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Biomedical subjects

W Jez

Publications and source records attributed to W Jez.

At least 19 recordsLinked to original sources

[Radical vulvectomy using Way's method with bilateral removal of inguinal, thigh, iliac and veil lymph nodes in the clinic].

Thirty-one cards of women after radical vulvectomy in Way's mode were analysed. Metastases in inguinal, thigh, iliac and veil lymph nodes were found only in 19.35%. Authors conclude that removal of iliac and veil lymph nodes can be given up after previously negative outcome of intra-operative examination of inguinal and thigh lymph nodes. Mean period of patient's staying in hospital was long--about 40 days. In 51.6% of cases the blood group was "A", with the mean for the whole country 40.5%.

Adult

[Serum monoamine oxidase (MAO) and diamine oxidase (DAO) activity and histamine level in the blood of women during the early puerperium].

In early puerperium various biochemical changes develop in the organism. Considering the role played by MAO, DAO and histamine, and absence of a comprehensive study of this problem in this life period a study was carried out on 36 women, who were selected randomly from women giving birth through the normal pathway. Blood samples were taken in morning hours on the 1, 2 and 3 days of puerperium. In each case the activity of serum monoamine oxidase, diamine oxidase and blood histamine level were measured. The results obtained on various days of puerperium were compared. Statistical analysis was carried out using the t test for paired measurements. Increased serum MAO activity was found on the second day and was decreased then on the third day of puerperium, but it was still above the level on the first day. A successive decrease of serum DAO activity was noted in these three days of puerperium. The blood histamine level increased successively on the successive days of puerperium. Normal values of the activity of these substances in the serum were established in women delivering the fetus through the vagina. The lower normal range of MAO activity, extension of the range of DAO activity, especially of its upper range, and decreased histamine level were found. The authors discuss the causes of these results.

Amine Oxidase (Copper-Containing)

Effects of cholinomimetics, cholinolytics and atypical antidepressants in the behavioral despair test in the rat.

The effect of some cholinolytics, cholinomimetics and atypical antidepressants on behavior of rats forced to swim (in the "behavioral despair test") was investigated. In addition, the relation between the test performance and the inborn level of exploratory and locomotor activities was studied. Cholinomimetics prolonged, while cholinolytics and antidepressants shortened the immobility phase ("despair reaction"). The "despair reaction" was less pronounced in rats with high motor exploratory activity level.

Animals