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Biomedical subjects

W J Alexander

Publications and source records attributed to W J Alexander.

52 records · Page 3Linked to original sources
PubMed1979

Simple primary tuberculosis in an elderly woman.

The diagnosis of primary tuberculous infection was made in a 78-year-old woman. The chest roentgenographic findings were remarkably similar to those often seen in children and adolescents with primary infection. Like the majority of adults with this entity, the patient was asymptomatic; the diagnosis was suspected epidemiologically and was confirmed by culture of M. tuberculosis from the sputum. As the incidence of new tuberculosis cases declines, the diagnosis of primary tuberculosis in the adult may be made more frequently.

Age Factors↗
PubMed1979

Bacteremia and meningitis following fiberoptic bronchoscopy.

Bacteremia and meningitis due to Streptococcus pneumoniae developed in a 52-year-old man 28 hours after an otherwise uncomplicated fiberoptic bronchoscopy. The patient responded to antimicrobial therapy and supportive care and later underwent pneumonectomy for carcinoma. This report reinforces previous observations that bacteremia may occasionally be associated with the performance of fiberoptic bronchoscopy.

Bronchoscopy↗
PubMed1978

Mycobacterium avium-intracellulare from a Vietnamese refugee.

Mycobacterium avium-intracellulare grew from the sputum of a Vietnamese woman, a recent immigrant, seen at a tuberculosis clinic in Birmingham, Alabama. The possibility that she had acquired this Mycobacterium in her native Vietname was considered, since current literature, indicates these agents have no predictable geographic patterns of distribution. Data indicate that outside the United States group III mycobacterial isolates are most common in Japan, Western Australia, and parts of Canada. No data are available for Vietnam. US physicians should be alert for possible nontuberculous mycobacteria in the 115,768 Vietnamese immigrants known to have entered the United States in the mid-1970s.

Aged↗
PubMed1978

Recent experience with tetanus in Alabama.

In recent years, all cases of tetanus reported in the United States have occurred either in unimmunized persons, partially immunized persons, or persons whose immunization history was uncertain. We present our experience with three unimmunized individuals who acquired this disease. One patient became ill after a "clean, minor wound." Present guidelines do not encourage immediate protection with human tetanus immune globulin (TIG) for unimmunized patients with this type of injury. We believe serious consideration should be given to modification of current recommendations to include the more liberal use of TIG, especially in nonimmune persons.

Aged↗
PubMed1975

The C syndrome.

Explore the source record for details and available documents.

Abnormalities, Multiple↗
PubMedDate not supplied

Infections in sexual contacts and associates of children with gonorrhea.

The productivity of gonorrhea case-finding among persons epidemiologically associated with children infected with Neisseria gonorrhoeae was examined. During a 33-month period, 36 cases of gonococcal infection in children prompted the examination of 244 individuals who were identified as either sexual contacts, household associates, or nonhousehold associates. Overall, we found an infection rate of 18.4% among 244 persons associated with cases of gonococcal infection in children. Of 21 sexual contacts examined, ten (47.6%) had gonorrhea. Of 223 persons associated with the childhood cases of gonorrhea, 21 (16%) of household associates and 14 (15.2%) of nonhousehold associates were found to have gonorrhea. Associates aged greater than or equal to 30 years who were not named as sexual contacts had a risk of infection significantly lower than that of younger persons examined. These results emphasize that gonorrhea screening prompted by reports of cases in children should not be limited to those persons identified as sexual contacts or household members.

Adolescent↗
PubMedDate not supplied

Risk factors for hepatitis B virus infection among women attending a clinic for sexually transmitted diseases.

Risk factors for and serologic evidence of hepatitis B virus (HBV) infection were analyzed among 557 women. Study subjects were attending a clinic for sexually transmitted diseases and enrolled in a clinical trial of nonoxynol-9 prevention of gonococcal and chlamydial infections. Seventy-eight (14%) showed serologic evidence of past HBV infection. Only age at time of serum collection was significantly associated with HBV marker prevalence (P = 0.04). None of the four measures of sexual activity taken (number of sex partners per month, frequency of sexual intercourse, number of documented episodes of sexually transmitted diseases, and lifetime number of sexual partners) were significantly related to the presence of HBV markers. For each measure, however, differences observed between HBV positive and negative subjects were consistent with what would be expected if these factors did contribute to HBV infection risk. These results support the role of heterosexual transmission of HBV infection in women and are consistent with recommendations for hepatitis B immunization of heterosexually active persons with multiple sexual partners.

Adult↗