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Biomedical subjects

W Liu

Publications and source records attributed to W Liu.

At least 703 records · Page 39Linked to original sources

Treatment of acute exacerbation of chronic cor pulmonale with fei xin ling syrup.

30 cases of chronic cor pulmonale with acute exacerbation were treated with Fei Xin Ling Syrup compared with 30 similar cases treated with Western modern drugs as controls. The Chinese herbal drug modality was found to be superior to the administration of modern drugs in the control group in overall therapeutic effects, with regard to the symptoms of coughing, tachypnea, phlegm production, edema, and the prevention of heart and respiratory failure. Rheological studies in part of the patients also indicated that the Chinese herbal prescription improved the blood circulation.

Aged↗

[Effect of Helicobacter pylori on gastric epithelial apoptosis].

To investigate the mechanisms by which Helicobacter pylori (Hp) induces gastric mucosal damage, gastric epithelial apoptotic index (AI) of normal gastric mucosa and Hp positive gastritis before and after anti-Hp treatment was studied with the method of terminal transferase mediated dUTP nick end labeling. The results showed that AI in Hp positive gastritis was higher than that in normal mucosa (P < 0.001). After the eradication of Hp, AI fell significantly to the normal level (P < 0.001). AI in persisting Hp positive gastritis had no statistically significant decrease after the anti-Hp treatment. There was no correlation between AI and the severity of gastritis. These results indicated that Hp could induce gastric epithelial apoptosis, which may be an important mechanism involved in gastric mucosal damage.

Adult↗

[Preparation method of foamed aerosol for use in vagina].

The extraction of medicinal materials, compatibility of liquor and prescription of emulsion for use in vagina were observed. The result shows that through compound extraction, removal of tannic materials, decolorization and water precipitation, with propylene glycol and ethylene glycol as latent solvent and using lactic acid to adjust to pH4.5, a clarified solution can be obtained, and then with the help of Tween-spans emulisifying agent and propellant the stable emulsion is formed.

Administration, Intravaginal↗

[Epstein-Barr virus infection in midline malignant reticulosis].

OBJECTIVE: To observe the presence of Epstein-Barr virus (EBV) infection in a group of patients with midline malignant reticulosis (MMR). METHOD: DNA-RNA in situ hybridization was used to detect EBER and immunohistochemical staining was used to examine the expression of latent membrane protein (LMP) and immunophenotype of atypical lymphoid cells (ALCs) in 37 cases of MMR; polymerase chain reaction (PCR) was used to detect EBV-DNA in 15 cases. RESULTS: (1) ALCs were positive for EBER 1/2 in 31/37(83.8%) cases; EBV-DNA was detected in 12/15(77.8%) cases; LMP was expressed in some ALCs in 5/19(26.3%) cases. (2) ALCs in 20/37(54.1%) gave both positive reactions to CD3 and CD56 antigens. CONCLUSION: A higher percentage of EBV infection was detected in this group of MMR, its ALCs expressed not only T-cell markers, but also NK-associated antigen, CD56. The presence of EBV infection in different kinds of lymphoproliferative disorders is reviewed and discussed.

Adult↗

[Reconstruction of laryngotracheal stenosis: experience of twenty years].

In order to improve the curative effects of laryngotracheal stenosis, 261 patients treated for laryngotracheal stenosis during the last twenty years were retrospectively reviewed. Glottic reconstruction, fence-form laryngotracheal reconstruction and laryngotracheotomy with autogenous tissue or hydroxylapatite rings were selectively used for one-stage reconstruction. Our results demonstrated that among 261 patients, 9 failed in decannulation, 5 were lost for follow-up, 247 (94.6%) patients were successfully decannulated. Among 192 patients followed-up from 1 to 18 years, 4 had restenosis 3 years after operation, 3 were successfully retreated and 10 failed. 182 (94.7%) patients had stable airways. It is concluded that there was no fixed treatment for laryngotracheal stenosis. The choice of surgical procedure and grafting must be decided on the pathologic condition of the larynx and trachea. The advantages of fence-form laryngotracheal reconstruction are simple technique and good result. Reconstruction with combined bipedicled myocutaneous flap and costal cartilage or artificial materials are better for severe laryngotracheal stenosis and large tracheal defect. The usage of stent is important for laryngotracheal reconstraction.

