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Biomedical subjects

W Kuhnert

Publications and source records attributed to W Kuhnert.

6 recordsLinked to original sources
PubMed1988

[Initial results of genetic carrier diagnosis in risk pedigrees with hemophilia A and B in East Germany].

In 7 families at risk for hemophilia A 42 individuals were evaluated by the Taq I polymorphism of the extragenic probe St 14.1 and the Bcl I as well the Hind III polymorphism of the intragenic probe F8e16-19. 15 out of 20 females of the core families were identified as carriers, under them all of the obligate heterozygotes. 5 individuals were excluded as carriers. The heterozygosity for each of the RFLPs was found to be between 30% and 79%. Combining the single data in 96% heterozygosity was found under the individuals tested. A linkage disequilibrium was found between the Bcl I and Hind III polymorphismus of the probe F8e16-19. A family at risk for hemophilia B including 5 individuals was studied using the Taq I and Xmn I polymorphisms of the probe P1. In one of two females the carrier state could be excluded in the other one confirmed.

Genetic Carrier Screening↗
PubMed1986

[Noninvasive roentgen diagnosis of right heart function in patients with recirculation disorders and chronic nonspecific lung changes].

The non-invasive x-ray functional diagnostic electroradiographic method at the large vessels near the heart may enrich the radiological preliminary diagnostics of recirculation abnormalities. In chronic unspecific pulmonary diseases it can characterize the load of the right heart. Our studies should serve as a pilot study for the in future possible, simply to be handled non-invasive video-densitometry of the vessels near the heart in the preliminary diagnostics of cardiovascular diseases.

Cardiac Output↗
PubMed1985

[Results of long-term conditioning in patients with myocardial infarction during phase III rehabilitation].

The active kinesitherapy is an essential constituent of the whole rehabilitation process of patients with infarction. Despite the decrease due to the physiology of ageing and the progression of the coronary disease the physical functional capacity can be kept relatively constant also over many years. Thus the quality of the patients' lives can be favourably influenced. Whether the life expectancy alone can be improved at long date by the active conditioning, further on remains unclarified. Aimed differentiated medication, psychosocial measures, the consideration of secondary bronchopulmonary diseases and the well-timed selection for the coronary-surgical intervention must be included into the process of complex rehabilitation of patients with myocardial infarction. In these cases diagnostics and therapy of the somatic risk factors must particularly be taken into consideration during the whole process of rehabilitation in order to decrease the progressing of the basic disease.

Adult↗