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W Leibl

Publications and source records attributed to W Leibl.

34 records · Page 2Linked to original sources

Spin-density distribution in the [FeO2]-complex. Electron spin resonance of myoglobin single crystals.

X-irradiated oxymyoglobin (MbO2) exhibits electron spin resonance (ESR) spectra at 77 K due to two distinct [FeO2]-centers formed by electron addition to the dioxygen. In single crystals with 17O and 57Fe isotope enrichment in the heme-ligand complex, the full set of spectral parameters is analyzed for one of the centers (gmax = 2.23, gint = 2.13, gmin = 1.97; HOmax = 2.66 mT, HOint = 1.61 mT, HOmin = 0.57 mT; HFe max = 1.62 mT, HFe int = 0.57 mT, HFe min = 0.49 mT) and the iron-dioxygen spin-density distribution and bonding geometry is derived. The g-tensor is evaluated for the second species at 77 K (gmax = 2.25, gint = 2.11, gmin = 1.95). Both centers transform into secondary species at 180 K for which the g-tensor elements are analyzed (gmax = 2.31, gint = 2.18, gmin = 1.93; gmax = 2.35, gint = 2.21, gmin = 1.91).

Crystallization↗

[Changes in gastric mucosa, liver and mesenteric vessels following bipolar electrocoagulation].

The implications of bipolar electrocoagulation with a modified probe (BICAP) were tested in rat gastric mucosa, liver tissue and mesenteric vessels. This was done during the coagulation and at different intervals, up to 14 days later, by intravital microscopy of the exposed organs. A histological treatment of the respective tissues ensued at the closing of each experiment. Applying a current of 25 watt and contact times lasting for 5 secs and longer, perfect tissue necrosis develops which has clean and straight edges. The extensions on the surface and into the depth of gastric mucosa match precisely the contact area with the instrument. In the deeper mucosal layers there is a fungiform spread of necrosis while in the liver it remains uniform and shows the same diameter as on the surface. As a late result and notwithstanding the confinement of the coagulation to the mucous membrane, a local peritonitis may develop. Within contractile vessels the action of bipolar coagulation stops the blood flow which is only irreversible, when the current and contact times are extended to bring about necrosis in neighbouring tissue. Within the microcirculation of the liver the blood flow is preserved up to the very boundary of the necrosis.

Animals↗

[Agammaglobulinemia and eosinophilic gastroenteritis].

The case is reported of a 34-year-old patient with diffuse eosinophilic gastroenteritis in connection with agammaglobulinaemia and B-cell defect. The syndrome was manifested by malabsorption, and gastrointestinal protein loss, complicated by temporary pyloric obstruction and duodenal ulceration. As in the case of sprue-like changes in the small intestinal mucosa, and nodular lymphoid hyperplasia, this diffuse eosinophilic gastroenteritis may be a reaction of the stomach and small intestine to immunological abnormalities.

Adult↗

[Experimental siderosis bulbi: an echographic-histological study (author's transl)].

In 20 eyes of 10 rabbits a siderosis was provoked by intravitreal injection of 0,1 ml of a 1% watery solution of Mohr's salt. The course of the following vitreous retraction was observed during 4 weeks by means of ultrasonography, and each echogram was compared with the corresponding histological finding. The results of these investigations show that by means of ultrasonography vitreous destruction or liquefaction can be ascertained and distinguished from an undulation, taught or funnel-shaped detachment of the posterior hyaloid membrane; in addition, this membrane and retinal detachments are well discernible by this method.

Animals↗

[The influence of the retina on the maturation of the testicles: an experimental study in rabbits (author's transl)].

In the present experimental study in rabbits the importance of the non-illuminated retina as a superior regulating centre for the maturation of the testicles is demonstrated. Involvement of the retinal maturation by an experimentally provoked total retinal detachment is followed by a cessation of the development of the testicles. The extent of this influence can be brought in evidence by means of the quotation of the fatty acids C20:4/C22:5 as well as on the hand of the histological findings.

Animals↗

[Pseudotumorous gout in a 34-year-old man].

We report the case history of a young man, who suffered from atypical gout. The most prominent clinical findings were several tumor-like tophi. One of these located close to the right knee joint and impeding the joint motion had to be surgically removed.

Adult↗