Interchangeable oxygen and air connectors.
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Air↗
Biomedical subjects
W Hurst
Publications and source records attributed to W Hurst.
Temporal order judgments with amnesia.
The hypothesis that patients with anterograde amnesia fail to recognize the temporal relations among recognizable past events was evaluated. Experiment 1 showed that order recognition for words in a list was at chance levels even though event recognition was significantly above chance. The same pattern did not obtain for intact adults. Experiment 2 examined event and order recognition for news events. Amnesics' event recognition for news events was quite accurate and comparable to controls, yet their order recognition was significantly below that of controls, again at chance levels. It is argued that the failure to encode the temporal relations among events has broad consequences for memory performance in general.
Adult↗
Lymphocyte reactivity of workers exposed to carcinogenic and non-carcinogenic chemicals.
Immunological studies have shown an increased lymphocyte reactivity in patients with early stage bladder cancer and individuals with pre-stage T1 exposed to bladder carcinogens (2-naphthylamine and industrial 1-naphthylamine containing 4-8% 2-naphthylamine) before 1952-that is, those at high risk of developing bladder cancer. Because of the close chemical similarity of Tobias acid (2-naphthylamine-1 sulphonic acid) to 2-naphthylamine, the lymphocytotoxicity of workers exposed to this chemical was investigated. The results show that the workers using Tobias acid unlike those exposed to 2-naphthylamine have lymphocytes with a normal range of reactivity towards bladder cancer cells, which is in keeping with the suggestion that Tobias acid is non-carcinogenic. The probable reason for its non-carcinogenicity is that the relatively very large size and hydropholic properties of the sulphonic acid group prevents enzymic action on the amino group by steric hindrance. The present lymphocytotoxicity results strengthens our earlier conclusion that the observed increased lymphocyte reactivity in workers exposed to bladder carcinogens is specific.
2-Naphthylamine↗
Prognostic importance of specific immunoreactivity in occupational bladder cancer.
Sixty-eight workers with a history of exposure to a bladder carcinogen were followed up to see whether changes in lymphocyte immunoreactivity to a bladder-cancer-cell target were predictive of the development of neoplasia of the urothelium. A twofold or greater increase in reactivity was strongly associated with the development of abnormal urinary cytology suggestive or indicative of malignant change. Changes in immunoreactivity to a non-bladder-cancer-cell target did not have this association. The findings support the possibility that changes in lymphocyte immunoreactivity may be used to predict the onset of bladder cancer in people exposed to bladder carcinogens.
2-Naphthylamine↗