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Biomedical subjects

W He

Publications and source records attributed to W He.

At least 91 records · Page 5Linked to original sources

[A clinical investigation on cataract surgery with 2.8 mm incision].

OBJECTIVE: The results of phacoemulsification which was performed through a 2.8 mm clear cornea tunnel incision and foldable intraocular lens (IOL) implantation were analyzed. METHODS: On 126 eyes with cataract of 105 cases, phacoemulsification with foldable IOL implantation was randomly performed. The results of postoperative vision, refraction, corneal edema, anterior chamber flare and the rate of corneal endothelial cell loss were retrospectively summarized. RESULTS: The uncorrected visual acuities of postoperative 1 day, 3 days, 1 week, 2 - 3 months, >or= 0.5 were in 102 eyes (81.0%), 108 eyes (85.7%), 112 eyes (88.9%) and 112 eyes (88.9%), respectively. The mean diopters of astigmatism at postoperative 3 days, 1 week, 1 month and 3 months were (1.09 +/- 0.51) D, (1.02 +/- 0.47) D, (0.88 +/- 0.52) D and (0.81 +/- 0.62) D, respectively. The mean diopters of astigmatism at postoperative 1 week, 1 month and 3 months compared with that before the surgery had no significant difference (P > 0.05). The comparison between the preoperative astigmatism and that at postoperative 3 months showed that only about 0.08D of change existed. The postoperative corneal edema and anterior chamber flare were mild, the anterior chamber configuration remained well, and the rate of endothelial cell loss was 11.9%. CONCLUSIONS: The surgical incision is small and easy to perform. Postoperatively, the reaction is mild, the change of astigmatism is small in degree, the best visual acuity can be obtained at the early stage and the refractive status is stable, thus the duration for restoration is greatly shortened.

Adolescent↗

[Ultrastructure study on extraocular muscle of infiltrative exophthalmos].

OBJECTIVE: To investigate histopathologic and ultrastructural changes of extraocular muscles (EOMs) in infiltrative exophthalmos in order to collect some evidences of pathogenesis. METHODS: Ten EOM samples in infiltrative exophthalmos were obtained after operation. Each of them was cut into two pieces. One of them was stained with HE and observed by light microscope. Another one was sectioned with ultrathin method and observed by transmission electron microscope. RESULTS: Under the light microscope, the extraocular muscular cells had no significant abnormality at the early stage, while at the middle and late stage, sarcoplasm coagulation, granular degeneration, vacuolization and necrosis were found in the cells. Under the electron microscope, there were disturbance and disappearance of the Z line in part of muscular fibers in early cases; at the middle and late stage, various degrees of sarcoplasmic reticulum dilatation, myofilament lysis and destruction with formation of vacuoles, secondary lysosome and remnant bodies were seen. In severe cases, the muscular cells could be completely destroyed and phagocytosed by macrophages, fibrosis occurred and myofibroblasts were found in some cases. CONCLUSIONS: The EOMs in infiltrative exophthalmos are destroyed in various degrees, and the muscular cells may be the target cells in Graves' ophthalmopathy.

Adult↗

[The clinical significance of the dynamic change in serum cardiac troponin T in burned patients].

OBJECTIVE: To evaluate the diagnostic value of serum cardiac troponin T (cTnT) in myocardial injury in burned patients. METHODS: Sixty-two burned patients were cardiac divided into 3 groups, i.e. mild and moderate (M, n = 25), severe (S, n = 22) and extra (E, n = 15) groups on the basis of patients' severity. Radio immunoassay was adopted to detect serum cTnT and CK-MB in patients of all groups on 1, 3, 7 and 14 postburn day. Ultrasound cardiogram and ECG (electrocardiogram) were employed to monitor cardiac function. Twenty healthy volunteers were enrolled in the control group (C). RESULTS: (1). The serum cTnT levels at all time points in patients in S and E groups were evidently higher than those in C group (P < 0.01) and paralleled very well with the severity of the patients' injuries. (2). CK-MB exhibited similar change as that of cTnT. (3). There exhibited abnormal findings with ultrasound cardiogram and ECG in five cases in E group. CONCLUSION: The dynamic changes in serum cTnT and CK -- MB could well reflect the degree of the myocardial injury in burned patients, and cTnT was much more reliable as an index of myocardial injury than the serum enzymes due to its higher specificity and sensitivity.

