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Biomedical subjects

W Lehner

Publications and source records attributed to W Lehner.

6 recordsLinked to original sources
PubMed1990

[Use of a capacitive measuring mat for recording inter-fragment pressures and pressure distribution in ventral inter-corporal spondylodesis].

With respect to ventral interbody fusion, rates of pseudarthrosis of up to 30% are reported. With the aim of reducing this figure, the use of dorsal fixation systems to stabilise the fused spinal units is recommended by a number of authors. The aim of these osteosynthetic procedures is to elevate the interfragmentary compression between the ventral bone block and the adjacent vertebrae. In order to measure the pressure achievable, and its local distribution, an experimental investigation involving the use of a capacitive measuring mat has been designed. The system of capacitive measurement and its application to the spine is described. The simple mode of measurement and mechanical stability, combined with high accuracy, are the specific advantages of capacitive systems of measurement. Especially in the documentation of interfragmentary pressure and pressure distribution, capacitive measuring mats are superior to comparable systems.

Biomechanical Phenomena↗
PubMed1979

Establishment of carcinoma cell lines from larynx and submandibular gland.

For many techniques in the oncology of head and neck tumors large amounts of pure tumor cells are required. Although larynx and salivary gland tumors are common in man, no report exists on isolation and purification of tumor cells of which malignancy was proved. The present paper describes in vitro cultivation of living human malignant tumor cells from a larynx and a submandibular gland carcinoma. Carcinoma cells were freed from all non-tumor cells and cloned thus indicating that cultures contained only a single cell type. Transplantation of grown cells s.c. into athymic (nu/nu) mice induced rapidly growing tumors of which malignancy was demonstrated by histology.

Animals↗
PubMedDate not supplied

[Ventral compression spondylodesis using internal fixator instrumentation--a biomechanical study].

Pseudarthrosis is said to be a main complication in anterior interbody fusion. It is usually the result of an insufficient mechanical stability which hinders bony incorporation of intervertebral bone grafts. In order to improve stability dorsal transpedicular instrumentation should be carried out to achieve interfragmentary compression between bone block and adjacent vertebral endplate. Using human lumbar spine cadavers and a capacitive measuring mat an experimental study was completed to find out in which way an internal fixator has to be used to achieve this goal. The collected data showed that simple compression of the fixator by reducing the distance between the Schanz-screws did not produce sufficient interfragmentary compression. Preloading the fixator in kyphosis and compression in a second step improved the results significantly. Using this technique a compressive interbody fusion can be attained.

Adolescent↗