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Biomedical subjects

W L Furlow

Publications and source records attributed to W L Furlow.

At least 55 records · Page 3Linked to original sources
PubMed1980

Primary grade 1 transitional cell carcinoma of the renal pelvis and ureter.

During a 22-year period 224 patients were seen for treatment of transitional cell carcinoma of the renal pelvis or ureter. Of these patients 49 (22 per cent) had grade 1 lesions. Followup ranged from 5 to 25 years. The most common symptom was hematuria. In only 54 per cent of the 49 patients was a filling defect noted on excretory urography. Forty-seven patients (96 per cent) had stage I disease. Treatment included total nephroureterectomy, nephrectomy or segmental resection. In 11 patients (23 per cent) evidence of bladder tumor developed 8 months to 12 years (average 4 years) after the diagnosis of tumor of the upper urinary tract and 73 per cent of these recurrences were noted within the first 3 years. In 1 patient a tumor developed in the opposite upper urinary tract. In only 1 of 15 patients who had had partial ureterectomy or local excision tumor developed in the ipsilateral ureter. Patient survival time was identical to that in an age-matched control group. We conclude that the most significant findings are the subsequent high incidence (23 per cent) of bladder tumor and the comparable survival in these pateints and in an age-matched control group. Furthermore, these results suggest that operations preserving the renal parenchyma, that is segmental resection, should be used more frequently.

Carcinoma, Transitional Cell↗
PubMed1979

Inflatable penile prosthesis: Mayo Clinic experience with 175 patients.

Sex prosthetics have become an established alternative of therapy for both the organically and the psychogenically impotent male patient. Functional success with the implantation of the inflatable penile prosthesis can be anticipated in 90 to 95 per cent of the patients. Both mechanical and pathologic complications occur, but with relatively low frequency. There have been no reported operative or postoperative deaths associated with the implantation of more than 6,000 devices. The availability of penile prostheses to impotent patients should be limited only by the patient's ability to meet the rigid criteria for selection of patients. When these criteria are fulfilled and the patient's expectations are in harmony with the known results that can be provided by implantation, uniformly successful results can be expected.

Adult↗
PubMed1979

Inflatable penile prosthesis: follow-up study of patient-partner satisfaction.

The surgical success rates using implantable penile prostheses are well documented, although follow-up on their functional success is required. In this study of 175 patients with an inflatable penile prosthesis, patients and their partners were evaluated as to patient-partner satisfaction, levels of satisfaction, causes of dissatisfaction, frequency of intercouse, and over-all acceptance of the device by patient and partner. The initial satisfaction rates of 79 per cent were significantly improved to 89 per cent after management of specific unrecognized complications. The high levels of satisfaction found in this study continue to support our guidelines for device selection and implantation.

Coitus↗
PubMed1978

Inflatable penile prosthesis: new device for cylinder insertion.

A new device for insertion of inflatable penile cylinders into the corpus cavernosum significantly simplifies the implantation of the inflatable penile prosthesis. Use of this device assures accurate positioning within the corpora, with a minimum of device manipulation and tissue trauma, thereby minimizing postoperative complications.

Erectile Dysfunction↗
PubMed1978

The current status of the inflatable penile prosthesis in the management of impotence: Mayo Clinic experience updated.

During the last 2 years the inflatable penile prosthesis has been implanted at the Mayo Clinic in 63 organically impotent male subjects. Over-all functional success is between 90 and 95 per cent. Experience indicates that 25 per cent of the patients require a second surgical procedure to correct a mechanical problem. Further experience with the technique and improvement in the product design have significantly decreased the number of mechanical problems encountered. Patient partner acceptance of this device continues to be excellent.

Erectile Dysfunction↗
PubMed1978

Surgical management of impotence using the inflatable penile prosthesis: experience with 103 patients.

The inflatable hydraulic penile prosthesis has been implanted in 103 patients with both organic and psychogenic impotence. The 4 failures in this series resulted from infection. Mechanical problems occurred in 27 patients, but with additional implant experience, these have been significantly induced. All mechanical complications are correctable through secondary and tertiary surgical procedures. Ninety-eight of 99 patients with a normally functioning prosthetic device had satisfactory intercourse without significant difficulty. The inflatable penile prosthesis has improved to be a highly satisfactory method of treating male impotence.

Adult↗
PubMed1976

Nephropexy: fact or fiction?