Adolescent↗

[On the mechanism of hemilaryngeal fixation in pyriform sinus carcinoma and its clinical significance].

To approach the mechanism of hemilaryngeal fixation in pyriform sinus carcinoma (PSC), surgical specimens from total laryngectomy and partial hypopharyngectomy in 43 cases of pyriform sinus carcinoma were studied using organ subserial sections. Invasion of intralaryngeal muscles and the upper and outer aspects of arytenoid cartilage via paraglottic space was found to be the main cause of hemilaryngeal fixation in these cases. Presence of tumor on the medial wall of the pyriform sinus makes involvement of intralaryngeal structures easy, and thus is more frequently seen with hemilaryngeal fixation. Clinical T3 lesion of the sinus may infiltrate laryngeal cartilages and adjacent soft tissue to become pathologic T4 lesion. For PSC appearing hemilaryngeal fixation, total laryngectomy is safer to thoroughly remove cancer.

Adult↗

[Determination of maesopsin in shengdeng (Rhamnella gilgitica Mansf. et Melch) by HPLC].

A reversed-phase HPLC method was developed for the determination of maesopsin, a fliavonoid, in the xylem parts of the traditional Tibetan medicinal herb Shengdeng (Rhamnella gilgitica). An ODS column was used and the mobile phase was methanol-water (28:27) with 0.05 mol/L KH2PO4 (pH4). The detection wavelength was UV 290 nm. The recovery was 98.9% (RSD = 2.1%, n = 6) and the content of maesopsin in Shengdeng was 1.02% (RSD = 0.52%, n = 3).

Benzofurans↗

[Dual-energy separation imaging on an X-ray direct digital imaging system].

A method of dual-energy separation of bone and soft tissue images of chest based on an X-ray direct digital imaging system has been investigated. In this paper, the optimal thickness of the filter for high energy X-ray beam is discussed. An algorithm of correction of scattered radiation is employed before the separation algorithm. The separated images will be shown in the paper. The result shows that it is possible to use an ordinary broad spectral X-ray beam to acquire the dual-energy images for routine X-ray diagnosis.

Humans↗

[Application of ultrasound biomicroscopy in diagnosis of anterior segment vitreoretinal disorders].

PURPOSE: To investigate the diagnostic value of ultrasound biomicroscopy(UBM) in anterior segment vitreoretinal disorders(ASVD). METHODS: 60 eyes of 58 sequential patients were examined with UBM. The ultrasound biomicroscopic images were compared with the results of clinic examination, B-scan ultrasonography and the finding during surgery to evaluate the reliability of UBM for ASVD. RESULTS: UBM allows structural details of the conjunctiva, rectus muscle, sclera, uvea, retina and vitreous to be visualized at microscopic resolution in living eye. The area of UBM may cover from cornea to vitreous base, partially to the equator of eye. A variety of the changes of ASVD were imaged in 60 eyes, including retinal detachment in 43 eyes, retinal circumferential contraction in 29 eyes, retinal anterior displacement in 24 eyes, vitreous opacities or fibrosis in 57 eyes, ciliary orchoroidal detachment in 26 eyes, ciliary nonpigmented epithelial detachment in 6 eyes, proliferative tissue at the sclerotomy site in 9 eyes, retinal neoplasm in 2 eyes, ciliary cyst in 6 eyes, proliferation of peripheral silicone oil in 8 eyes, silicone oil emulsification in 7 eyes and vitreous foreign body in 2 eyes, respectively. CONCLUSIONS: Our studies showed the feasibility of UBM for ASVD not visible by current techniques UBM can be used for the diagnosis, differential diagnosis and the instructive treatments of ASVD.

Adult↗

[A method based on the theory of stochastic recursive identification for lossless compression of medical images].

This paper describes a method based on the theory of stochastic recursive identification for lossless compression of medical images detail. The performances of this method are compared with the existing method of DPCM through ten X-ray chest images. The experimental results clearly indicate that this method is very valid to realize lossless compression of medical images.

Electronic Data Processing↗

[Matched case control study for investigating of the association between psychosocial factors and TMJDS].

