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W J Hoogendijk

Publications and source records attributed to W J Hoogendijk.

22 records · Page 2Linked to original sources

Application of methods used in survival analysis to growth and nutritional studies.

Three statistical methods are described and illustrated with working examples. Using these methods it is possible to include all subjects involved in cross-sectional studies in calculations of results, even if the data are incomplete at the end of the investigation. The use of censored data is taken from survival analysis. It is shown that combination of the Kaplan-Meier estimate, the log-rank test and the proportional hazards model gives more satisfactory results in nutritional and growth studies.

Breast Feeding↗

Depression in Parkinson's disease. The impact of symptom overlap on prevalence.

The reported prevalence of depression concomitant with Parkinson's disease varies greatly in the literature, which may partly be explained by symptom overlap. To determine the impact of symptom overlap on the prevalence, the authors tested 100 Parkinson's disease patients for major depression (DSM-III-R) with both a standard, inclusive method and a diagnostic-etiologic, exclusive method. The authors found that the prevalence detected with the inclusive method (23%) decreased when the exclusive method was used (13%), which was mainly caused by lower scores on the item "loss of interest." The study's findings give empirical support for the relevance of the new category in DSM-IV "mood disorder due to a general medical condition."

Aged↗

Do delirium and Alzheimer's dementia share specific pathogenetic mechanisms?

Dementia is the most common risk factor for delirium in the elderly. Here we will review the evidence that proposed pathogenetic mechanisms for delirium (such as reduced cerebral metabolism, imbalance of the noradrenergic/cholinergic neurotransmission, inflammation, disturbances in neuronal systems which regulate stress and the sleep/wake cycle) are also a part of the pathophysiology of Alzheimer's disease. In particular, the role of inflammatory mechanisms in both disorders will be discussed.

Aged↗