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Biomedical subjects

W M McCormack

Publications and source records attributed to W M McCormack.

At least 145 records · Page 8Linked to original sources
PubMed1973

Isolation of Eikenella corrodens in a general hospital.

Eikenella corrodens is a small pleomorphic gram-negative bacillus which produces pitting on agar. From December 19, 1970, to December 2, 1971, E. corrodens (also known as HBI) was isolated from material submitted to the Diagnostic Bacteriology Laboratory of the Boston City Hospital from 72 patients (48 males, 24 females) ranging in age from 8 months to 92 years. The organism was recovered from sputum or bronchial washings in 46 instances, from throat or nasopharyngeal swabs in 11, from wounds in 8, from 2 human bites, and from 3 abscesses. It was isolated in pure culture from one of the human bites. Antibiotic susceptibility was measured for 26 strains against six antibiotics by using the inocula replicating method on heart infusion blood agar. E. corrodens was most susceptible to penicillin and ampicillin with 100% and 96% of strains inhibited by 1.65 mug of these antibiotics per ml, respectively. Eighty percent of the strains were inhibited by 3.125 mug of chloramphenicol per ml and 52% were inhibited by this amount of gentamicin. Resistance was greater for tetracycline and clindamycin.

Anti-Bacterial Agents↗
PubMed1972

A comparison of purging and multiple rectal swabs in the detection of inapparent cholera infections.

The relative effectiveness of daily rectal-swab cultures and cultures of purged stools in detecting inapparent infections of Vibrio cholerae were compared in family contacts of cholera patients. In one study of 187 contacts, a combination of purging by various methods plus 5 daily swabs detected 50 infections. Only 27 (54%) were detected by the purge alone, while 47 (94%) were detected by 5 daily rectal-swab cultures. In a second study of two groups of family contacts, purging on the first day did not appear to influence significantly the number of positive rectal-swab cultures obtained during the 4 subsequent days. The relative inefficiency of purging in detecting the inapparent infections among cholera contacts, as compared with its reported efficacy in the chronic convalescent carrier, probably reflects a basic difference in the pathogenesis and site of infection in these different conditions.

Adolescent↗