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Biomedical subjects

W I Worret

Publications and source records attributed to W I Worret.

18 recordsLinked to original sources
PubMed1992

Prevalence of dysplastic nevi in healthy young men.

Young white men (1176 men, mean age 20 years, age range from 18 to 26 years) were examined for dysplastic nevi. In 78 patients (6.63%), 107 clinically dysplastic nevi were observed, demonstrating all three NIH criteria (diameter greater than 5mm, irregularities of border, irregularities of color) suggestive for clinically dysplastic nevi. Of these, 71 nevi in 52 patients were excised and examined histologically, 46 nevi in 26 patients were not excised due to lack of patients' consent. Fifty-two of 78 (66.6%) patients with clinically dysplastic nevi agreed to excision. In these, seven nevi (13.5% of patients or 9.86% of all nevi excised) were confirmed by histology. According to these data, three additional patients with dysplastic nevi would have been expected among the 26 patients who refused surgery. Referring to the entire study group, the prevalence of dysplastic nevi in young white men is expected to be 0.85%.

Adolescent↗
PubMed1992

[Osteoma cutis. Pathogenesis and therapeutic possibilities].

No efficacious therapy for the treatment of increasing and spreading cutaneous ossification is yet established. We report a 52 year old white female with multiple miliary osteomas of the skin involving face, chest and back. The patient has a history of acne vulgaris. A therapeutic trial with a diphosphonate (etidronate disodium) was started in order to stop marked progression and appearance of new lesions. In accordance with the two previously described cases of the literature we failed to achieve any improvement. Clinical features, etiology, classification and therapy of osteoma cutis are discussed.

Breast Neoplasms↗
PubMed1992

[Stewart-Bluefarb syndrome].

We describe a 17-year-old Turkish girl with painful ulcerative pseudo-Kaposi lesions on the left foot and partial giant growth of the same leg. Stewart-Bluefarb syndrome is discussed with reference to this case.

Adolescent↗
PubMed1990

[Halo eczema and nevus cell nevi (Meyerson nevi)].

In the same way as a halo of depigmentation surrounds a sutton naevus, a halo of eczema can appear around a naevocellular naevus. This phenomenon was first described in 1971 by Meyerson, but publications on the topic are relatively sparse. We report a patient who consulted us because of such lesions. A review of literature is appended.

Adult↗
PubMed1989

[Exacerbation of rosacea in HIV infection].

A 38-year-old male homosexual patient, who had suffered from hepatopathy for many years and from rosacea since 15 years, showed pronounced exacerbation of the rosacea following HIV infection.

AIDS Serodiagnosis↗
PubMed1989

[Association of idiopathic acropustuloses to HLA antigens and their relation to psoriasis].

Immunogenetical findings can contribute to the understanding of diseases of unknown etiology. It has, however, become difficult to define the borderlines between related diseases, since a vast amount of individual facts have been reported. For this reason, immunogenetical findings should only be seen as a part of general pathology. Our study, which makes use of HLA markers, is an attempt to provide a better definition of idiopathic acropustulosis, and to differentiate it more clearly from psoriasis.

Acrodermatitis↗
PubMed1988

Abnormal cutaneous nerves in incontinentia pigmenti.

Cutaneous nerves showed multiple ultrastructural abnormalities in a patient with incontinentia pigmenti. Fetal nerve bundles were seen both in the dermis and entering the epidermis. A cell with some Schwann cell features was identified above the basal layer amid keratinocytes. Dermal melanophages were in close apposition to Schwann cells. All of these features suggest that neural structures may be abnormal in incontinentia pigmenti and play a role in transfer of melanin from epidermis to dermis.

Biopsy↗
PubMed1988

[Modern methods of acne therapy].

Today the treatment of acne vulgaris offers a broad spectrum of topic and systemic therapeutics. With these a optimal therapy in different acne-phases is practicable, and the possibility of scar formation is inhibited. The particular groups of substances are discussed regarding indication, action and contraindication.

Acne Vulgaris↗
PubMed1988

[Autosomal dominant genetic dermatoses and their association with internal cancers].

In this short review we attempt to high-light a number of syndromes in which the observant physician can occasionally diagnose a cancer-associated syndrome prior to development of internal malignancy and aid the patient and his physician in appropriate management, be it closer monitoring or therapeutic interventions.

Chromosome Aberrations↗
PubMed1981

[Semimalignant" osteoma cutis].

A tumor is reported which originated rom an osteoma cutis and expanded into the surrounding tissue by infiltration and destruction. Histologically, there were no signs of malignancy. In cell culture there grew populations of bone-like tissue with highly active metabolism and negative contact inhibition. Therapeutic trials with diphosphonate are discussed.

Calcinosis↗
PubMed1978

[Congenital, plaque-like osteoma of the skin in an infant].

A plaque-like cutaneous osteoma in a male infant is described and compared with 12 remarkably similar cases from the literature. An important differential diagnosis is that of pseudohypoparathyroidism and it has to be excluded by the examination of the calcium and phosphorus metabolism. There are two possible explanations for the etiologie of osteoma cutis, an osseous hamartom, or a metaplasia of mesenchym cells. Because of some important reasons we prefer the hamartom concept.

Diagnosis, Differential↗