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Biomedical subjects

W J Thomas

Publications and source records attributed to W J Thomas.

At least 55 records · Page 3Linked to original sources
PubMed1978

The possibility of germ cell chimaerism in dizygotic twin bulls.

A study was made of the progeny of a pair of dizygotic twin bulls whose blood group phenotypes were identical but were genotypically different, indicating a complete replacement of one of the bulls haematopoietic tissus by that of its cotwin. The study was made in an attempt to determine whether the genes of one sibling were transmitted by the other. It it were so it would follow that the germ cells of the testes were chimaeric. Blood typing of 97 progeny provided no evidence to indicate the presence of such a germ cell chimaerism.

Alleles↗
PubMed1977

Free erythrocyte porphyrin: hemoglobin ratios, serum ferritin, and transferrin saturation levels during treatment of infants with iron-deficiency anemia.

Free erythrocyte porphyrin:hemoglobin (FEP:Hb) ratios were determined on 20 infants with iron-deficiency anemia. FEB:Hb ratios were compared with simultaneously drawn serum ferritin and serum transferrin saturation levels. FEP:Hb ratios dropped steadily during treatment of the anemic infants, but remained elevated compared to age-matched nonanemic infants, until the anemia was corrected. FEP:Hb ratios detected iron deficiency when acute inflammatory disease was present. Serum ferritin levels and transferrin saturation failed to detect iron deficiency after iron therapy was started or when acute inflammatory disease was present. Measurement of FEP:Hb ratios is a reliable and practical way to make a prompt diagnosis of iron-deficiency anemia in infants.

Anemia, Hypochromic↗
PubMed1976

Cardiac arrhythmia during outpatient dental anaesthesia: the advantages of a controlled ventilation technique.

Two techniques for endotracheal anaesthesia in dental outpatients have been compared: a spontaneous ventilation technique using nitrous oxide, oxygen and halothane, and a controlled ventilation technique using nitrous oxide and oxygen, with tubocurarine and fentanyl. The latter technique has several advantages: abolition of arrhythmias induced by surgery, more rapid and hence safer recovery, avoidance of suxamethonium, and avoidance of atmospheric contamination with and possible sensitization to halothane.

Adolescent↗
PubMed1968

Transplant lung.

Explore the source record for details and available documents.

Adult↗
PubMedDate not supplied

Feeding responses to perifornical hypothalamic injection of neuropeptide Y in relation to circadian rhythms of eating behavior.

Hypothalamic injection of neuropeptide Y (NPY) can elicit eating in satiated rats, and the perifornical hypothalamus (PFH) is the site where this effect is most pronounced (48). Additionally, there is a well-documented circadian rhythm of spontaneous eating behavior. Our objective was to determine whether there are daily rhythms of sensitivity to NPY in the PFH that might contribute to this behavioral rhythm. To accomplish this, the effectiveness in eliciting eating of PFH injection of NPY was examined at six different time points in the light-dark cycle. Neuropeptide Y (78 pmol/10 nl) or vehicle (10 nl) were injected through chronically implanted guide cannulas into the PFH of satiated adult male rats and food intake was measured 1, 2, and 4 h later. In animals on 12-12 h light-dark cycles, these injections were given 1 h before and after the onset of the light and dark phases, and in the middle of these phases. Additionally, dose-response effects of NPY were examined at two points: the first hour of both the dark and the light phases. The results show that NPY was effective at every time tested, and that the magnitude of the peptide-elicited intakes was primarily additive to the underlying patterns of spontaneous intake, with only a modest daily cycle of sensitivity to NPY. Consistent with this, NPY dose-dependently increased intake in the early light and in the early dark, and the magnitude of these effects across doses was similar at these times. This suggests that the sensitivity of the PFH system mediating NPY eating exhibits only a modest daily cycle.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