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Biomedical subjects

W Lechner

Publications and source records attributed to W Lechner.

At least 73 records · Page 4Linked to original sources

Correlation of oestriol levels in saliva, plasma and urine of pregnant women.

Unconjugated and total oestriol (E3) have been determined in saliva (S) and plasma (P) by radioimmunoassay using a highly specific antiserum against E3. Total oestrogens (E = E1 + E2 + E3) in urine were analysed by the Kober-Ittrich method. No correlation (P greater than 0.05) was found between unconjugated E3 (S) and total E (U) as well as total E3 (S) and total E (U). Total E3 (S) and unconjugated E3 (P), total E3 (S) and total E3 (P) correlated weakly (P less than 0.05 and greater than 0.01). The six remaining correlations were highly significant (P less than 0.001 or less than 0.0001).

Estriol

[Hand-foot-mouth disease].

A case of hand-foot-and-mouth disease is reported in a 20-year-old female patient. Infection by Coxsackie A 16-virus was diagnosed by serology.

Adult

[Eccrine spiradenoma].

Eccrine spiradenomas are rare and usually painful tumours, but most textbooks and reviews contain no photographs of typical cases. Therefore we report on this tumour and document our report with clinical photographs.

Adenoma, Sweat Gland

[Stimulation of ovulation by follicular puncture].

We report on a patient with long-standing sterility, who became pregnant only after laparoscopic puncture of the follicle in spite of all possible diagnostic and therapeutic procedures being applied. The methods so far used for stimulation of ovulation are discussed and the puncture of the ovary is proposed as new possibility in the treatment of sterility.

Adult

Epidermodysplasia verruciformis in lepromatous leprosy. Report of 2 cases.

2 African patients (sisters) suffering from lepromatous leprosy had epidermodysplasia verruciformis. Both patients had in addition recalcitrant superficial fungal infections and extensive relapsing scabies. The question is raised whether a generalized impairment of cell-mediated immunity, found in lepromatous leprosy, predisposes towards other particularly viral infections.

Adult

[Analysis of residues of the fungicide cymoxanil in grapes using multicolumn HPLC].

Residues of the contact fungicide Cymoxanil in grapes were determined by a multidimensional multicolumn high pressure liquid chromatography technique (MC-HPLC). The sample pretreatment is a simple water extraction. Further clean-up and trace enrichment of an aliquot of the aqueous acidic sample solution is performed on-line via an automatized microprocessor controlled MC-HPLC system. In the range of 0.05-2.0 mg/kg grapes good linearity is achieved. Recoveries of Cymoxanil added to untreated grapes range between 70% and 80% at 0.05 and 2.0 mg/kg values, respectively, with a reproductibility of s +/- 3% at 0.2 mg/kg (n = 5). The total time for analysis is approximately 30 min.

Acetamides

[Focal epithelial hyperplasia in lepromatous leprosy].

Focal epithelial hyperplasia Heck (FEH) is most likely caused by human papilloma virus. It mainly occurs in children and young people showing no associated diseases. For the first time, we describe a case of FEH in a patient with lepromatous leprosy who due to persistent erythema nodosum leprosum has been treated with a lang-term glucocorticoid therapy. The question of the competence of lepromatous patients in resisting certain viral infections arises.

Adult

Histiocytosis-X in gynecology.

(1) Histiocytosis-X can manifest itself in virtually every organ, but in gynecology it is an absolute curiosity. (2) Differential diagnosis must exclude specific and nonspecific ulcerations and granulations such as syphilis, tuberculosis, Boeck's disease, and also neoplastic processes like lymphomas, sarcomas, carcinomas, and malignant diseases of the hemopoietic system. (3) The diagnosis by light microscopy alone, as in our case, may be insufficient; therefore, electron microscopy should be used. As soon as the diagnosis is confirmed histologically, an extensive examination of all organs is necessary in order to establish an exact prognosis and an optimal plan of therapy. (4) Because of the unknown etiology of histiocytosis-X, a causal treatment is not yet possible. In spite of this, with a symptomatic, individualized therapy by means of excision, low-dose irradiation and cytotoxic agents a 5-year survival of 90% was obtained for the patients. (5) Because of its rarity and multidisciplinary character, histiocytosis-X is a challenge to interdisciplinary and interregional cooperation. Though not being a malignoma in the strict sense, diagnosis, therapy, and in part prognosis are not essentially different from a malignant disease.

Adult

[Congenital arteriovenous fistula with an angioma. Therapeutic possibilities].

Arteriovenous fistulas associated with an angioma are characterized by a relatively fast growth. Therapy consists in operative removal of the entire angioma. This often means partial amputation of extremities. An embolization of the angioma, as in an observed patient can prevent further progression. A disfiguring operation can be delayed or possibly even avoided.

Adult

[Post-thrombotic axillary vein syndrome (Paget-von Schroetter syndrome)].

In acute thrombosis of the subclavian and axillar vein--known in the literature as Paget-von-Schroetter syndrome--skin can also be involved if no treatment is provided. The skin lesions resemble stasis dermatitis seen in chronic venous insufficiency of the lower extremity. The specific role of intima lesions of the subclavian vein caused by microtraumas is discussed because the Paget-von-Schroetter-syndrome is mainly seen in physically hard working men.

Aged

[Excessive allergy due to benzoic acid followed by anaphylactic shock. (author's transl)].

The case of a trained chemical worker highly sensitive to benzoic acid is described. He suffered from allergic reactions of increasing intensity while being constantly exposed to benzoic acid during work. After oral exposure to benzoic acid he suffered a severe anaphylactic shock and later on showed similar but milder reactions when eating food containing benzoic acid. No allergic reactions reoccurred avoiding every contact with benzoic acid especially observing a strict benzoic acid-free diet.

Adult

[Myoglobin increase during tocolysis (author's transl)].

The serum myoglobin level was performed before as well as two and four hours following the beginning of intravenous tocolysis in 22 pregnant patients who were treated with the betasympathicomimetic agent, hexoprenalin because of premature labour. In six of the patients a rise of 26--140% in myoglobin was observed in comparison with the basal level. One of the patients even produced a twenty-fold rise. The value of serum myoglobin determination in the diagnosis of myocardial necroses is discussed with respect to the literature and the presented material.

Adult