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Biomedical subjects

W Hallermann

Publications and source records attributed to W Hallermann.

At least 19 recordsLinked to original sources

Automatic extraction of the mid-facial plane for cranio-maxillofacial surgery planning.

Recently developed computer applications provide tools for planning cranio-maxillofacial interventions based on 3-dimensional (3D) virtual models of the patient's skull obtained from computed-tomography (CT) scans. Precise knowledge of the location of the mid-facial plane is important for the assessment of deformities and for planning reconstructive procedures. In this work, a new method is presented to automatically compute the mid-facial plane on the basis of a surface model of the facial skeleton obtained from CT. The method matches homologous surface areas selected by the user on the left and right facial side using an iterative closest point optimization. The symmetry plane which best approximates this matching transformation is then computed. This new automatic method was evaluated in an experimental study. The study included experienced and inexperienced clinicians defining the symmetry plane by a selection of landmarks. This manual definition was systematically compared with the definition resulting from the new automatic method: Quality of the symmetry planes was evaluated by their ability to match homologous areas of the face. Results show that the new automatic method is reliable and leads to significantly higher accuracy than the manual method when performed by inexperienced clinicians. In addition, the method performs equally well in difficult trauma situations, where key landmarks are unreliable or absent.

Algorithms↗

[Clinical jargon--memorabilia].

As in all professions, there has always been a clinical jargon. The bustle and anonymity of a large hospital complex are bound to affect the mentality of those who work there and the way they see themselves; the result, reflected in the jargon, is not always advantageous.

Humans↗

Significance of pleural and sputum concentrations for antibiotic therapy of bronchopulmonary infections.

Tests were done with various antibiotics (ampicillin, carbenicillin, cefazolin, cefotaxime, cephradine, ticarcillin) in order to determine the significance of sputum and pleural concentrations for adequate therapy of bronchopulmonary infections. In a total of 19 chronic bronchitis patients, it was found that the attainable sputum concentrations were rather low and that individual fluctuations were great. No clear connection was evident between dosage and concentration of antibiotics in the sputum. In 17 patients with exudative pleurisy, test data yielded in pleural kinetics largely corresponded with data from animal experiment models. The pleural cavity can be described as a partial extracellular, extravascular compartment in which the concentration course probably correlates more to the interstitial lung concentrations than to that of the sputum.

Anti-Bacterial Agents↗

[On the treatment of Terrien's marginal dystrophy (author's transl)].

Many techniques have been described for the treatment of Terrien's marginal dystrophy, which are intended to reduce the astigmatism, reduce complications and prevent a progression of the disease. Described here is a technique for performing a lamellar keratoplasty without rupturing the very thin recipient cornea while preparing the graft bed.

Corneal Dystrophies, Hereditary↗

[Genetic aspects of keratoconus (author's transl)].

The diverging views expressed in the literature on the inheritance of keratoconus gave us cause to examine the genetic relationships in 304 cases of keratoconus from our own clinic material. In the 22 cases (19 families) where two or more family members were affected, the genetic relationships generally indicated a multifactorial mode of inheritance, although isolated dominant or recessive variants could not be excluded. The assumption of a multifactorial inheritance is further supported by the occurrence of keratoconus in connection with various syndromes, as well as the fact that keratoconus does not only express itself in sharply defined stages, but also occurs in all possible degrees, from almost normal to the extreme.

Chromosome Aberrations↗

[Results of lamellar keratoplasty for recurring pterygium (author's transl)].

Although difficult, recurrent forms of pterygium are seldom seen in central Europe, they cause considerable therapeutic problems because they cannot be cured by simple dissection and conjunctivoplasty. A useful method of treatment in these cases is the marginal, lamellar keratoplasty, which, according to the type of involvement, can take the shape of a sector, ring, horseshoe, or semicircle. If the pterygium is extensive and affects the center of the cornea, a subtotal, lamellar keratoplasty can be performed. The rate of recurrence in the group of 35 lamellar keratoplasties which we performed amounted to a satisfactory 31%. Only rarely did a pronounced astigmatism cause a decrease in the visual acuity postoperatively. Essential for the success of the procedures are exact surgical techniques and local use of atropine and cortison postoperatively. Just as with other surgical procedures, however, the lamellar keratoplasty cannot be considered the perfect method for all pterygiums.

Astigmatism↗

[Accidents and lethality in ocular surgery (author's transl)].

The mortality and morbidity rates in eye surgery are low as compared to other surgical specialities. The lethality rate is not, however, as low as one might suppose if one follows the fate of patients which require postoperative transfer into other (non ophthalmologic) clinics. The morbidity rate differs markedly, depending on whether a local or general anesthetic is used. Following local anesthetics, the incidence of pulmonary emboli was 2.4 times greater, and thrombophlebitis twice as common as with general anesthetics, whereas cardiac complications occurred more frequently with general anesthetics. Pre- and postoperative measures are presented which have proven useful in the reduction and prevention of such mishaps.

Adult↗

[On secondary endoepithelial dystrophy of the cornea due to non-magnetic anterior chamber foreign body (author's transl)].

Secondary endoepithelial dystrophy of the cornea can be uncharacteristic and lead to misdiagnoses. A foreign body in the anterior chamber producing an endothelial dystrophy is often recognized late, or not at all. Clearing the cornea with glycerin facilitates the gonioscopic examination. Foreign bodies found in the anterior chamber following war wounds of traffic accidents were most commonly glass, quartz or stone. After removal of the foreign body, the endothelial dystrophy can heal spontaneously. A perforating keratoplasty of large diameter is indicated if the dystrophy persists or increases. The results are reported.

Adult↗

[On the semiology and genetics of keratoglobus (author's transl)].

A report on the pedigree in familial occurrence of keratoglobus in 3 offsprings probably having autosomal, recessive inheritance of this feature. A deviation from the normal axial length of the ball, the anterior chamber depth and the length of the vitreous space could be found by ultrasonography in 4 eyes with keratoglobus.

Adult↗