Biomedical subjects

W J van Amstel

Publications and source records attributed to W J van Amstel.

9 recordsLinked to original sources

PubMed1986

[Routine leukocyte differentiation test].

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Diagnostic Tests, Routine↗

PubMed1981

Solitary plasmocytoma of the vagina.

A 78-year-old woman with a plasmocytoma of the vagina is described. The diagnosis monoclonal IgG kappa-producing plasma cell tumour was based on immunohistochemical studies. Careful screening for other localizations including immunofluorescence of the bone marrow aspirate and in methyl-methacrylate embedded bone marrow biopsy specimen, yielded no evidence in favour of a multiple myeloma. To our knowledge only 5 patients with plasmocytoma of the vagina were previously reported, but only in the present case extensive immunohistochemical studies of tumour, bone marrow and blood were performed.

Aged↗

PubMed1978

Successful prevention of coumarin-induced hemorrhagic skin necrosis by timely administration of vitamin k1.

Successful prevention of the progression of incipient hemorrhagic skin necrosis by timely administration of vitamin K1 in a woman treated with phenprocoumon is presented. From a critical review of the literature strong evidence emerges that coumarin necrosis does only occur in cases with severe initial drug induced hypocoagulability. Non- recognition thusfar of its importance is due to insufficient knowledge of the biological activities of thromboplastin preparations presently used in the laboratory control of oral anticoagulation. All well documented cases with apparently adequate Quick values were monitored with Faktor VIII insensitive thromboplastin. Therefore, such preparations should no longer be used in anticoagulant control.

4-Hydroxycoumarins↗

PubMed1972