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Biomedical subjects

W Hort

Publications and source records attributed to W Hort.

At least 91 records · Page 5Linked to original sources

[Histometrical studies of liver parenchym in two cirrhotic livers (author's transl)].

Livers of two patients suffering from cirrhosis were weighed at post mortem, and found to have weights of 510 resp. 640 g. The quantity of hepatocytes was measured histometrically and estimated to be approx. 210 g in both patients; this means, that total liver mass in these patients was reduced to approximately 30% of normal, and that hepatic insufficiency had been incumbent in both of these patients. Difficulties in the methods of measuring the quantity of normal liver parenchyma in cirrhotic livers are discussed. Initiation of hepatic coma in liver cirrhosis is dependent in the first place, but not exclusively, upon the degree of reduction of liver parenchyma.

Aged↗

[Epidermoid cyst of the tibia (author's transl)].

Case report on a large epidermoid cyst in the proximal tibia in a 42-year old woman. Scrutiny of the available literature shows that this is the first recorded case of an epidermoid cyst in a long bone.

Adult↗

[Morphology of myocardial perfusion (author's transl)].

Disturbances of myocardial perfusion are mostly due to obstructive coronary atherosclerosis. The shape of the narrowed lumen is polymorphic. The localization of severe stenoses is not influenced by risk factors. Atherosclerotic changes are more frequent in the coronary arteries than in their large branches. There is a good agreement between the localization and the size of the infarct and the poststenotic or postocclusive perfusion area. As a rule there are only few atherosclerotic lesions within samll intramural arteries and arterioles of the myocardium. We could not find a positive correlation between the extent of sclerotic changes in large coronary arteries and arterioles.

Angiocardiography↗

The importance of smooth muscle cells in the development of foam cells in the gastric mucosa. An electron microscopic study.

Foam cells in lipid islands of the stomach can develop from both histiocytes and smooth muscle cells. With increasing storage of lipid vacuoles in smooth muscle cells, loosening of the myofilament arrangement and decrease of the dense areas subjacent to the plasma membrane occurs. Endoplasmic reticulum and the cisternae of the Golgi-apparatus dilate, the cell organelles increase initially and the basement membrane of the smooth muscle cells is fragmentarily formed. Only in incompletely formed foam cells can the origin from smooth muscle cells be recognised, in their final state their histiogenesis is seldom apparent.

Aged↗

Quantitative study on the size of coronary artery supplying areas postmortem.

The relative amount of myocardium perfused by the three large coronary arteries was determined in 171 human hearts postmortem. Roentgenograms of transverse serial sections of the ventricular myocardium enabled planimetrical measurements. With little variation, an average of 41.5 per cent of the entire ventricular myocardium was supplied by the left descending coronary artery. Both left branches supplied an average of 63.8 per cent and the right coronary artery supplied 36.2 per cent of the myocardium. The size of supplying areas, in particular that of the right coronary artery and the left circumflex branch, was mainly dependent upon the coronary artery types. As a rule cardiac hypertrophy did not influence the size of coronary supplying areas as much as did the coronary artery types. Only very few hearts revealed that the myocardium was supplied to a greater extent by the right coronary artery than by the left (5.3 per cent). There is a close relationship between the size of the myocardial supplying area and the lumen of the corresponding coronary artery.

Adolescent↗

[Bilateral retro- and subauricular fistulae with eversion of the epithelial lining (author's transl)].

An infant with multiple congenital anomalies was observed: bilateral cleft lip and palate, left cystic kidney, bilateral retroauricular fistulae with ectropion of the epithelial lining. These fistulae ended in tissue of thymus. They are derived from the ductus thymopharyngicus. In this case a large ectropion was constated on both sides, which was in this form not described before. The early case history, the therapy and the rare histological findings are described and the up to date unknown abnormality with figures represented.

Abnormalities, Multiple↗

[Site and shape of the most severe stenoses in coronary arteries and their relationship to the risk factors. Postmortem findings (author's transl)].

