Carbocisteine polymorphism and disease.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to W L Gregory.
Explore the source record for details and available documents.
Previous studies linking heterosexual activity to women's menstrual cycle variability have failed to take into account the effects of gynecological maturity. One hundred thirty-two women, all at least seven years postmenarche and not using birth control pills, completed daily records of their cycles and their heterosexual behavior. Data from women classified as sexually celibate or as regularly sexually active (having sex at least once per week in every nonmenstruating week) replicated previous findings while controlling for gynecological maturity: Women classified as celibate had more variable cycles than women who engaged regularly in heterosexual activity. An interaction between gynecological maturity and sexual status was also found, precluding a comparison involving women who were sexually active on an irregular basis. The interaction revealed that increased gynecological maturity is associated with less variable cycles in the sexually sporadic women, but is not associated with cycle variability in either celibate or sexually regular women. Possible biological mechanisms for these findings and their implications are discussed.
Ascertained if being a member of a statistical minority influences children's adjustment in school, as measured by the AML, a teacher-administered adjustment rating scale. Teachers from a southwest school district evaluated elementary students on aggressive, acting-out behaviors, moody-internalized behaviors, and learning difficulties. Analyses conducted on 376 students revealed significant effects of statistical minority status on certain dimensions of adjustment ratings for both Hispanic and Anglo students. Hispanic students in the statistical minority received poorer ratings on the moodiness dimension of the AML than nonminority Hispanic students. Anglo students in the statistical minority received poorer ratings on the aggression dimension of the AML than nonminority Anglo students. These results were interpreted in terms of cultural differences in coping with statistical minority status. Traits commonly exhibited within a culture may intensify and be perceived as maladaptive when stress resulting from being a minority occurs. Implications of the finding that statistical minority status within the school environment influences adjustment are discussed.
Female undergraduates (n = 62) who scored as extreme internals or externals on the Mirels Personal Fate Control Scale participated in a partial replication of Hiroto's learned helplessness experiment. Lights were added to the treatment apparatus, which made explicit to subjects the contingency or noncontingency between their responses and the termination of an aversive tone. As predicted, the performance of internals was significantly impaired by uncontrollability (learned helplessness), while that of externals was facilitated by controllability (learned effectiveness). Externals performed as well as internals in the "escapable" condition, but their performance was inferior to that of internals in the control condition. Following "inescapable" treatment, internals performed worse than externals. These results are supportive of Lefcourt's theory of cue explication. Implications for locus of control and learned helplessness research are discussed.
Explore the source record for details and available documents.
The dually diagnosed patient with attention deficit disorder, residual type (ADD-RT) may be especially prone to cocaine abuse, because ADD includes dopamine deficiencies and cocaine is a dopamine agonist. It is hypothesized that bromocriptine, a dopamine agonist, will reduce a patient's craving for cocaine and simultaneously address the patient's ADD-RT symptoms. A single-organism, double-blind research design is used to evaluate the efficacy of bromocriptine, as measured by scale 9 of the MMPI, the digit span and digit symbol tests of the Wechsler Intelligence Scale-Revised, and the signaling to numbers test. Statistical analysis of the results revealed an equivocal response to bromocriptine.