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Biomedical subjects

W J Kopecky

Publications and source records attributed to W J Kopecky.

6 recordsLinked to original sources

Endobronchial irradiation with 192Ir in the treatment of malignant endobronchial obstruction.

From Jan 1, 1983 to April 30, 1989, 32 patients underwent 38 endobronchial treatments with 192Ir, bronchoscopically inserted for treatment of endobronchial obstructions secondary to bronchogenic carcinoma. Thirty-four of the 38 treatments were far enough apart to allow separate response analysis. Thirty of the 34 patients were symptomatically improved or stable; 22 of 24 patients who could be evaluated roentgenographically showed improved or stable chest roentgenograms, and ten of 12 patients evaluated bronchoscopically demonstrated improved patency of bronchial lumen.

Brachytherapy

Microwave leakage during patient treatment.

In light of the BRH proposed draft standard for microwave leakage of 10 mW/cm2, microwave leakage measurements were taken under two conditions. The first used a microwave tissue equivalent phantom in which leakage cata was accumulated as a function of net forward power and aperture-to-skin distance (SSD). This is similar to the BRH setup. In the second condition, during actual microwave hyperthermia treatments data was accumulated on several patients at different anatomical sites. The results of these experiments show a marked increase of microwave leakage occurring during patient treatment than that which can be predicted from static phantom results.

Humans

Using liquid dielectrics to obtain spatial thermal distributions.

A liquid dielectric has been used to determine thermal distributions for several clinically useful waveguide applicators as used in microwave hyperthermia. The system uses a saline/ethanol filled compartment placed within a temperature controlled water bath set to 37.5 degrees C. Thermal distributions are taken with a thermistor probe placed perpendicular to the electric field. In this way longitudinal and transverse cross sections of the heat deposition due to microwave interaction with the liquid dielectric can be elicited. A similar arrangement was carried out using phantom material and an infrared camera as described by Guy. Comparison of the central axis data and cross-sectional thermal distribution of these two systems shows good agreement.

Diathermy