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Biomedical subjects

W L Burt

Publications and source records attributed to W L Burt.

8 recordsLinked to original sources
PubMed1992

Fluorescent viscoelastic enhancement.

By inserting an Erreger 485 exciter filter into the operating microscope, translucent yellow Healon (sodium hyaluronate) transforms into a brilliant opaque green viscoelastic. We have developed this technique and termed it "fluorescent viscoelastic enhancement." Using the technique, we demonstrated that the time required to remove Healon from the anterior chamber after intraocular lens insertion varies. Healon is usually aspirated quickly, in less than 17 seconds. Otherwise it traps behind the intraocular lens and requires more time for irrigation/aspiration (I/A) and manipulation of the I/A tip. Fluorescent viscoelastic enhancement minimized I/A time, reducing excess turbulence and manipulation in the anterior chamber, and thus may reduce corneal endothelial cell loss. This study also demonstrated that fluorescent viscoelastic enhancement prevented postoperative intraocular pressure rise, compared to the conventional removal of clear Healon. Fluorescent viscoelastic enhancement assures the surgeon that a large amount of Healon is not left behind.

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PubMed1991

Primary localized amyloidosis of the lacrimal glands.

Primary localized amyloidosis causing bilateral lacrimal enlargement is rare. The pathogenesis of amyloid deposition within the orbit and other body tissues has not been fully elucidated. The authors report the case of a 72-year-old woman who presented with bilateral lacrimal gland enlargement secondary to amyloid infiltration. The chemical nature of the deposit was characterized using light microscopy, immunohistochemistry, and immunoelectron microscopy. The primary (immunocytic) nature of the amyloid was confirmed by immunohistochemistry demonstrating the presence of monoclonal lambda light chains in the amyloid deposits and in the plasma cells. Using immunoelectron microscopy, amyloid deposits were seen containing lambda light chains in macrophages. It has been postulated that the macrophage has a role in amyloid deposition. The authors believe this to be the first published report of immunoelectron microscopy use in orbital amyloidosis, and that this technique has helped further their understanding of the nature and pathogenesis of this condition.

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