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Biomedical subjects

W Kuźna-Grygiel

Publications and source records attributed to W Kuźna-Grygiel.

8 recordsLinked to original sources
PubMed1997

[A case of imported human babesiosis in Poland].

The first cae of human babesiosis in Poland imported from Brazil were ascertained in our Department. Diagnosis was based on hamster inoculation by intraperitoneally injection of patient's blood. In Giemsa stained erythrocytes characteristic forms of Babesia microti were detected.

Adult↗
PubMed1996

[Cytochemical study on the activity of enzymes in trophozoites of Entamoeba histolytica from the cecum of guinea pigs with invasive and non-invasive amebiasis].

Experimental amoebiasis was inflicted on guinea pigs using the PS-2 strain of Entamoeba histolytica. Cytoenzymatic studies were conducted on the trophozoites sampled from the caecum of hosts with non-invasive and invasive amebiasis. The results show higher intensity of the processes of intracellular digestion, transportation, and anaerobic respiration in the amoebae originating from intestine of the host with infective amoebiasis.

Acid Phosphatase↗
PubMed1995

[Histological and histochemical investigations of large and small intestine in guinea pigs infected by entamoeba histolytica].

In order to gain better knowledge about pathomechanisms of amebiasis, histological and histochemical studies were performed on large and small intestine of guinea pigs infected by PS-2 Entamoeba histolytica strain. Results of these studies showed that the presence of E. histolytica in large intestine caused also pathomorphological changes of small intestine: partial atrophy of villi, epithelium destruction, epithelial metaplasia, lacteral dilation, infiltration of mucous membrane by lymphocytes, plasmocytes and macrophages. Influence of this parasite on lowering of investigated enzyme reactions and reduction of mucus secretion in large intestine as well as in small intestine of infected animals were also shown. These results suggest influence of E. histolytica cytotoxins (studied earlier by others authors) on the enzymes activity in host tissues and next on the weakness of intracellular metabolism and on cells destruction. For induction of these changes the adhesion host cell-amoeba is not necessary.

Animals↗
PubMed1993

Assessment of the nasal mucosa in workers exposed to the prolonged effect of phosphorite and apatite dusts.

One hundred and thirty one workers occupationally exposed to phosphorite and apatite dusts and a control group underwent repeated laryngological and cytological examinations of nasal mucosa smears. The clinical examination showed chronic simple or atrophic rhinitis. The cytological test revealed metaplasia of the respiratory epithelium towards squamous epithelium in all smears. Both the rate of catarrhal changes and the degree of epithelial metaplasia varied with the duration of exposure.

Adult↗
PubMed1980

Activity of some respiratory and lysosomal enzymes of lymphocytes in golden hamster with induced melanoma.

A considerable increase in activity of the following enzymes: succinate dehydrogenase (SDH), lactate dehydrogenase (LDH), beta-hydrogenase (beta-HBDH), cytochrome oxidase (CO), and acid phosphatase (AP) was found in lymph nodes lymphocytes after 1 week of malignant melanoma passage in golden hamster (Mesocricetus auratus Waterhouse). The peripheral blood lymphocytes displayed, too, an increase in activity of all the enzymes mentioned except beta-HBDH and SDH. After 3 weeks of the melanoma growth, the animals affected showed a considerable decrease in activity of all the enzymes studied both in the lymph nodes and in the peripheral blood. The increase in enzymatic activity during the initial phase of tumour growth may be a manifestation of biological activation of the cellular defence of lymphocytes. On the other hand, the decrease in the activity seen at the advanced phase of the disease speaks for an impaired immune response.

Acid Phosphatase↗