At the Mayo Clinic, from 1940 through 1974, 21 patients have undergone nephropexy for nephroptosis. Fourteen of the 16 patients with long-term follow-up were cured; 2 of the 16 patients were partially relieved. An additional 2 patients who had one-year follow-up examinations were asymptomatic. Three patients were lost to follow-up. In this series results with the various methods of fixation did not differ, and results in patients who retained their normal position postoperatively as compared with those whose kidneys reverted to their preoperative level also did not differ. Patients who had psychologic disorders fared as well as those who did not. Greater use of renography probably could be made in the assessment of symptoms. Although this review does not suggest that nephropexy for primary nephroptosis be restored to its former appeal of the 1930s, we suggest that its use be considered again in urologic surgery.

Adolescent↗
PubMed1976

Transpubic urethroplasty.

Eleven patients underwent transpubic repair of membranous urethral strictures. Excision of the wedge of pubic bone was not associated with orthopedic disability and provided excellent exposure for primary anastomosis of the urethra. Distal urethral mobilization and incision of the intercrural septum provided adequate urethral length for tension-free anastomosis. Satisfactory results were achieved in all patients, without adversely affecting continence or potency.

Adolescent↗
PubMed1976

The surgical fate of ureteral calculi: review of Mayo Clinic experience.

A review of 1,061 patients who underwent ureterolithotomy of transurethral manipulation revealed 2 factors that are important to consider; 1) the roentgenographic size of the calculi measured at the largest diameter and 2) the location of the calculus. These 2 facotrs in addition to the general medical condition of the patient, the duration of severity of symptoms and the status of the upper urinary tract provide suitable guide lines for individual management of ureteral calculi.

Adolescent↗
PubMed1976

Surgical management of impotence using the inflatable penile prosthesis. Experience with 36 patients.

Inflatable hydraulic penile prostheses were implanted in 36 patients who had organic impotence. Selection of patients was based on a series of guidelines that included the historical aspects of the patient's initiative, acceptance of the device by patient and partner, motivations, and psychiatric evaluation. Minor complications after implantation were not associated with the ultimate successful function of the device. Major complications were mainly mechanical in origin and readily corrected by secondary surgical procedures. The single failure in this series was associated with infection around the prosthesis, which necessitated removal of the entire device. A nearly physiologic erection was produced in 375 patients. Functional application of the implanted device was successfully achieved in 34 of 35 patients who retained their device. Patient-partner acceptance has been excellent.

Adult↗
PubMed1976

The implantable artificial genitourinary sphincter in the management of total urinary incontinence.

The artificial genitourinary sphincter has been implanted in 31 patients with total urinary incontinence. Minor complications associated with implantation of this device were found to be mainly mechanical in origin, resulting in malfunction of the apparatus. Postoperative mechanical malfunction, however, was found to be correctable through a variety of secondary surgical procedures. Major complications, including infection around the prosthesis, vesical neck erosion, vesical-colic fistula, and urethral erosion, were generally associated with problems of cuff placement. In nearly all cases in which major complications occurred, it was ultimately necessary to remove the prosthesis. Overall results would indicate that patients with incontinence after transurethral prostatic resection in whom the inflatable cuff was placed around the vesical neck achieved the best results (70%). In this series of 31 patients, 68% had a normally functioning sphincter with complete correction of their urinary incontinence.

Animals↗
PubMed1976

The effect of intravesical formalin on the destruction and regeneration of the canine bladder.

Instillation of cytotoxic compounds into the bladder elicits an effect that is based on contact of the agent with the mucosal cells. In the female dog, the distribution of this contact is characteristically in the lower portion of the bladder, and the dome of the bladder is almost invariably spared. Study with formalin indicates that the amount of mucosal contact is best increased by distention of the bladder to full capacity. These findings have significance in the use of topically active agents for the treatment of bladder cancer.

Animals↗
PubMed1975

Peyronie's disease: a study of its natural history and treatment with orthovoltage radiotherapy.

Followup data on 90 of 177 patients with Peyronie's disease seen from Janurary 1, 1950 to April 1, 1970 revealed that the ultimate outcome of the disease when not treated was no different from that following orthovoltage radiotherapy. The real benefit derived from orthovoltage radiotherapy appears to be that it hastens symptomatic improvement by 3 to 7 months. In 21 per cent of the patients there was an associated inflammatory joint or tendon disease, an association not previously reported.

Follow-Up Studies↗