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Biomedical subjects

W I Anderson

Publications and source records attributed to W I Anderson.

At least 55 records · Page 3Linked to original sources
PubMed1988

Klossiella equi induced tubular nephrosis and interstitial nephritis in a pony.

Heavy renal infection in a pony with Klosiella equi resulted in moderate diffuse tubular nephrosis and tubular rupture. Multifocal non-suppurative interstitial nephritis was associated with ruptured tubules. Ultrastructural examination of sporoblasts demonstrated both the presence of a bilaminated membrane encasing organisms and nuclear budding. Endogenous corticosteroid production probably led to the development of an immune-compromized state and subsequent extensive parasitic replication.

Adrenal Cortex↗
PubMed1988

Subclinical lumbar polyradiculopathy in multiple aged mammalian species.

Lumbar polyradiculopathy, characterized by ballooning myelin sheaths was diagnosed in multiple aged mammalian species including two horses, a cow, a squirrel, a woodchuck, a rabbit, a guinea pig, a hamster, and a mouse. The lesion was subclinical, and considered an incidental, age-related finding.

Aging↗
PubMed1988

Neoplastic angioendotheliomatosis in a dog: an angiotropic lymphoma.

Neoplastic angioendotheliomatosis was diagnosed in a nine-year-old, intact male German Shorthaired Pointer exhibiting progressive neurological signs over a six-month period. At necropsy, there was multifocal asymmetric, hemorrhagic necrosis within the cerebral hemispheres, centrum semiovale, caudate nucleus, and internal capsule. Histologically, there was extensive intravascular proliferation of pleomorphic mononuclear cells within the brain and multiple parenchymatous organs. Transmission electron microscopy demonstrated the absence of intercellular junctions between neoplastic cells. These cells were not attached to the vascular lining endothelium; Weibel-Palade bodies and a basement membrane were lacking. By indirect immunofluorescence, positive cytoplasmic staining of intravascular neoplastic cells for IgG was demonstrated. Peroxidase-antiperoxidase technique for Factor VIII related antigen was negative. As in man, this rare neoplastic disorder appears to be a lymphoma, apparently of the B cell line.

Animals↗
PubMed1988

Renal dysplasia in a pig.

A diagnosis of renal dysplasia was made in a six-month-old, male, mixed-breed pig. Both kidneys were small, firm, slightly pitted, and contained an indistinct corticomedullary junction. Histologically, primitive tubules were present surrounded by an abundant loose, mesenchymatous stroma. Occasionally, tubules were markedly dilated and lined by a pseudostratified columnar epithelium forming epithelial mats that obscured the lumina. Immature glomeruli were present. Multifocal glomerular sclerosis was evident. Other mature glomeruli were enlarged and characterized by mesangial cell hyperplasia forming an arborizing pattern.

Animals↗
PubMed1988

Calcinosis circumscripta of the tongue in a cat.

A nodular mass present on the ventral surface of the tongue in a mature, castrated male domestic short-haired cat was diagnosed as calcinosis circumscripta. The cat died of end-stage renal disease. Histologically, the multilobulated mass was composed of acellular, fractured loculi separated by thin bands of a connective tissue stroma. Loculi contained a light red crystalline substance, surrounded by amorphous basophilic mineralized material. No specific relationship is suggested between the end-stage renal disease and the tongue lesion.

Animals↗
PubMed1988

Acute pelvic limb paralysis induced by a lumbar fibrocartilaginous embolism in a sow.

A diagnosis of fibrocartilaginous embolism was made in a mature mixed-breed sow with a history of an acute onset of pelvic limb paralysis. Within a single section of lumbar spinal cord, there was severe focally-extensive infarction of the right ventral gray horn. Within affected white matter, there was dilatation of multiple myelin sheaths with concurrent axonal swelling. A smaller focus of infarction was present on the contralateral side. Arteries at the periphery of both lesions contained a blue-gray material with staining characteristics similar to that evidenced by the nucleus pulposus present within intervertebral discs. Grossly, no abnormalities were present within the vertebral column.

Acute Disease↗
PubMed1988

Incomplete subaortic stenotic rings in domestic animals--a newly described congenital anomaly.

A newly described congenital heart anomaly, the incomplete subaortic stenotic ring was detected at necropsy in four dogs, one cat, one cow, one horse, one sheep and one pig. These structures were grossly and histologically similar to complete subaortic stenotic rings, being composed of variably dense interlacing bands and sheets of fibrous connective tissue. In all nine cases, their presence at necropsy was considered an incidental finding.

Animals↗
PubMed1987

Segmental atresia of the transverse colon in a foal with concurrent equine herpes virus-1 infection.

Segmental atresia of the transverse colon was observed at necropsy in a neonatal foal. The dorsal and ventral components of the large colon were fused, and ended blindly. The small colon was collapsed and completely closed at its cranial end. The right and left dorsal and ventral colons were fused into one blind-ended tube. Histologically, eosinophilic intranuclear inclusion bodies demonstrative of Equine Rhinopneumonitis were present in the thymus.

Animals↗
PubMed1987

Mast cell tumor in the mandibular salivary gland in a dog.

A mast cell tumor in the mandibular salivary gland was diagnosed in a 9-year-old English Setter. Dense infiltrating sheets of mast cells were present within the mandibular salivary gland, the medial retropharyngeal lymph node and in two subcutaneous masses on the flank. The salivary gland, lymph node, and masses were excised. The dog was treated postoperatively with the histamine receptor antagonist, cimetidine and the alkylating agent, chlorambucil. The tumor recurred at the angle of the mandible 4 months later and the dog was killed.

Animals↗
PubMed1987

Calcinosis circumscripta in a domestic short-haired cat.

A poorly circumscribed, subcutaneous mass present on the dorsum of a young mature, male domestic short-haired cat was diagnosed as calcinosis circumscripta. Histologically, the mass was composed of multiple, fragmented loculi with a crystalline, light red center surrounded by dense, amorphous, mineralized material. Loculi were separated by variably-dense bands of a connective tissue stroma. The cat was otherwise healthy, and the mass was excised without recurrence.

Animals↗
PubMed1987

Eurytrema procyonis in a New York fox.

A fox infected with canine distemper virus had multiple Eurytrema procyonis trematodes within the major pancreatic duct. The ductal epithelium was slightly hyperplastic and there was mild periductal fibrosis present. There was dilatation of the pancreatic duct containing the parasites. Numerous eosinophilic intracytoplasmic inclusions were present in the epithelium of multiple organs, including the pancreatic ducts.

Animals↗
PubMed1987

Thiamine deficiency encephalopathy with concurrent myocardial degeneration and polyradiculoneuropathy in a cat.

Hyaline degeneration, myofiber fragmentation, and mineralization were present in the left ventricle of an aged, female Siamese cat with both clinical and histopathological evidence suggestive of a thiamine deficiency encephalopathy. Both a thiamine related biochemical lesion and neurogenic myocardial degeneration ("Brain-Heart" Syndrome) may have contributed to the development of the heart lesions. A concurrent lumbar polyradiculoneuropathy, characterized by ballooning myelin sheaths with axonal degeneration, was considered an incidental, age-related finding.

Animals↗