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W L Bostick

Publications and source records attributed to W L Bostick.

6 recordsLinked to original sources
PubMed1982

Third report of the ASCP/CAP/APC joint task force on pathology manpower.

This report concerns the results of pathology manpower surveys encompassing responses from four groups of pathologists: (1) solo and group practitioners; (2) training program directors; (3) house staff; (4) diplomates seeking positions. The rate of response by all four groups is judged highly satisfactory. The results show an approximate balance between supply and demand with respect to manpower in pathology. Comparison with the results of two similar surveys conducted by the Joint Task Force shows the following trends: (1) a continued marked reduction of foreign medical graduate (FMG) trainees; (2) continued increase in the proportion of women entering pathology; (3) an increase in the size of the average practice and a corresponding decrease in the proportion of pathologists in solo practice; (4) a decreased tendency of practicing pathologists to relocate; (5) an increase in pathologists lost to the profession because of death, disability and retirement; (6) a slight decrease (approximately 50) in the number of funded full-time positions and a slight increase in the number of part-time vacancies.

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PubMed1977

Preleukemic change in the bone marrow of whole-body irradiated RFM/Up mice.

In the whole-body irradiated mouse, various late effects of radiation are observed after the recovery from acute radiation injury. Some of these account for the familiar proneness of certain mouse strains to develop leukemias. The two experiments described below were designed to (a) identify such preleukemic changes in blood-forming tissues and (b) to find ways to manipulate them experimentally with the purpose of preventing leukemia. Preleukemic change of the bone marrow appears to be a mere quantitative departure from normal in a qualitatively non-malignant tissue. It entails increased proneness of immature (precursor) cells to react with latent virus. Our data are consistent with the assumption that this proneness is enhanced (or brought about) by removal of a controlling influence exerted by the mature cells over their precursors (feed-back inhibition). Re-irradiation combined with intravenous bone marrow substitution offsets the leukemogenic influence of an earlier radiation exposure. The effect of re-irradiation on bone marrow displaying preleukemic lesions corroborates conclusions from earlier experiments on the nature of these lesions.

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