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Biomedical subjects

W Knoth

Publications and source records attributed to W Knoth.

At least 19 recordsLinked to original sources
PubMed2004

The Elbe flood in August 2002--occurrence of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans (PCDD/F) and dioxin-like PCB in suspended particulate matter (SPM), sediment and fish.

As a result of extreme precipitation in August 2002 major flooding occurred in the catchment area of the rivers Elbe, Vltava (Moldau) and Mulde. Pollutants from industrial sites and from municipal sewage treatment works (STW) entered the Elbe and led to a serious pollution problem in the river. PCDD/F concentrations (in pg WHO-TEQ/g dw) in SPM ranged from 7-150, in sediments from 3-140; the "safe sediment value" of 20 was exceeded in 46% of the samples. 24 eels showed a wide concentration variation for these contaminants. The WHO-PCDD/F+PCB-TEQ values lay in the range from 11-56 pg/g ww, whereby the WHO-PCB-TEQ values were several times higher than the WHO-PCDD/F-TEQ values. The maximum permitted value of 4 pg WHO-PCDD/F/g ww (EU Directive No. 2375/2001) was reached or exceeded in 54% of the individuals. A statistical analysis using data from SPM and sediment samples showed that in the Czech river section the flooding activated a contamination source in the vicinity of the Spolana works. The influence of the tributary Mulde could be clearly demonstrated. Only a major clean-up of the contaminated sites in Bitterfeld can lead to a mid to long term improvement in respect of PCDD/F and dioxin-like PCB input into the Elbe.

Animals↗
PubMed1979

[Differential diagnostic studies using the dermatoscope in selected diseases].

The Zeis dermatoscope can be used beyond its known applications for precise and detailed skin surface examinations of different types of dermatosis. Differential diagnostic problems are solved by comparative observation of efflorescence and efflorescence fields of similar appearance. The examination series presented, the results of which are discussed in detail, is concerned mainly with surface examinations of parapsoriasis en plaques, seborrhea en plaques and the clinically similar early forms of mycosis fungoides. Also mentioned are examinations of lichen sclerosus et atrophicus and circumscribed scleroderma, lichen planus, Hutchinson-Dubreuilh freckle and similarly appearing facial verruca seborrhoica, as well as fresh dispersions of foreign bodies. The didactic value is underlined by color photographs taken of diseased skin and nails with the dermatoscope at various magnifications. Finally, a description is given of possible instrument extensions.

Dermatitis, Seborrheic↗
PubMed1977

[Fibrin depostition in granuloma anulare (author's transl)].

In 6 cases of granuloma anulare direct immunofluorescence studies were carried out with anti-fibrinogen and anti-immunoglobulin sera. Fibrin deposition was found in all lesions. The result is discussed with reference to local fibrinolysis.

Adolescent↗
PubMed1977

[Onychomycosis].

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Humans↗
PubMed1976

[Problems in the special nosological position of keratoacanthoma. Clinical, histological and comparative Feulgen-cytophotometric studies. 3. Classification of keratoacanthomas, therapeutic consequences, conclusions].

Feulgen-cytophotometric examinations of 61 keratoacanthomas of the skin have revealed 3 types differing from each other in their DNA distribution. Keratoacanthomas type I are characterized by a diploid DNA distribution--comparable to epidermis cells. An increasing average DNA content (x) and mean distribution (Sx) compared with diploid cells are, however, conspicuous. Keratoacanthomas type II display DNA peaks in the triploid phase and increasing x and Sx. Keratoacanthomas type III show DNA tumor stem lines in the hypotetraploid, tetraploid and hypertetraploid phases, with x and Sx further increasing. The occurrence of two tumor cell populations of aneuploid localization is noteworthy in part of the keratoacanthomas. Transitional types among the tumors mentioned above are possible. Only type I does not allow cytophotometric demarcation of epidermis cells or tissue lymphocytes based on statistical analysis. The three types of keratoacanthomas can be significantly defined against each other. These cytophotometric findings explain the occurrence of clinical variations of keratoacanthomas with tumor ulceration, increased growth and recidivity. As a rule total excision and careful histological examinations are advisable. The occurrence of paraneoplastic keratoacanthomas and carcinomata disguished as keratoacanthomas is mentioned. Spontaneous healing should not be waited for despite the possible occurrence of benign keratoacanthomas.

Aged↗
PubMed1976

[Granulomas of axillae (zirconium?) (author's transl)].

Deodorant preparations containing Zirconium may induce axillary granulomas of allergic origin. The case of a 49 years old female patient is presented, who developed axillary granulomas after having used a deodorant preparation containing Zirconium.

Axilla↗