Out of a great number of hearts investigated post-mortem by coronary arteriography and quantitative histology, 437 coronary arteries of 202 hearts had severe stenoses with a lumen reduction to less than 50 per cent. Mainly these most severe obstructions lay between 2 and 5 cm behind the aortic ostium. In the right coronary artery the frequency curve showed a smaller peak, a smaller decrease, and an inconsiderable second peak in the periphery. Perhaps the slow calibre reduction of the right coronary artery is significant for these findings. The narrowed lumen mostly lay a little eccentric and had an oval shape. A slit-like shape was a rare finding. Only in 20 per cent of the severe stenoses a normal intima was preserved in parts of the circumference of the coronary artery. Among 113 patients the following risk factors were known: hypertony, diabetes mellitus, cigarette smoking and hypercholesterinemia. Significant differences in the localisation of the most severe stenoses were not recognizable under the influence of these risk factors.

Aged↗

[Human coronary arterial patterns (author's transl)].

Limits of the supply area of the three large coronary arteries (right, left descending and left circumscribed branches) were determined by post-mortem angiography of 400 human hearts. The largest variation was demonstrated in the region of the posterior ventricular wall and the apex. Most frequently the border of the supply region between right and left circumflex branches extended across the middle of the left posterior wall. Hearts in which the left ventricular posterior wall was supplied from both right and left circumflex branches (normal type) constituted 82% of all cases. In the right-coronary dominant type (10%) the left ventricular posterior wall, at least at the base, was supplied by the right coronary artery, while in the left-dominant type (8%) the right coronary artery did not supply any part of the left posterior wall. At the apex the left descending branch rose dorsally by about 0.2-5.0 cm in 70% of cases, while the posterior interventricular branch only rarely supplied the apex (1.1%). The left coronary artery showed most variations in the anterior wall. It divided into two in 41%, into three with an additional diagonal branch in 53% and into four in 6%.

Adolescent↗

[Static and dynamic studies on finger arthrodeses].

Some general techniques in arthrodesis of finger joints are described. Then biomechanical measurements were made after compression arthrodesis with screws, crossed KIRSCHNER wires, tension band wiring, compression plates (Swiss AO), and self compression plates, creascent shaped (MITTELMEIER). By screws, a maximal compression between 25 and 34 kp is achieved. Using a selfcompressing, bent, crescent shaped plate, one gets a compression of about 18 kp. This osteosynthesis resists a high deflection momentum if edgewise inserted.

Arthrodesis↗

[Biomechanical investigations of osteosynthesis at metaphys area of tibia and femur with selftensed angle plates (author's transl)].

Straight pressure plates create an eccentric tension force as well as an osteosynthesis with angle pressure plates. Both kinds of plate incline to gape the osteosynthesis and/or fracture gap. Therefore an overbending or additional angle allowance is necessary. In our biomechanical investigations we showed that at average bone stability, an overbending of the angle respectively an additional angle allowance of 3 degrees is most favourable. Uniform distribution of power transmission can be achieved at the entire osteotomie level using large and small angle plates with appropriate plate thickness and plate tension force. Sufficient stability in mobilisation is guaranteed without additional cast fixation.

Biomechanical Phenomena↗

[Biomechanical tests on osteosynthesis with small-bone plates (author's transl)].

Plating in handsurgery has become a more frequently used method since the special instruments of the Swiss AO and the self-compression plates of Mittelmeier (made by Osteo AG) have been introduced. The results of biomechanical measurements, comparing the interfragmental compression power and tensile strength of the small-fragment-plates of the AO with the crescent-formed plates of Mittelmeier are reported. The compression power of the first reach their maximum by 8 kp, the latter an average of 20 kp. A gapping of the fracture occures under a deflection-momentum of 4 kp - cm using AO-plates and 10 kp - cm using the crescent-formed plates. The bending stiffness under deflection momentum to the off side of the plate is in the crescent plate 10 times higher. Only an angulating bending in the middle gives in both plates an all over good contact to the fragments. Finger osteosyntheses are very rigid against a deflection momentum in the level of the plate. (Regarding that, we fixe the plate sidewise on the bone.) Our conclusion is, that the better biomechanical stability of the self-compression plates--Mittelmeier-plates--is a result of the higher compression powers.

Biomechanical Phenomena↗