PubMed Health⌕ Search

Biomedical subjects

W Lawkowicz

Publications and source records attributed to W Lawkowicz.

52 records · Page 3Linked to original sources
PubMedDate not supplied

[Spontaneous nitroblue terazolium reduction test (NBT) by peripheral blood granulocytes in healthy subjects and in some hematologic syndromes].

The NBT reduction test and determination of alkaline phosphatase activity in the peripheral blood granulocytes (FAG) were done in 94 subjects including 30 blood donors donating blood for the first time and 64 cases of various haematological syndromes. Raised proportion of formazan granulocytes was found in patients with pancytopenia, acute myeloid leukaemia, chronic myeloid leukaemia during blastic exacerbation, Hodgkin's disease during exacerbation and lymphosarcoma. These results correlated with increased FAG activity. Lower proportions of formazan granulocytes capable of spontaneous reduction of NBT were found in patients with chronic myeloid leukaemia, in immunohaemolytic anaemias and in plasmocytoma. Of all the above syndromes only in chronic myeloid leukaemia impaired ability of formazan cell formation parallelled decreased FAG activity. In the remaining syndromes FAG activity in the granulocytes was normal or raised. In the remissions of Hodgkin's disease a fall was observed in the proportion of formazan granulocytes to values of FAG. In chronic myeloid leukaemia the proportion of formazan cells showed considerable fluctuations and no correlation was observed between the proportion of formazan cells and FAG activity.

Alkaline Phosphatase↗
PubMedDate not supplied

[4-year-observation of results of VM 26 treatment of pathologic syndromes from the lymphoma malignum group].

The authors used the preparation VM 26 in 66 patients with various pathological syndromes belonging to the group of malignant lymphoma. The patients were divided into three groups. Group A received only VM 26, group B VM 26 and ultracorten, group C VM 26, cyclophosphamide, methylhydrazine and glycocorticosteroids. In all observed groups a therapeutic activity of VM 26 was demonstrated. The best therapeutic results were obtained in group C, in group B they were slightly worse.

Adult↗
PubMedDate not supplied

Differences in the composition of leucoyctes in the splenic artery and vein in rabbits, and dogs.

Differences in the composition of leucocytes in the splenic artery and vein in rabbits, and dogs. Acta Physiol. Pol. 1975, 26 (1): 33-39. Blood samples were taken from the splenic artery and splenic vein of 14 rabbits and 9 dogs under general anaesthesia (with hexobarbital sodium in rabbits and Eunarcon in dogs) to compare the quantitative and qualitative composition of white blood cells. It was found that the rabbit spleen releases into the circulation mononuclear cells which do not differ in their size from cells of the blood flowing into the spleen, and that it can retain or release granulocytes, probably due to their intravascular margination. The dog spleen can retain or release granulocytes and mononuclears simultaneously or separately, probably due to the mechanism which includes spontaneous contraction of the spleen.

Animals↗
PubMedDate not supplied

[Lysosomes of blast cells in various cytochemical types of acute leukemia].

In 25 cases cytochemical types of acute leukemia were determined using the classification of Loeffler. Three cytochemical methods used were: p.a.S.-glycogen content, pox-peroxidase activity, and esterase activity determinatione. At the same time selective identification of lysosomes in perypheral blood blast cells was done using vital euchrisine staining and fluorescence microscopy. A correlation was observed between the cytochemical types of acute leukaemia and the lysosomal pattern. The fluorescence method of the identification of lysosomes is suggested for diagnosis of acute leukaemia.

Acute Disease↗