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Biomedical subjects

W J Geeraets

Publications and source records attributed to W J Geeraets.

At least 19 recordsLinked to original sources
PubMed1977

Acute corneal injury by mustard gas.

Described is an acute ocular injury caused by mustard gas. The clinical course was similar to what has been established by laboratory research. Some of the histopathologic events have been discussed in theory since no tissue sample from this reported case was available for examination.

Acute Disease↗
PubMed1976

[Electromagnetic radiation damage to the retina (author's transl)].

Basic mechanism involved in electromagnetic radiation damage to the retina are described. Those are photochemical, thermal and non-linear effects. The absorption of radiant energy by the retina occurs primarily in the visible spectral range. Different wave lengths are absorbed in different layers of the retina. Photochemical injury for minimal lesions is uniform and the damaged area may be larger than the irradiated area. Thermal injury for minimal lesions produces usually a more intense central core of damage surrounded by edema. Non-linear effects are caused by ultrashort exposure times and are produced from strong electric fields, acoustic signals, shock waves, etc. generated by high temperature gradients. Wave lengths play a part in the severity and origin of retinal damage at relative long exposure times but contribute little to retinal injury at ultrashort exposures e.g. psec ranges.

Animals↗
PubMed1976

Phototherapy of the cornea: some aspects to be considered.

To safeguard against and reduce possible harmful and undesired side effects of photon interaction with ocular structures during phototherapy of certain corneal diseases, precautionary measures should be taken. These include (1) Selection of the proper light source, strongly emitting in the effective spectral range. (2) Removal of potential harmful spectral bands which make no significant contribution to the therapeutic action. (3) Determination of the most optimal exposure energy (W/cm2). (4) Selection of the most optimal time-dose relationship. (5) Selection of the proper interval between vital staining and radiation exposure and considering possible repetition of therapeutic exposures. (6) Careful calibration of the light source to be used. (7) Adequate eye examination for visual acuity, pupillary diameter, signs of intraocular inflammation, mainly iritis with anterior chamber activity, and possible fundus pathology with special attention to maculopathy. These findings should be properly recorded before, during and after the period of phototherapy.

Corneal Diseases↗