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Biomedical subjects

W J Babler

Publications and source records attributed to W J Babler.

9 recordsLinked to original sources
PubMed1991

Role of cranial sutures in normal and abnormal skull development.

In a series of experimental studies, the effects of induced premature closure of a normal cranial suture on the normal growth pattern of the rabbit skull are reported. In general, the results indicate that the craniofacial skeleton is an integrated growing unit in which alteration in growth of one component has profound effects on growth of other components. The magnitude and type of compensatory response depend on the type of suture, i.e., cranial or facial, its location, and timing of the growth insult. It is also important to note that the timing of surgical intervention has a direct effect on the capability of the growing craniofacial skeleton to obtain a more typical growth pattern.

Animals↗
PubMed1979

Crown size-arch space relationships during human prenatal dental development.

As shown in composite reconstructions made from optically-projected measurements of 10mu frontal maxillofacial sections of 20 histologically normal fetuses and embryos in the 70-255 mm CRL range, individual differences in relative tooth size and interdental spacing are evident by 10.5-11 weeks of gestation, and age-corrected crown-size correlations (r=0.40) approximate those in postnatal life. Despite an eight-fold increase in crown dimensions, interdental spacing remains approximately constant after 150 mm CRL, suggesting that the tooth organs or the periodontal membranes are able to maintain spacing, into the third trimester.

Dental Arch↗
PubMed1976

Prenatal origin of brachymesophalangia-5.

As shown in 91 embryos and fetuses in the 41-235 mm crownrump length, brachymesophalangia-5 may be identified in prenatal time. Although the ratios involving different combinations of length of mid-5 relative to other segments yield different frequencies of BMP-5, the short middle segment of the little finger is already associated with clinodactyly and developmental eccentricity as early as the ninth week of prenatal development.

Female↗
PubMed1976

Prenatal origins of carpal fusions.

As shown in 138 embryos and fetuses in the 40-285 mm crown-rump length range, carpal and carpal-metacarpal "fusions" arise from incomplete separation of the cartilaginous precursors rather than from failure of initiation, thus accounting for the "fusions" seen in postnatal radiographs and the grooves that are evident enough in adult fusions. Radiographs selected from over 20,000 apparently normal individuals provide postnatal counterparts for the prenatal examples shown in histological sections.

Carpal Bones↗
PubMed1975

Early prenatal attainment of adult metacarpal-phalangeal rankings and proportions.

As shown in 56 human embryos and fetuses between 15 and 104 mm in crown-rump length, "adult" metacarpal-phalangeal length rankings are attained by the seventh intrauterine week and near-adult bone-to-bone ratios or proportions by the theirteenth week. Micrometric measurements of optically-projected histological hand sections show relative elongation of the distals between the 15-29 mm and 30-44 mm crown-rump range, and relative reduction to radiogrammetrically-determined adult proportions by the 90-104 mm CRL.

Anthropology, Physical↗