Burns↗

[Protocol and quality control for Chinese food and nutrition surveillance system in 1998 (1998 CFNSS)].

Establishment of Chinese Food and Nutrition Surveillance System is of great importance in providing information on food consumption behavior and nutrition status of the people which is essential for health, economic planning and agriculture development. Sampling of CFNSS is based on the 145 sites Disease Surveillance Point (DSP) System built by Ministry of Health, and in conjunction with the 600 sites Household Social Economic Survey System founded by State Statistics Bureau. According to indicator system developed by the Ministry of Health for stratification, strata of urban, general rural and less-developed rural were defined and 40 sites were randomly sampled as national sample. The CFNSS sample was the common sub-sample of DSP system and the SSB Household Survey System that makes sharing of information resources possible. The 40 sites are distributed in 26 Provinces/Municipalities/Autonomous Regions. All the sites information was collected on body weight and height of children under 6 years of age, and questionnaire covering the basic family information, feeding practice and disease, health conditions of the households were surveyed by interviews. Whole year food consumption data collected at the sampled households by SSB Urban Household Survey Team and Rural Household Survey Team in the previous year was provided. Comprehensive data analysis was done to formulate the information on the relationship of food, nutrition and health. The protocol, methodologies and principles for the survey are described. 5 sites of CFNSS were selected for quality evaluation on the anthropometric measurement and questionnaire interview. The body weight and length of 20 children of 3-5 years of age in each of 5 sites was measured again. The result showed that the completeness of questionnaires interview was 96%, the rate of logic error was zero. There was no significant difference between the results measured by supervisor and investigator and no significant error on repeated measurements. The reliability of data R = 0.95. The results showed that the data was accurate and reliable.

Adolescent↗

[Protocol for sampling of Chinese food and nutrition surveillance system (CFNSS)].

Based on the 145-site Disease Surveillance Point System (DSP) of the Ministry of Health in conjunction with 600-site Urban/Rural Household Socio-economic Survey System of State Statistic Bureau carried out by the Urban Household Socio-Economic Survey Team and Rural Household Socio-Economic Survey Team. Three strata including urban, general rural and less-developed rural were defined. Sample size of 16,000 children was designed according to the estimate of 5% underweight prevalence of children under 6 years of age. 40 sites were sampled by stratified random sampling, involving 14 urban sites, 17 general rural sites and 9 poor rural sites in 26 provinces. The total population of the 40 sites is 20.678 million, which is 1.7% of whole population of the country. 400 children under 6 years of age were sampled by Multi-stage Cluster Sampling at each site. The consistency of age distribution of children between the sample and the National Population Census data in 1990 by Goodness of Fit Test indicated the representativeness of the sample is reliable.

Adult↗

[Current situation and trend of child growth in China].

Data of Food and Nutrition Surveillance in 1990, 1995 and 1998 was analyzed; it indicated the evident improvement of weight and height of children under 5 in the past eight years. The prevalence of underweight were reduced from 8.0% in 1990 to 2.7% in 1998 in the urban, and in the rural, the prevalence were 22.0% and 12.6% respectively. The reduction of prevalence of stunting in the urban decreased from 9.4% to 4.1%, and in the rural from 41.4% to 22.0% in the same period. During 1990-1995, weight of children under 5 went up evidently, but linear growth improvement was very slow and did not match the weigh gain. Height of children increased in a higher speed during 1995-1998. Height and weigh of age groups indicated that 6-18 month was the critical period for prevention of malnutrition of children under 5. The paper further analyzed the favorable changes of the attributable factors of malnutrition, such as diarrhea, safe drinking water, breastfeeding, education level of mothers, household diet and income during this period. The conclusion is the remarkable nutrition improvement of children under 5 in 1990s is the consequence of the rapid socio-economic development of China.

Adult↗

[Exclusive breastfeeding and growth of infants under 4 months in China].

Data collected at the 40 CFNSS sites in 1998 was analyzed on the relationship of exclusive breastfeeding and the growth, diseases of infant aged under 4 months. The results showed that the exclusive breastfeeding rates (EBF) of children under 4 months were 53.7% in urban and 76.6% in general rural, but was 64.6% in the poor rural. EBF rate of the stunted children was 57.3% that was significantly lower than the infants with normal length. 73.0%. The infants EBF under 4 months were 0.36 kg heavier, 1.2 cm longer, and WAZ 0.4 and HAZ 1.53 higher than the non-EBF infants. Prevalence of diarrhea were 13.1% among EBF and 29% in non-EBF infants. Logistic regression analysis showed that odds ratio (OR) of stunting for non-EBF infants was 2.19, OR of diarrhea was 2.74.

