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Biomedical subjects

W J Ott

Publications and source records attributed to W J Ott.

13 recordsLinked to original sources

Comparison of dynamic image and pulsed Doppler ultrasonography for the diagnosis of intrauterine growth retardation.

Dynamic image and pulsed Doppler ultrasonography were used to evaluate 104 potentially growth-retarded fetuses. The two techniques were compared, and then used together to predict whether or not the neonate would be growth retarded. Both ultrasonic diagnostic techniques showed good correlation with neonatal outcome, but their combined use improved diagnostic accuracy.

Blood Flow Velocity

Defining altered fetal growth by second-trimester sonography.

A method of predicting birth weight from a single ultrasound examination between 18-28 weeks' gestation was evaluated prospectively in 315 obstetric patients with singleton pregnancies. Estimated fetal weight at the time of the ultrasound examination was used to predict actual birth weight. At delivery, the percent difference between the projected and actual birth weights was then used to define whether an infant was small, appropriate, or large for gestational age. This method appeared to be accurate and showed identical relationships to the presence of abnormal fetal heart rate patterns in growth-retarded infants as did the traditional birth-weight-for-gestational-age method of defining intrauterine growth retardation.

Adult

The diagnosis of altered fetal growth.

The antenatal recognition of altered fetal growth should be an important goal for every obstetrician, because significant neonatal complications can be associated with both ends of the spectrum of altered growth. This article discusses the problems related to altered fetal growth, the difficulty in defining and diagnosing it, and some of the methods available for its antenatal diagnosis.

Birth Weight

Ultrasonically estimated weight and gestational age. Predictors of neonatal respiratory distress syndrome.

Information from 504 women who had undergone real-time ultrasound examination within 72 hours of childbirth was used to evaluate the relationship between the product of ultrasonically estimated fetal weight (in kilograms) times ultrasonically estimated gestational age (in weeks) and neonatal morbidity and mortality. If this product was greater than 40, there were no neonatal deaths (excluding severe congenital abnormalities); if the product was greater than 80, there were no cases of significant respiratory distress syndrome. These data may prove to be highly useful in the rapid evaluation of preterm labor or other obstetric complications.

Amniocentesis

Accurate ultrasonic estimation of fetal weight. Prospective analysis of new ultrasonic formulas.

Five new ultrasonic weight formulae incorporating head circumference, fetal femur length, and a correction for oligohydramnios were prospectively analyzed in a group of 198 unselected patients scanned within 72 hours of birth. Comparison with the Shepard formula showed that inclusion of these parameters slightly, but significantly, improved the random error of weight estimation. The best-fit formula was: Log(10) BW = .04355HC + .05394AC - .0008582HC X AC + 1.2594 (FL/AC) - 2.0661.

Birth Weight

The design and implementation of a computer-based ultrasound data system.

A detailed description of the development of a computer-based ultrasound data system is presented to provide the background for those physicians interested in developing or using such a system. The system was found to be highly useful for acquisition and organization of ultrasound data, and proved to be an aid both teaching and patient care.

Computers

Analysis of variables affecting perinatal mortality: St. Louis City Hospital, 1969-1975.

A marked drop in perinatal mortality at St. Louis City Hospital No. 1 (SLCH) from 1974 to 1975 (39.7 vs 20.6 per 1000 births) prompted a detailed analysis of various factors which might have effected the change. Comparisons were also made between SLCH and St. Mary's Health Center (SMHC), a private hospital affiliated with St. Louis University. The significant drop in perinatal mortality at SLCH in 1975 seems to be due to a combination of various factors: 1) improvement in antepartum care, 2) increase use of cesarean sections, and 3) the influence of intrapartum fetal monitoring.

Abruptio Placentae

The current status of intrapartum fetal monitoring.

Intensive intrapartum fetal monitoring, using direct fetal EKG leads and intrauterine pressure sensing transducers, seems to add another level of care for the fetus. As with other laboratory aids or devices, fetal monitoring data should not be exclusively relied on in decision making processes. When used with other modern monitor aids, such as scalp pH, it can aid immensely in the management of both normal and complicated labors. When fetal heart rate patterns remain normal throughout labor there can be a high degree of confidence that the fetal outcome will be good. If abnormal patterns occur, however, great care should be taken in interpreting these data, and it should be combined with the overall status of the mother and the fetus, and used together with the clinical acumen of the physician in determining a method of approach to the management of intrapartum situations. Continuous monitoring techniques can and should be applied in the neonatal nursery for intensive neonatal management and care (79,80). As experience is gained in clinical fetal monitoring and as new techniques and methods become available, intensuve intrapartum fetal monitoring will become an increasingly important and significant technique for management of labor (4, 139).

Acid-Base Imbalance

Vacuum extraction.

In the past twenty years, the vacuum extractor has gained wide use in Europe with an associated decrease in perinatal mortality. There, its use is considered by many to be much safet than a forceps delivery. Certain complications are associated with its use, but in general these are minor and transitory. On analysis, most of the serious complications reported in the literature are considered to be due to other associated factors, or to misuse of the vacuum extractor. Experience with the vacuum extractor in the United States has been minimal, and most authors feel that there are few indications for its use. Perhaps it is time that obstetricians in the United States take a more careful look at the European experience, and give the vacuum extractor a fair trial.

Birth Injuries

Perinatal mortality in the St. Louis metropolitan area.

Statistical data in fetal, neonatal, perinatal, and infant mortality were collected from various sources for the St. Louis metropolitan area (St. Louis City and St. Louis County). The overall perinatal mortality rate of 25.8 for the St. Louis metropolitan area in 1973 compares favorably with the national rate of 25.5 in 1973. The prematurity rate at St. Louis City Hospital (SLCH) is almost three times that of St. Mary's Health Center (SMHC), 12.7 in contrast to 4.8. Both the neonatal and perinatal mortality rates at SLCH are about twice the rate of SMHC, neonatal 19.5 versus 7.4 and perinatal 31.7 in contrast to 19.6. Prematurity and its complications still seem to be the leading cause of neonatal mortality. With modern obstetrical and intensive neonatal care, the survival rates for low birth weight infants has improved markedly. The combined survival rates at SLCH and SMHC, 1972 through 1974 for infants weighing 501-1,000 gms 28 percent; 1,001-1,500 gms, 74 percent; 1,501-2,5000 gms, 95.5 percent; and greater than 2,500 gms. 99.7 percent. Recent studies have shown that the long-term prognosis for these low birth weight infants, in terms of neurological or intellectual sequelae is good. Thus, a more aggressive approach to the management of perinatal problems can be expected to yield excellent results.

Birth Weight