Biomedical subjects

W Korp

Publications and source records attributed to W Korp.

18 recordsLinked to original sources

PubMed1977

[Diabetes and pregnancy: treatment and results (author's transl)].

Pregnancy and delivery in 190 diabetic women are described. Obstetric, medical and neonatal guidelines for treatment are outlined and the following results are reported: 1. The delivery dates suggested by P. White were generally exceeded by 2 weeks. Group A was delivered at term, group B generally in the 38th week, group C between the 37th and 38th week and group D mostly in the 37th week of gestation. 2. Spontaneous delivery was achieved in 60% of the cases; Caesarean section was necessary in 33%, whilst the incidence of vacuum extraction was 5%. 3. The perinatal infant mortality rate in diabetic pregnancy decreased from 22.9% in 1970/71 to 2.7% in 1972/1976. 4. Perinatal mortality was related to the degree of severity of diabetes according to White's classification. 5. The percentage of PBSP cases was lowered from 32% to 24%. Perinatal mortality in the PBSP group decreased from 50% in 1970/71 to 19% in 1972/1976. 6. Hypoglycaemia occurred in 70% of 74 newborn infants submitted to intensive neonatal care. A true glucose value of less than 25 mg% was recorded in 30% of these cases. Hypocalcaemia was present in 16% cases, whilst 62% of the newborn infants suffered from respiratory distress syndrome. Cardiomegaly occurred in 28% of infants. 7. Development and prognosis are judged to be favourable in children of diabetic mothers.

Austria↗

PubMed1977

[Diabetic coma: incidence of infections and mortality (author's transl)].

An analysis of 752 cases of severe diabetic coma during the period 1931 to 1973 showed that infections were present in one or more organs in 58% of the cases. The incidence of infections showed an increase from 53% (1931 to 1940 to 57% (1961 to 1970), with a further rise to 61%(1971 to 1973). A decrease in pulmonary infections from 40% to 17% and a distinct increase in urogenitial tract infections from 6% to 20% and in multiple infective complications from 3% to 7% were the most striking findings. The incidence of infections in other organs (abdominal, dermatological, laryngological and miscellaneous) remained virtually constant over the individual decades. Mortality was altogether higher in patients with infections (30% versus 20% in patients without infections). The highest mortality (35%) was recorded in the period 1951 to 1960; THE latest figure was 29%(1971 to 1973). Antibiotics are presumeably responsible for the decrease in the initially high mortality rate of 41% to 50% in urogenitial tract infections to 23% for the decade 1961-1970, with a further drop to 18% in the most recent period (1971 to 1973). Similarly, with multiple infections the mortality of 100% up till 1950 decreased to a recent figure of 63%, partly on account of the introduction of intensive care therapy during the past years. In abdominal infections there was also a distinct decrease in mortality form 43% to 14%, whilst in pulmonary infections the mortality remained at about the same level (24% to 28%).

Anti-Bacterial Agents↗

PubMed1975

[Diabetic coma. A report of 752 cases between 1931 and 1973].

752 diabetic comata (150 non-ketoacidotic and 602 ketoacidotic) from the period between 1931 and 1973 were investigated with regard to type of coma, age, sex, blood sugar, body type, previous therapy, presence of infections and their location and lethality. The blood sugar rose from 521 mg percent in the period from 1931-1940 to 701 mg percent in the period from 1971-73, and age from 33.9 to 53.7 years. Patients without ketoacidosis had higher blood sugar and were older than those with ketoacidosis. Lethality was higher in women than in men. Mortality was higher with obesity (28.8 percent compared to 20.1 percent). 23.9 percent of them were "manifestation" comata of which 43.1 percent died. The lowest lethality was found in the 453 diabetics who had been treated with insulin (14.6 percent). Infections were demonstrable in 431 patients (57.3 percent). Of these, 30.1 percent died, of patients without infections 19.6 percent died. Mortality was 74.6 percent where infections were present in two or more organs.

Adult↗

PubMed1973