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W K Richardson

Publications and source records attributed to W K Richardson.

15 recordsLinked to original sources
PubMed2000

PTS performance by flight- and control-group macaques.

A total of 25 young monkeys (Macaca mulatta) were trained with the Psychomotor Test System, a package of software tasks and computer hardware developed for spaceflight research with nonhuman primates. Two flight monkeys and two control monkeys were selected from this pool and performed a psychomotor task before and after the Bion 11 flight or a ground-control period. Monkeys from both groups showed significant disruption in performance after the 14-day flight or simulation (plus one anesthetized day of biopsies and other tests), and this disruption appeared to be magnified for the flight animal.

Adaptation, Psychological↗
PubMed1992

The Language Research Center's Computerized Test System for environmental enrichment and psychological assessment.

In the spring of 1987, we undertook to provide environmental enrichment to nonhuman primate subjects in ways that would complement and even contribute to the bio-behaviorial science that justified the monkeys' captivity. Of course, the psychological well-being of captive primates--and indeed all research species-- has been an area of intense research activity since the 1985 amendment of the Animal Welfare Act. This mandate for researchers to ensure the psychological, as well as physical, fitness of experimental animals catalyzed the humane and scientific interests of the research community. The contemporary literature is replete with proposed means both of assaying and of providing enrichment and well-being. Notwithstanding, consensus on either assessment or intervention has yet to be reached. The paradigm we employed was modelled after successful efforts with chimpanzees. An automated test system was constructed in which subjects responded to computer tasks by manipulating a joystick. The tasks, interactive game-like versions of many of the classic testing paradigms of cognitive and comparative psychology, permitted the controlled presentation of stimuli and demands without the required presence of a human experimenter. Despite significant barriers to the success, rhesus monkeys (Macaca mulatta) and a variety of other primate species (including, of course, humans) have mastered the skills necessary for testing in this paradigm. Previous experiments have illustrated the utility of the test system for addressing questions of learning, memory, attention, perception, and motivation. Additional data have been reported to support the contention that the Language Research Center's Computerized Test System (LRC-CTS) serves its other raison d'etre--providing environmental enrichment and assessing psychological well-being. This paper is designed to augment previous descriptions of the technology and the paradigm for scientists and caretakers interested in environmental enrichment and performance assessment with primates.

Animal Welfare↗
PubMed1990

The NASA/LRC Computerized Test System.

A new testing package, including apparatus and tasks, is described for the study of behavior of a variety of species in a variety of experiments. The package is described with respect to the kinds of comparative psychological investigations for which it is well suited. The preliminary data generated within this new testing paradigm demonstrate that the NASA/LRC Computerized Test System provides a flexible yet powerful environment for the investigation of behavioral and psychological processes.

Animals↗
PubMed1989

Rhesus monkeys (Macaca mulatta), video tasks, and implications for stimulus-response spatial contiguity.

Recent reports (Iwai, Yaginuma, & Mishkin, 1986; Yaginuma & Iwai, 1986) have supported the earlier conclusion by Meyer, Treichler, and Meyer (1965) and by Stollnitz (1965) that the efficiency of primate learning is compromised to the degree that there is spatial discontiguity between discriminanda and the locus of response. The research reported in this article calls for a reconsideration of this conclusion. Two rhesus monkeys (Macaca mulatta) easily mastered precise control of a joystick to respond to a variety of computer-generated targets despite the fact that the joystick was located 9 to 18 cm from the video screen. We hold that stimulus-response contiguity is a significant parameter of learning only to the degree that the monkey visually attends to the directional movements of its hand in order to displace discriminanda as in the Wisconsin General Test Apparatus. If, instead, attention is focused on the effects of the hand's movement rather than on the hand itself, stimulus-response contiguity is no longer a primary parameter of learning. The implications of this work for mirror-guided studies are discussed.

Animals↗
PubMed1982

The feature-positive effect in adult humans: within-group design.

