Biomedical subjects

W Haferland

Publications and source records attributed to W Haferland.

At least 19 recordsLinked to original sources

PubMed1989

Human malic enzyme-2 polymorphism in the GDR.

Leukocyte malic enzyme-2 (ME2) phenotypes were studied in 313 blood samples from unselected subjects and in 241 human brain tissue samples (postmortem examinations) from the northern part of the GDR. The ME2(2) frequency was 0.34 and the same in blood and brain samples. The gene frequencies were in agreement with those previously reported for European populations. A study of 71 mother-child pairs supported a genetic transmission by two alleles at an autosomal locus.

Brain↗

PubMed1985

Presentation and statistical examination of three-factor association in the HLA system.

Three-factor associations in the HLA system are frequently tested statistically by well-known procedures using 2 X 2 X 2 contingency table analysis. The coupling index DABC given in many publications is suitable for none of these procedures. A more meaningful statistical test for the index DABC is described.

Biometry↗

PubMed1981

[EsD gene defect in the myocardium of a 33-year-old man (author's transl)].

While establishing normal EsD patterns in human body tissues, one exception was found among 253 samples (23 different tissues from each of 11 cadavers). No EsD activity could be established in the zymogram for the myocardium extract from a 33-year-old man although the other tissues, erythrocyte hemolysate, and spermatocystic secretion were characteristic for the type 2-1.

Adult↗

PubMed1981

[Simultaneous representation of EsD, DIA, GLO, and UDPGP in a starch block (author's transl)].

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Carboxylesterase↗

PubMed1981

[Histoelectrophoresis for typifying enzyme systems from human body tissue (author's transl)].

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Electrophoresis, Starch Gel↗

PubMed1980

[Glyoxalase I (GLO) in human tissues (author's transl)].

In 49 autopsies (23 samples of tissue per case--skin, skeletal muscle, cerebrum, cerebellum, tongue, tonsil, submandibular gland, thyroid gland, lymph node, lung, heart, stomach, small and large intestine, liver, spleen, suprarenal gland, kidney, prostate, testicle, uterus, uterusleiomyoma and bone marrow) identical GLO phenotypes with analogous blood pattern were found.

Adult↗

PubMed1977

On the population genetics of the red cell glyoxalase I (GLO).

The GLO phenotype distribution was studied in the population from the Rostock area (n = 233). The gene frequencies of GLO alleles were estimated to be GLO1 = 0.4249, GLO2 = 0.5751. The electrophoretic separation was achieved on horizontal starch gel.

Erythrocytes↗

PubMed1975