Breast Feeding↗

[Relationship between growth of young children and complementary feeding].

Description analysis, correlation regression analysis and logistic regression analysis were applied to evaluate the impact of complementary food on the growth of children from the aged 4 to 24 months, results on the effect of the complementary feeding were presented. Among children under 2 years in poor rural areas, 42% of them got complementary food containing animal food, 30.5% got milk, 57.8% got starchy foods, and 48.6% got vegetables and fruits. The coverage of complementary food containing animal food, vegetables/fruits was only half of that in the urban areas. Analysis revealed significantly positive correlation of HAZ, WAZ of all age group of children under 2 years with the appearance of animal foods, vegetable and fruit in the complementary food, but there was no significantly correlation with starchy foods. According to the regression coefficient, it was estimated that the prevalence of stunting aged 18-24 months could be reduced 2.6 percentage points if 10% increase of coverage of animal food containing complementary food in the CFNSS site was achieved. Logistic regression analysis showed the odds ratio (OR) of non-animal food complementary food for stunting was 2.21 for children aged 4-6 months, 1.73 for 6-12 months, 2.81 for 12-18 months, 2.58 for 18-24 months, OR for underweight was 2.87 for 12-18 months, and 2.08 for 18-24 months.

Child Development↗

[Status and economic losses of respiratory infection and diarrhea of children under 6 years].

Based on the data collected from the CFNSS in 1998, the status and trends of respiratory infection and diarrhea of children and the economic losses caused by the two diseases were analyzed. The prevalence of two-week respiratory infection of urban children under 6 was 23.75% and 21.97% in the general rural, and 26.03% in poor rural. The peak of respiratory infection of rural children was at 6-18 months, but in the urban, that was at age of 3-4 years. Before 2 year of age, the respiratory infection was higher in the rural, and after that age it was higher in the urban. Since 1990, the prevalence of respiratory infection went up and increased 9.5 percentage points over 8 years in the urban, the percentage point of increase was 6.9 in the rural during the same period. In 1998, the prevalence of diarrhea of rural children under 6 was 7.0%, higher than in the urban, which was 4.3%. The prevalence reduced from 9.4% to 4.3% during 1990-1998 in the urban, and in the rural from 13.0% to 7.0%. Weight and height of children with diarrhea incidence were significantly lower than children without diarrhea. Calculation based on the cost for the episodes of the two diseases and the disease prevalence was made and estimate of the economic losses was 11,793 yuan (RMB) for urban, 5458 yuan (RMB) for rural areas.

Child↗

[Food consumption and dietary pattern in China during 1990-1998].

Based on data of food consumption collected in the household survey of State Statistics Bureau in 1990 and 1995, consumption of soybeans and its production decreased in all household. Urban population over-consumed animal food, intake of cereals reduced and energy share of cereals was dropped to less than 60%. Rural population consumed mainly cereals, animal food, fruit and oil consumption was lower. 1998 data showed that the animal food consumption increased along with income increase, but vegetable oil consumption kept stable. Dietary pattern of urban household were still relatively rational, but animal food consumption still needed to be increase in the rural households, and more attention should be paid to the poor households. Enhancement of nutrition education and promotion of soybean consumption and production for nutrition improvement for both urban and rural population was recommended to make urban diet to meet the goals of a balanced diet and the rural diet to be nutritionally adequate.

China↗

[Assessment of dietary pattern in China with desirable dietary pattern].

Applying desirable dietary pattern (DDP) to analyze the quality of the diet in urban and rural household in 1995 and 1998 was presented. The results showed that: urban people should adjust the structure of their diet, to level down the increasing trend of animal food, as a replacement, more soybean consumption should be encouraged. Rural people should increase moderate amount of animal food and oils, and increase of vegetable/fruits and overall non-staple foods could keep the diet quantitatively and qualitatively improved and balanced. Promotion of soybean consumption in the rural households was the most feasible and effective way of improving nutritional quality of the diet in the rural in the near future.

China↗

[Sampling survey for iodine content of iodized salt in household of CFNSS in 1998].

