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Biomedical subjects

W J Rosen

Publications and source records attributed to W J Rosen.

7 recordsLinked to original sources
PubMed2001

Sudoriferous cyst of the orbit.

PURPOSE: A case of sudoriferous cyst of the orbit in an adult patient is reported. This unusual cyst in the orbit has heretofore been reported only in congenital cases. METHODS: Case report. RESULTS: A 45-year-old woman sought treatment for an asymptomatic mass of the left lower eyelid. Computed tomography of the orbits showed a cystic lesion in the inferior orbit with bony remodeling. Histopathologic examination showed the lesion to be a solitary cyst lined by two to three layers of cuboidal epithelial cells with eosinophilic cytoplasm. Some of the epithelial cells contained periodic acid-Schiff-positive, diastase-resistant granules. The pathologic diagnosis was a sudoriferous cyst. CONCLUSION: Sudoriferous cysts, although uncommon, should be included in the differential diagnosis of orbital cystic tumors.

Conjunctiva↗
PubMed2000

Posterior capsule rupture after a paint-pellet injury.

We report a case in which a high-velocity paint pellet injury to the eye ruptured the posterior lens capsule. In the setting of blunt trauma, posterior capsule rupture has rarely been reported. Recognizing such a rupture allows the surgeon to plan the best surgical approach.

Adolescent↗
PubMed1999

Brainstem anesthesia presenting as dysarthria.

After having a retrobulbar injection for anesthesia before cataract surgery, a patient developed dysarthria. This was the presenting sign for penetration of the optic nerve sheath by the retrobulbar injection, with subsequent brainstem anesthesia. Thereafter, the patient demonstrated cranial nerve dysfunctions with tongue deviation, tachycardia, hypertension, and contralateral sixth and third nerve palsies. I believe this is the first documented case in which dysarthria is the presenting sign for brainstem anesthesia resulting from a retrobulbar injection.

Aged↗
PubMed1997

Delayed hyphema and intravitreal blood following intrableb autologous blood injection after trabeculectomy.

PURPOSE: To report delayed hyphema and intravitreal blood as complications following intrableb autologous blood injection after trabeculectomy. METHODS: Case report. A 44-year-old woman with hypotony and maculopathy after trabeculectomy with mitomycin C received an intrableb autologous blood injection. RESULTS: Three days after the blood injection, a hyphema formed and subsequently dispersed into the vitreous. CONCLUSIONS: Although immediate hyphema from autologous blood injection is common, hyphema may be delayed and associated with intravitreal blood.

Adult↗
PubMed1992

The effect of trabeculectomy on corneal topography.

Trabeculectomy is increasingly being performed earlier in the treatment of primary open-angle glaucoma (POAG). Surgically-induced alterations in corneal curvature resulting from filtering surgery may have a significant impact on patients, especially younger ones, whose vision may already be compromised by visual-field loss. Using data obtained by computer-assisted topographic analysis performed preoperatively and at 12 weeks postoperatively, we longitudinally studied the corneal surface changes induced by primary trabeculectomy in eight eyes undergoing surgery for POAG or normal-tension glaucoma. Additional data collected included refraction, keratometry, axial length, intraocular pressure, and pachometry. Five of eight eyes developed 1.50 to 2.50 diopters of steepening in the 90-degree meridian. One patient developed flattening in the 180-degree meridian without vertical steepening. Two patients had little change in the central optical zone. Of the six eyes with induced with-the-rule astigmatism, keratometry was less sensitive than topographic analysis in detecting the changes induced by trabeculectomy. Our data indicate that changes in corneal curvature are induced by filtering surgery, but may be undetectable without topographic analysis.

Astigmatism↗
PubMed1989

Evaluation of five procedures for measuring nonstandard doses of nifedipine liquid.

Five methods for removing the maximum volume of liquid from a nifedipine capsule were evaluated for efficiency and reproducibility, and the concentration of nifedipine in Procardia and Adalat 10- and 20-mg capsules was determined The methods evaluated were the needle puncture and squeeze method; the scissors method; the needle and syringe, one-hole method; the needle and syringe, two-hole method; and the capsule in syringe barrel method. The liquid content of 10 Adalat 10-mg capsules was removed by each method, the volume was determined by the weight and specific gravity of the nifedipine liquid, and the mean volumes of nifedipine liquid were compared. A stepwise procedure for using the needle and syringe, one-hole method was developed. The mean nifedipine concentration in Procardia 10- and 20-mg capsules was determined by ultraviolet spectrophotometry by using 30 capsules of each brand and strength. The needle and syringe methods were the most reproducible and efficient procedures for obtaining a desired milligram dosage of nifedipine from the capsules. The two-hole method would be less practical in the clinical setting, however, because it is time consuming and cumbersome. The mean assayed nifedipine concentration in the Procardia and Adalat 10- and 20-mg capsules was within 10% of the concentration reported by the manufacturer for each specific product lot number. Based on reproducibility and efficiency, the needle and syringe methods are the best methods for quantitation of liquid nifedipine doses for patient administration.

Capsules↗