Prophylactic appendicectomy during caesarean section in a developing community.
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Adult↗
Biomedical subjects
W I Onuigbo
Publications and source records attributed to W I Onuigbo.
Adolescent breast masses in Nigerian Igbos.
In the Igbos of Nigeria, most adolescent breast masses were due to gynecomastia in males and to fibroadenoma in females. The peak ages for both diseases differed from those reported in a recent American series. An exotic finding was a mammary mass due to onchocerca worms. Curiously, there were as many as two cases of a rare tumor, namely, alveolar soft part sarcoma.
Adenocarcinoma↗
Selectivity and rejectivity in cancer metastasis.
In cancer metastasis, "selectivity" denotes the formation of secondary tumor in an organ in such a manner that its localization pattern is peculiar. The opposite phenomenon should be recognized and called "rejectivity". In man, carcinomas appear to spread selectively to the umbilicus, whereas lymphomas seem to reject that site. In all probability, recognition of the twin theory of selectivity and rejectivity will stimulate research on cancer dissemination.
Humans↗
Jaw tumours in Nigerian Igbos.
Sixty-three cases of jaw tumours in Nigerian Igbos are reviewed. Burkitt's tumour, fibro-osseous lesions, ameloblastoma and carcinoma were seen in progressively older patients. The Igbos, like fellow Nigerians, suffer from ameloblastoma at relatively earlier ages than other Africans. Although the Igbos are as prone to keloid formation as other Negro peoples, it is noteworthy that this fibrous tendency was not evident in their jaw tumours. None of the tumours exhibited melanin pigment. The incidence of Burkitt's tumour appears to be lower in the easterly Igbos than in the ethnic groups living in the westerly part of Nigeria.
Adolescent↗
Infarction of accessory spleen.
A rare disease that can mimic acute appendicitis is infarction of accessory spleen. It may occur in children and is difficult to diagnose preoperatively. Greater awareness of this entity may show not only that it is associated with other intraabdominal anomalies but also that it is more common in the tropics than elsewhere. Two cases are reported.
Acute Disease↗
Lip lesions in Nigerian Igbos.
Lesions of the lip seen over a 7-year period at a central laboratory serving the Igbos of Nigeria are reviewed. In approximately 8,500 surgical specimens, there were 63 jaw tumors but only 16 lip lesions. Two of lip lesions alone were carcinomas. Both were (a) squamous celled, (b) associated with sunlight-induced degeneration of the dermal collagen, and (c) found in young adult albinos. Accordingly, albinism should be recognized as one of the etiologic factors in lip cancer. The appropriate preventive action is the wearing of wide-brim hats by albinos.
Adolescent↗
Clinical awareness of vulvo-vagina metastaeses in choriocarcinoma: case reports.
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Adult↗
Chromomycosis caused by Philaphora pedrosoi in eastern Nigeria.
Three cases of chromomycosis from Eastern Nigeria are described. The aetiological agent was identified as Phialophora pedrosoi. Amphotericin B cleared most of the lesions in one case while 5-fluorocytosine gave a complete cure in another case.
Adult↗
Genital tuberculosis and reproductive function.
Interesting hypotheses about the effects of genital tuberculosis on reproductive function are that diseased men may in rare instances transmit the condition to their female partners and that diseased women are usually sterile unless they conceived and gave birth before the onset of their lesions. These two hypotheses were reviewed with the help of biopsy materials obtained from the Igbos of Nigeria and were considered, as a whole, to be valid in this West African ethnic group.
Adolescent↗
Comparative study of bowel lymphosarcoma in childhood.
Five cases of lymphosarcoma of the bowel in Nigerian Igbo children are presented. They were found to be similar to an Australian series in the following respects: boys were more commonly affected than girls; affected children were all aged over two years; and the two main modes of presentation were intussusception and a localized abdominal mass. Unlike Australian children, Nigerian Igbos did not present with features suggestive of acute appendicitis.
Australia↗
Relevance of race in management of testicular tumours.
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Biopsy↗
Acalculous cholecystitis in Nigerian Igbos.
Twenty-six patients undergoing cholecystectomy for suspected gallbladder disease in hospitals serving the Igbos of Nigeria were studied. Sixteen patients had chronic acalculous cholecystitis, seven exhibited cholelithiasis, and three showed normal gallbladders. Of the sixteen with acalculous cholecystitis, there were ten males and six females whose ages averaged twenty-eight and forty-two years, respectively. This disease deserves worldwide comparative studies.
Adult↗
Tuberculous peritonitis in Nigerian Igbos.
An account is given of 30 Nigerian patients of the Igbo ethnic group whose biopsies showed tuberculous peritonitis. The maximum incidence occurred in the 20-39 year age group and the female: male ratio was 2:1. The commonest clinical findings were abdominal pain and swelling and ascites. An increase in the mean age was found in Igbos suffering from tuberculous peritonitis compared with those who had tuberculous peripheral lymphadenitis.
Adolescent↗
Encephaloceles in Nigerian Igbos.
A survey of surgical specimens submitted to a central laboratory suggests that the Igbos of Nigeria are a further ethnic group in whom the anterior encephalocele is comparatively common.
Encephalocele↗
A biopsy study of gallstones in Nigerian igbos.
Within 6 years, approximately 7,500 surgical specimens were collected at a central laboratory serving the Igbos of Nigeria. Only 28 specimens were gallbladders. Gallstones were found in 5 females and 2 males. As in other developing communities in which the diet consists largely of traditional foods, pigment stones outnumbered cholesterol stones, the ratio being 6:1. The know complications were single instances of carcinoma and rupture of the gallbladder.
Adult↗
Cancer of the oral cavity in Nigerian Igbos.
An unselected biopsy material of 31 Nigerian Igbo patients with cancer of the oral cavity is presented. The descending order of localization was gingiva, palate, tongue and floor of mouth. Burkitt's tumour was limited to the jaw and affected older rather than younger children. There was scarcely any preponderance of squamous cell carcinoma in males. It would appear that cancer of the oral cavity is not a great problem in the Igbos and that potent carcinogens concerned with the causation are lacking in the community.
Adolescent↗
Pattern of angiomas in the Igbos of Nigeria.
Almost all angiomas fall into three main groups--hemangioma, lymphangioma, and glomangioma. Fifty-one such angiomas were found in approximately 7500 surgical specimens examined at a central laboratory serving the Igbos of Nigeria. The youngest patient was aged 19 days and the oldest 70 years. Most patients presented in the first two decades of life and both sexes were equally affected. Hemangiomas greatly outnumbered the other angiomas; most were cavernous and tended to thrombose, fibrose, or calcify. Lymphangiomas frequently exhibited lymphoid tissue, some showing germinal centers. Glomangiomas occurred mostly in the upper extremity as small, painful masses.
Adolescent↗
Granular cell myoblastoma in Nigerian Igbos.
Three cases of granular cell myoblastoma occurring in the Igbos of Nigeria are reported. In this ethnic group the tumor has shown several typical features as follows: it is rarely diagnosed preoperatively; it is found more frequently in the oral cavity and breast than in most other sites; and it is in the maxilla of girls that it usually presents congenitally. A unique presentation in this ethnic group occurred in the perineum. The lesion found in this site appears to be the first to be reported in the literature.
Adult↗