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Biomedical subjects

W Knöfler

Publications and source records attributed to W Knöfler.

29 records · Page 2Linked to original sources

[Biocompatibility of implants with and without fluorohydrocarbon glow-discharge polymer coating. 1. Histologic and semiquantitative estimation of subcutaneous reactions in guinea pigs].

The reaction of the subcutaneous tissue in guinea-pigs at implants of titanium, titanium/glow discharge polymer, Gisadent KCM (chromium cobalt molybdenum alloy), and Gisadent/glow discharge polymer was investigated by a semiquantitative method of informing character. The 4 tested materials were well-tolerated at which titanium caused the smallest reaction.

Animals↗

[Biocompatibility of implants with and without fluorohydrocarbon glow-discharge polymer coating. 2. Automated equidensitometric recording of tissue reactions].

A conclusion on the biocompatibility, the solubility, and the chronic toxicity of different implant materials showed the equidensitometric measurement of the capsular thickness in the environs of the implants by means of the electronic image interpretation equipment Densitron. The method, the results, and the advantages of the technique are described.

Animals↗

[Biocompatibility of implants with and without fluorohydrocarbon glow-discharge polymer coating. 3. Mathematical models of the subsiding processes of the tissue reaction].

The subsidence process of the tissue reaction was estimated by the thickness of the fibrous capsule as well as different histologic characteristics in dependence on the period after the implantation of 4 several implant materials. This subsidence process was fitted mathematically by an exponential function respectively a power function by means of the regression analysis. The power function described best the experimentally found curve. The correspondence, on principle, of the subsidence process of the fibrous capsula thickness on the one hand and the 9 histologic characteristics on the other hand could be proved. A standard valuation for subcutaneous tests is demanded which include the designation of the thickness of the fibrous capsula as well as characteristic cell type frequencies as histologic characteristics.

Animals↗