The feature-positive effect has been demonstrated in several species and has been shown to be robust phenomenon in adult humans when between-group designs are used. The present series of experiments replicated earlier work using between-group designs, found the feature-positive effect using within-group designs, and isolated a factor responsible for an earlier failure to find the phenomenon using a within-group design. The results support the argument for a biological, evolutionary influence in the genesis of the feature-positive effect.

Adult↗
PubMed1981

Stimulus stringing by pigeons.

Pigeons were trained to peck one, two, three, and then four colors in a predetermined sequence from a five-key array where, over trials, each color appeared equally often in each position of the array. Incorrect pecks resulted in a buzzer and trial termination, with the same array presented for the next trial. Correct pecks produced feedback and correct strings could produce food. All subjects performed at a high level of accuracy with no difference at asymptote between a continuous and a mixed spectral sequence as the required order. Transfer to a new set of arrays had little effect on accuracy. Errors forward in the sequence had the highest probability, followed by repeat errors, backward errors, and dark-key errors. Some arrays had a higher level of accuracy than others but a corresponding systematic variable could not be identified.

Journal Article↗
PubMed1978

Response suppression on DRL by rats with septal damage.

The effectiveness of the differential reinforcement for low rates of responding (DRL) contingency in suppressing response rates of septal rats was investigated by using a Multi-DRL-yoked-VI (variable interval) schedule of reinforcement. The yoking procedure equated the interreinforcement times on the two schedules. Each schedule was in effect for half of each session, and the change in schedule was signaled by the presence or absence of a cue light. Schedule order and DRL delay requirement were varied. For both normal and septal rats, the response rates were higher in the VI component than the DRL component; this effect demonstrates that the responding of septals as well as normals is suppressed by the differential reinforcement of a particular class of IRTs. A sharp difference in the level of responding occurred at the point of transition from one component of the multiple schedule to the other, which provides evidence of a discrimination between the two schedules for both normals and septals. The conclusion is that the responding of septals is suppressed by the DRL contingency and not controlled solely by the density and distribution of reinforcement.

Animals↗
PubMed1976

A comparison of the key-peck and treadle-press operants in the pigeon: differential-reinforcement-of-low-rate schedule of reinforcement.

Key pecking and treadle pressing in pigeons were compared under concurrent (key-treadle) and single-operant differential-reinforcement-of-low-rate schedules of food reinforcement ranging from 5 to 60 sec (concurrent procedure) or 5 to 120 sec (single-operant procedure). Under both procedures, the two operants followed the same general law: decreasing response rate and reinforcement rate and increasing number of responses per reinforcement as a function of increasing schedule interval. High correlations were found between key pecking and treadle pressing for the measures of response rate, reinforcement rate, and responses per reinforcement. Regression equations allowed the prediction of treadle pressing from key pecking. More bursting occurred in responding to the key, and key pecking showed a more precise temporal discrimination than treadle pressing. A test for sequential dependencies between key and treadle responses showed significant dependencies not only under the concurrent procedure but also in data created artificially by merging key and treadle sequences from different pigeons under the concurrent procedure and from the same pigeon under the single-operant procedure. It seems likely that the sequential dependencies found were due to the independent action of the schedule on each operant and that behavioral dependencies did not occur with the concurrent training procedure. The key-peck operant does not appear to have any special qualities that preclude its use in discovering general laws of behavior, at least under the differential-reinforcement-of-low-rate schedule. The usefulness of the key peck in other situations requires direct experimental study.

Journal Article↗
PubMed1975

The effect of the size of the test environment on behavior under two temporally defined schedules.

The effect of the size of the floor area of the operant test chamber on behavior was tested using a standard-size test chamber and a test chamber with one-fourth of the floor area of the standard chamber. Two groups of pigeons were tested under a differential-reinforcement-of-low-rate 15-sec schedule or a variable-interval 60-sec schedule. Both groups of pigeons had higher response rates while in the smaller floor area. Pigeons under the differential-reinforcement-of-low-rate schedule also showed a decrease in rate of reinforcement, an increase in ratio of responses to reinforcements, and an alteration in interresponse-time-per-opportunity distributions when tested in the reduced floor-area condition. These effects are similar to those found under physical restraint, indicating that amount of floor space available for locomotion interacts with schedule behavior and that physical restraint may be regarded as the lower limiting value of amount of floor area available for locomotion.

