracture-healing status was evaluated. RESULTS: With time going on,the surface of domestic PDLLA plates y and density of micro-holes among poly-DL-lactic acid molecules in the PDLLA plates increased gradually.16-20 weeks Domestic PDLLA plates can be gradually biodegradation in vivo,in which it is correspondent with and accelerative the fracture-healing process.

Journal Article↗

Experimental study of radiation effect on the mandibular microvasculature of the guinea pig.

OBJECTIVE: This experimental study was performed to explore the intraosseous microvascular alterations in the irradiated mandible and to increase understanding of the pathogenesis of osteoradionecrosis. METHODS: One hundred twenty-eight guinea pigs were grouped according to different radiation sources and dosages. Fractioned radiation was delivered to the right mandibles. Dental extractions were conducted at 1, 3, and 5 months respectively, after radiation. One month later, the animals were examined by means of gross observation, histopathology, and microvascular corrosion castings. RESULTS: Histologic evaluation showed bone absorption within 2 months following radiation. Four months later, the number of osteocytes decreased and pyknosis and empty lacunae were commonly seen. The casting specimens revealed under scanning electron microscopy that capillary disconnection and obliteration with subsequent vein shrinkage aggravated over time. In the nonhealing dental extraction site, a large-scale vascular network defect presented with focal capillary proliferation around. CONCLUSIONS: The capillary is the part most vulnerable to the damage caused by radiation in the vascular system of the mandible. On the basis of "hypovascular, hypoxic, hypocellular" structure, local microcirculation failure induced by the trauma-repairing process leads to occurrence of osteoradionecrosis of jaws.

Animals↗

[A comparison of the effects of 180kv X-ray radiation and cobalt-60 radiation on the jaws of the guinea pigs]

OBJECTIVE: Study of the effects of 180kv x-ray and cobalt-60 radiation on jaws and enhance the understanding of pathology of osteroradionecrosis of jaws(ORNJ).METHODS: 128 guinea pigs were grouped according to different irradiation sources and doses.Fractioned radiation from both sources was delivered in right mandible.The teeth extractions were conducted one week prior to radiation and 1,3,5 months after radiation respectively.Following radiation,the guinea pigs were examined by gross observation, x-ray film and histopathological examination at regular interval. RESULTS: Bone resorption occured within 1 month after irradiation as result of osteoblast inhibition and osteoclast activation.From 2 to 4 month afterwards,the number of osteocytes reduced and pyknosis, empty lacunae as well as obliteration of small vessels in periodontal membrane were commonly seen.The teeth extractions conducted at 3 months,5 months after radiation lead to ORNJ in 7 amimals (14.6%).CONCLUSION: 180kv x-ray radiation was far more damaging to jaws than cobalt-60 radiation.The dental extraction is an important factor inducint the development of ORNJ.

Journal Article↗

[Evaluation of speech aid's function with air flow pressure techniques]

OBJECTIVE:To evaluated of speech aid's function with air flow pressure techniques. METHODS: The study group contained 12 patients with cleft palate,submucous cleft palate and congenital velopharyngeal insufficiency who had been found to have VPI(velopharyngeal insufficiciency) and hypernasal speech and were scheduled for speech aid. RESULTS: It was confirmed that study was to assess the relationship between oral-nasal resonance with and without the speech aid. CONCLUSION: The speech aid be able to improve the velopharyngeal function in some VPI patients,also it is useful clinical results for the speech therapiist.

Journal Article↗

[Cephalometric analysis of maxillary development in adult unoperated cleft palate patients]

OBJECTIVE: Analysis of maxillary development in adult unoperated cleft palate patients.METHODS:Lateral cephalometric radiographs of 37 case of adult unoperated cleft palate (UCP) patients were analyzed with computerized aided image system, 20 normal adults were as a control group.RESULTS: Showed that maxillary anteroposterior distance of UCP group is shorter than normal control group (P<0.05) and there is no significant difference on superoinferior distance of jaw between the UCY group and normal control group (P>0.05).CONCLUSION:The cleft palate intrinsic deformities can interfere maxillarv normal development.

Journal Article↗

[A study on speech training methods for patients following cleft palate repair]

OBJECTIVE:This study is to improve speech articulations of patients following cleft palate repair. METHODS: 20 cases were treated with systemic speech trainning. The methods included testing speech articulations of pre-and post-training blowing and systemic speech training whose program was consonant (first step), syllable (second), word (third), sentence (forth), and (fifth). RESULTS: It is showed that their articulations improved from 48.1% to 97.1% on average,and,the improvement in speech was highly significant statistically(P<0.0001).The younger the patient was,the shorter the training circle was. CONCLUSION: Speech training can correct habit of compensatory pathologic articulation and improve articluation of patient following cleft palate repair.

Journal Article↗

[Cephalometric analysis in the patients of TMJ ankylosis with OSAS: Skeletal morphology]

By cephalometric analysis of 18 normal men and 12 men who got TMJ ankylosis with obstructive sleep apnea syndrome(OSAS),the authors reported that there were cephalometric characteristics in the patients:the craniomaxillofacial bones displacement posteriorly and superiorly,and demonstrated that it is key to advance the patients' jaws and enlarge the upper airway space.

Journal Article↗

[Cephalometric analysis in the patients of TMJ ankylosis with OSAS: Soft tissue morphology]

By cephalometric analysis of 18 normal men and 12 men who got TMJ ankylosis with obstructive sleep apnea syndrome(OSAS),the authors reported that there were cephalometric characteristics in the patients:the posterior airway space(PAS) decreased(P<0.001),and the rate of (TA+SPA)/OPA remarkably increased(P<0.001),so the two parameters are significant for the diagnosis and treatment of the patients.

Journal Article↗