A 1:1 matched case control study was carried out in 81 cases with temporomandibular joint dysfunction syndrome (TMJDS) who came to a TMJ clinic of a tertiary dental centre for help and 81 controls without TMJDS to investigate the association between psychosocial factors and TMJDS. The results showed that anxiety and depression might be one of the risk factors of TMJDS. Trait anxiety and Eysenck's neuroticism might be the inherent personality factor of anxiety, and the later might be the basis of depression. Life events and social support might be the external factors of TMJDS.

Adolescent↗

[Thermoregulation under simulated weightlessness].

The effect of simulated weightlessness on thermoregulation was studied in 5 subjects. The experiment consisted of 3d baseline measurements, 7d head-down bed rest and 2d recovery. Circadian rhythm was assessed by continuous measurements of rectal temperature and skin temperature with 2h intervals. Heat Stress Protein 70 (HSP70) was measured by Western-blot Dot method and the facial surface temperature distribution was measured by HR-2 infrared thermography. The results showed that rectal temperature keeps the wake-sleep variation, but the circadian rhythm changed during bed rest, and the change of rectum temperature rhythm appeared mainly in the early-days of bed rest; HSP70 and facial surface temperature increased during bed rest.

Bed Rest↗

[Studies on sultamicillin hydrolysis].

Sultamicillin is an oral mutual pro-drug composed of double esters of formaldehyde hydrate in which one of the hydroxyl groups is esterified with ampicillin and the other with sulbactam. It is hydrolyzed fast in neutral or weakly alkaline condition. When hydrolyzed, it forms ampicillin and hydroxylmethyl sulbactam or sulbactam and hydroxylmethyl ampicillin by different routes. Usually, the former has priority as the two ester bonds have different activities. The ratio of ampicillin to sulbactam in the products is about 3:1. Both the hydroxylmethyl sulbactam and the hydroxylmethyl ampicillin can be further catalyzed by esterase to produce formaldehyde.

Ampicillin↗

[The antibechic, expectorant and antiasthmatic actions of Cynanchum komarovii].

The water and ethanol extracts of Lao Gua Tou (Cynanchum komarovii) is effective on relieving cough caused by the irritation of ammonnia water in mice. The extract can increase the secretion of repiratory tract and promote expectoration, also alleviate asthma induced by histamine and acetylcholing chloride in guinea pigs.

Animals↗

[An analysis of the infection state of hepatitis C virus in liver diseases].

UNLABELLED: The local state of hepatitis C virus infection was probed. METHOD: The markers of hepatitis viruses were tested by nested RT-PCR and ELISA. RESULTS: In the patients with transfusion history, the incidence of acute hepatitis C (60.53%) was higher than that of acute hepatitis B (10.53%, P<0.01). In the patients with acute hepatitis without transfusion, however, the percentage of type A (41.67%) and type B (30.56%) hepatitis were higher than that of type C hepatitis (4.17%, P<0.01). The incidences of acute and chronic posttransfusion hepatitis C and asymptomatic HCV-infected cases, respectively 60.53%, 20.34% and 29.17%, were higher than that of the cases without transfusion, which were 4.2%, 8.74% and 3.33% respectively (P<0.01-0.05). No matter whether the patients with chronic hepatitis, severe hepatitis, cirrhosis, hepatocellular carcinoma or asymptomatic had transfusion history or not the incidences of HBV infection in them were higher than that of HCV infection (P<0.01). CONCLUSION: Most of the source of HCV infection were from transfusion, but infective rate of HCV by way of non-transfusion was lower. Severe hepatitis, chronic hepatitis, cirrhosis and hepatocellular carcinoma in local area was mostly induced by HBV.

Adult↗

[Preliminary study on the arsenic trioxide-induced NB4 cell apoptosis and its molecular mechanisms].

OBJECTIVE: To illustrate the possible cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL). METHODS: APL cell line NB4 was used for in vitro studies. The effect of As2O3 on APL was studied by using flow cytometry, DNA electrophoresis, Narthern blotting and Western blotting. RESULTS: As2O3 induced NB4 cell apoptosis, while not inhibiting the growth and survival of two other leukemic cell lines (HL-60 and U937). Furthermore, As2O3 effectively down-regulated the expression of bcl-2 gene without changing the mRNA levels of other apoptosis-associated genes (including p53, c-myc, bax and bcl-XL). CONCLUSION: These might be one of the molecular mechanisms of As2O3 induced NB4 cell apoptosis.

Animals↗