Journal Article↗
PubMed1974

The effect of physical restraint on behavior under the differential-reinforcement-of-low-rate schedule.

Previous studies have identified and manipulated collateral behavior to assess the effect of collateral behavior on performance under the differential-reinforcement-of-low-rate (DRL) schedule. However, conclusions could not be applied to subjects not observed to engage in collateral behavior. The present study used a technique that prevented the occurrence of the types of collateral behavior typically observed in the pigeon. This technique did not require the identification of collateral behavior in the subjects. The exclusion of the types of collateral behavior typically observed in pigeons resulted in higher response rates and lower reinforcement rates under large DRL values but had no effect at lower DRL values. It was concluded that collateral behavior is necessary for low response rates and high reinforcement rates under large DRL values.

Journal Article↗
PubMed1974

Behavior under large values of the differential-reinforcement-of-low-rate schedule.

Pigeons pecked a key and rats pressed a lever for food reinforcement under large values of the differential-reinforcement-of-low-rate schedule. Each subject was tested under 10 different schedule values ranging from 1 to 45 min and was exposed to each schedule value at least twice. The mean interresponse time and mean interreinforcement time increased with the schedule value according to power functions. Response-probability functions were computed for schedule values below 20 min and showed an increase in response probability as a function of time since the last response in most cases. Mean responses per reinforcer increased as a function of schedule value for the rats, but decreased as a function of schedule value for the pigeons. The proportion of responses with interresponse times shorter than 1 sec were an increasing function of schedule value for the pigeons, but did not vary as a function of schedule value for the rats.

Journal Article↗
PubMed1973

A test of the effectiveness of the differential-reinforcement-of-low-rate schedule.

Pigeons and rats were used in a yoked-control design that equated the reinforcement distributions of differential-reinforcement-of-low-rate and variable-interval schedules. Both a between-subjects design and a within-subjects design found response rate higher for the variable-interval schedule than for the differential-reinforcement-of-low-rate schedule, thus demonstrating the effectiveness of the differential-reinforcement-of-low-rate contingency. The interresponse-time distributions were unimodal for all subjects under the variable-interval schedule and bimodal for pigeons under the differential-reinforcement-of-low-rate schedule. The interresponse-time distributions for rats under the differential-reinforcement-of-low-rate schedule were also bimodal in three of four cases but the height of the modes at the shorter interresponse times were small in both absolute value and in relation to the height of the modes at the shorter interresponse times of the pigeons' distributions.

Journal Article↗
PubMedDate not supplied

Inactivation of firefly luciferase and rat erythrocyte ATPase by ultrasound.

Previous work in our laboratories has shown that, amongst other effects, irradiation of frog skin with low intensity ultrasound causes reductions in the chemical driving force of the short-circuit current. This indicated that either the Na/K dependent ATPase or ATP availability were being reduced. We measured the effect of ultrasound irradiation on ATP and NA/K-dependent ATPase from inverted erythrocyte ghosts and on firefly luciferin and luciferase activity. Our findings demonstrate that ultrasonic cavitation-induced sonochemical reactions were responsible for irreversible inactivation of luciferase and ATPase but had little or no effect on ATP and luciferin. We measured the levels of hydrogen peroxide generated by ultrasound under the conditions of our experiments and found that it could account for only part of the enzyme inactivation observed. Free radical scavengers/antioxidants were capable of fully protecting the enzymes from ultrasound-induced inactivation. These findings demonstrate that, in addition to hydrogen peroxide, free radicals generated by ultrasound are responsible for the effects.

Adenosine Triphosphatases↗