The sampling survey for iodine content of iodized salt was conducted in 36 food and nutrition surveillance sites of CFNSS in 1998 in China, which covered 26 provinces, 362 portions of salt samples. The average compliance rate was 76.0%, 83.2% in Urban area and 71.9% in Rural. Iodine content of salt less then 20 mg/kg at the rural households was 20.4%, and 9.9% in urban.

Female↗

[Reporting system of Chinese food and nutrition surveillance in 1998].

The software of reporting system for Chinese food and nutrition surveillance in 1998 is the key part of China Food and Nutrition Surveillance System (CFNSS) in 1998. By means of modern information technology to process the contents of questionnaires of CFNSS, and using professional software to conduct data analysis, useful information has been created. The software consists of 4 modules: data entry program for CFNSS, anthropometric calculation, data analysis and data transmission. It is also an open system, the users can use the tool offered by the system to conduct further analysis based on their own situation, and even developing a surveillance system.

China↗

[Supercritical extraction of Alpinia officinarum and GC-MS analysis of its components].

In order to find the effective components and new pharmaceutical effect of Alpinia officinarum, and further exploit it, we extracted its essential oils with the technique of Supercritical-CO2 fluid, then confirmed there were 27 components in Pot I And 111 components in Pot II by using the chemical component analysis and the computer information retrieval in the GC-MS system.

Alpinia↗

[GC-MS analysis of essential oil components of Alpinia oxphylla].

Essential oil Components of Alpinia oxphylla were analyzed by way of applying gas chromatography, mass spetrography and computer interpretation; essential oil was abtained by supercritical CO2 fluid, thus we got 193 peaks in oil from Pot I and 210 peaks in oil from Pot II as well as identify 139 and 155 compounds respectively.

Alpinia↗

[Experimental studies on antioxidation of extracts from several plants used as both medicines and foods in vitro].

OBJECTIVE: The scavenging effects of 8 extracts from several plants used as both medicines and foods on oxygen free radicals were studied in vitro. METHODS: Chemiluminescence (CL) method and ultra-weak luminescence technique were used, meanwhile, macrophage respiratiory burst was also carried out to evaluate the antioxidation reaction. RESULTS: The scavenging activity on superoxide anions (O2-.) differed in the following order: extract of clove (CE) > black tea (BTE) > green tea(GTE) > grape peel/seed (GE) > or = oologn tea (OTE) > > tumeric (TE). In Fenton reaction for hydroxyl radicals (.OH), the order as follows: BTE > CE > or = GTE > GE > OTE > > TE. Most extracts have stronger eliminating efficiency on .OH than on O2-. except CE, which may scavenge the O2-. formation more efficiently. After macrophages (5 x 10(6) cells/ml) were stimulated with phorbol myristate acetate, BTE showed stronger inhibiting action than CE on respiratory burst in macrophages. The results of ultra-weak luminescence measurement indicated that the extracts could delay and depress the DNA damage in CuSO4-Phen-Vc-H2O2-DNA chemiluminescence system. CONCLUSIONS: It suggests that the tested antioxidants could decrase the formation of O2-. or .OH, some have chain-breaking function and preventative function during DNA damage.

Animals↗

[Transposition of expanded cervical-shoulder skin flaps for the repair of cicatricial contracture deformity of neck].

OBJECTIVE: To evaluate the efficacy of expanded cervical-shoulder skin flap in the treatment of cicatricial contracture deformity of neck, and improve the method for the repair of soft tissue defect of neck. METHOD: 12 patients with cicatricial contracture of neck were treated by pre-expanded cervical-shoulder skin flap and then transposition for the reconstruction of the defect after cervical scar resection. RESULT: All the 24 flaps were survived. Postoperative follow-up for 6 months to one year showed that the cervico-mandibular function and the external appearance of the flaps were satisfactory without swelling and contracture. CONCLUSION: Pre-expanded cervical-shoulder skin flap is available for the treatment of cicatricial contracture deformity of neck.

Adolescent↗

[The preparations and spectroscopic studies of infrared radiating materials].

ZrO2 and ZrO2-Al2O3 samples have been prepared by precipitation method, and characterized by FTIR, NIR FT-Raman, XRD and IR emission spectra, respectively. The result showed that these samples are the better infrared radiating materials, which have high efficiency and excellent properties. When compared with pure ointment, ZrO2-Al2O3 prepared has more strong infrared emission peaks. The application of infrared radiating materials in ointment may have a good effect on thermal infrared absorption vibration and absorption of medicine by sick part of body.

Aluminum Oxide↗