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Biomedical subjects

W J Clancey

Publications and source records attributed to W J Clancey.

3 recordsLinked to original sources

The learning process in the epistemology of medical information.

Progress in the past few decades in representing medical knowledge, along with the availability of low-cost, powerful workstation computers, has increased interest in encoding all medical records in electronic form. But despite the advantages of legibility, access, and automated performance reviews, computerization may also restrict what can be recorded and rigidify health care interactions with patients. Balancing the beneficial and negative effects requires an understanding of medical practice, especially the difference between human knowledge and today's computer programs. Human perceptual and conceptual capabilities bring an aspect of improvisation and reinterpretation to every human action, which in general computers today cannot replicate. Designers of medical record systems must consider the creative process by which descriptions are generated by people, as well as the collaborative process by which descriptions of past work are reinterpreted for guiding future decisions. This paper provides a framework for understanding these issues, illustrated by design opportunities.

Holistic Health↗

Antimicrobial selection by a computer. A blinded evaluation by infectious diseases experts.

An evaluation of a computer-based consultation system called MYCIN was made. Eight independent evaluators with special expertise in the management of meningitis compared MYCIN's choice of antimicrobials with the choices of nine human prescribers for ten test cases of meningitis. MYCIN received an acceptability rating of 65% by the evaluators; the corresponding ratings for acceptability of the regimen prescribed by the five faculty specialists ranged from 42.5% to 62.5%. The system never failed to cover a treatable pathogen while demonstrating efficiency in minimizing the number of antimicrobials prescribed. The study design may be useful in assessing the performance of other computer-based clinical decision-making systems.

Adult↗

Computerized consultation system for selection of antimicrobial therapy.

Mycin, a computer-based consultation system which provides to physicians antimicrobial therapy recommendations for patients with bacterial infections, is described. The consultation program arrives at therapeutic decisions using a built-in knowledge base as well as patient data entered by the physician. The system is capable of explaining its recommendations and answering questions about its reasoning process. The system's knowledge can be updated and corrected easily by infectious disease experts. At present the system is operational within a research setting; its routine use in a clinical setting will require further evaluation of its reliability and effectiveness.

Anti-Infective Agents↗