PubMed HealthSearch

Biomedical subjects

W J Redmond

Publications and source records attributed to W J Redmond.

6 recordsLinked to original sources

Mycosis fungoides: a retrospective study.

The clinical course of ninety patients with the histopathologic diagnosis of mycosis fungoides is reviewed. An attempt is made to correlate sex, age, of onset, lesion type, and form of therapy with outcome of the disease. The data indicate that mycosis fungoides affects predominantly middle-aged males. Patients developing tumors or erythroderma in middle age or later tend to have a shorter survival. More aggressive therapy is associated with shortened survival. Most deaths were due to unknown or unrelated processes and therapeutic complications. The data support the theory that mycosis fungoides can be a relatively nonaggressive cutaneous lymphoma. In an attempt to treat aggressively, we may be exposing patients to increased mortality.

Adolescent

Experience in implementing the Mark III Rad 8 system for radiotherapy dose computations.

Rad 8 is a small, in-house computer system for calculating radiotherapy dose distributions, both for multiple field and rotational external beam techniques and for interstitial and intracavitary redium treatments. Implementing the system has its difficulties, particularly in obtaining the necessary beam profile information. Several approaches have been tried and finally a separate profile generator program was written. Other difficulties encountered with beam data storage were overcome by making minor changes to the system programs. The various calculation techniques have been evaluated, and in general found to be satisfactory, and suitable factors to be used in the inhomogeneity correction for 4 MV X rays have been calculated based on previously published measured data. An option to change beam weightings exists and this can be used to renormalize dose distributions to give percentage isodose curves relative to the prescribed tumour dose. If this procedure is followed dose homogeneity over the target volume can readily be assessed, and the exposure times may easily be calculated from the new weightings. Certain shortcomings in the rotating beam program and the radium program may easily lead to error if extreme care is not exercised.

Computers