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W Maciejewski

Publications and source records attributed to W Maciejewski.

At least 19 recordsLinked to original sources
PubMed1996

[Tumor of the follicular infundibulum. Study of determining follicular differentiation].

Tumor of the follicular infundibulum is a rare proliferation of cells and its histogenesis or differentiation at the morphological level has been the subject of some controversy. In recent years cytokeratins have been recognized as important markers of epithelial differentiation, and of late new retrieval methods have meant it is possible to detect them in formalin-fixed and paraffin-embedded tissue. Four patients were studied, the ages ranging between the 2nd and 7th decade. The tumors were all located in the head and neck and in one case the lesion developed in a pre-existing sebaceous nevus. The morphological investigation revealed a flat, proliferation of polygonal, pale eosinophilic cells connected to epidermis or follicular infundibulum and with a centrally located nucleus. In addition, a few ductal structures resembling sebaceous ducts were seen and in one case a hair germ papilla and a follicular papilla was noted. Immunohistochemical investigations with antibodies against cytokeratins revealed differentiation comparable to that in the fetal follicular isthmus and, in one case, also differentiation in keeping with the fetal follicular infundibulum.

Adult↗
PubMed1995

Localized cicatricial pemphigoid of the Brunsting-Perry type with transition into disseminated cicatricial pemphigoid. Report of a case proved by preembedding immunogold electron microscopy.

BACKGROUND: In 1979, Provost described two patients with the clinical features of disseminated cicatricial pemphigoid for the first time. Until now, only four additional cases of disseminated cicatricial pemphigoid have been described. Existence of diagnosis of disseminated cicatricial pemphigoid has been discussed controversially because in four cases investigated by electron microscopy the blister formation was found below the lamina densa, which is indicative of an epidermolysis bullosa acquisita. OBSERVATION: A 78-year-old woman is presented with a generalized eruption of blisters leaving behind scars that developed after a 7-year-long history of mild circumscribed recurrent blisters and scarring eruptions that had been diagnosed previously as Brunsting-Perry type of cicatricial pemphigoid. Immunofluorescence antigen mapping disclosed the blister formation above the lamina densa. Electron and immunoelectron microscopy using a preembedding immunogold technique revealed blister formation and antibody binding within the lamina lucida, predominantly below the subbasal dense plate. CONCLUSIONS: The clinical features of disseminated blistering followed by scarring, the immunofluorescence antigen mapping, and the electron and immunoelectron microscopic findings in our case for the first time clearly prove the existence of a disseminated cicatricial pemphigoid.

Aged↗
PubMed1994

[Hipocratean pseudepigrapha].

Apart from translations of Persian letter (the first 9 letters from Pseudepigrapha) their critical analises are presented. A point is made that due to their character differing them from medical writings, Pseudepigrapha are an important complement in the research of the Hipocratean tradition.

Greek World↗
PubMed1993

[Localized cicatricial bullous pemphigoid of the Brunsting-Perry type].

Localized cicatricial pemphigoid of the Brunsting-Perry type is a very rare bullous condition, which has so far been reported in 51 cases. It is characterized by scarring blisters confined to the head, scalp and neck. Diagnosis can be difficult because of the discrete skin lesions, often repeatedly false-negative direct immunofluorescence, and the absence of circulating antibodies. We report on a 87-year-old male patient with the typical clinical feature of a cicatricial pemphigoid of the Brunsting-Perry type and give a review of the 51 cases published in the world literature.

Aged↗
PubMed1992

[Not Available].

Explore the source record for details and available documents.

Greece↗
PubMed1990

Persistent atrioventricular block in Lyme borreliosis.

Cardiac manifestations are reported in 0.3%-4.0% of European patients with Borrelia burgdorferi (B.b.) infection. Usually symptoms disappear within 6 weeks. We report a case with persistent impairment of atrioventricular (AV) conduction. Diagnosis was confirmed by demonstration of IgM antibodies and increase of IgG antibody titers against B.b. in serum, by isolation of the spirochete from skin biopsy material and by the typical clinical combination of erythema migrans, Bannwarth syndrome (meningoradiculitis), and complete heart block. Despite immediate antibiotic therapy with ceftriaxone, first degree AV block and second degree block Wenckebach with atrial pacing at 100 beats/minute persisted for 2 years. We conclude, that Lyme carditis can cause long-standing or irreversible AV conduction defects despite adequate and early antimicrobial therapy.

Adult↗
PubMed1989

[Unusual manifestations of Lyme borreliosis. A contribution to the clinical spectrum of this disease group].

Since the discovery that EM (erythema migrans), ACA (acrodermatitis chronica atrophicans) and BL (borrelial lymphocytoma) have an infectious etiology, these syndromes have been receiving particular attention. This report describes four patients whose dermatological symptoms did not at first indicate borreliosis. In all four cases serological antibody tests proved that they were caused by Borrelia burgdorferi. In two of these cases these findings were confirmed by bacterial cultures. The unusual skin symptoms, i.e. multiple disseminated erythema, erysipelas-like manifestations, swelling and discoloration of the eyelids and lichenoid papules, extend the known clinical spectrum of cutaneous borreliosis in Europe.

Adult↗
PubMed1986

[Proliferating epidermal cysts].

While proliferating trichilemmal cysts are a well-known entity, so far there have been no reports on the proliferating processes of epidermal cysts. Two patients with multiple proliferating cysts are presented. Histologically, there was a well-developed stratum granulosum in the wall of the most cysts, and the cavity contained orthokeratotic horny material. The possible pathogenetic mechanisms of cyst formation are discussed.

Adult↗
PubMed1984

[Localized bullous pemphigoid].

A 73-year-old women developed tight blisters exclusively on the legs. The histological and immunological examinations substantiated the diagnosis of localized pemphigoid. The disease had a chronic course and responded well to treatment with prednisolone.

Aged↗
PubMed1980

Annular erythema as an unusual manifestation of chronic disseminated lupus erythematosus.

Numerous annular erythematous lesions developed in a 47-year-old woman, involving most of the integument. Thorough clinical, histopathologic, and immunopathologic investigations confirmed the diagnosis of lupus erythematosus. Unusual clinical, histologic, and immunofluorescence microscopy patterns emerged during the course of the disease, which was resistant to treatment.

Biopsy↗
PubMed1979

Immunoelectron-microscopical localization of in vivo-bound complement C3 in bullous pemphigoid with the use of the peroxidase-antiperoxidase multistep technique.

In vivo-bound complement C3 in bullous pemphigoid was precisely localized by means of the peroxidase-antiperoxidase multistep technique. In the nonbullous lesions peroxidase deposits filled the lamina lucida completely, i.e., the space between lamina densa and the cell membranes of the basal cells. In developed bullae, the reaction product was located both on the lamina densa and on the surface of separated keratinocytes. These findings may indicate that antigen components in bullous pemphigoid are localized almost exclusively within the ground substance which fills the lamina lucida and covers the surface of the basal cells.

Aged↗
PubMed1979

[Extramammary Paget's disease].

A case of extensive extramammary Paget's disease in the scrotum and penis is demonstrated. The disease started a few years before as eczema-like lesions. No underlying carcinoma was found. The surgical excision resulted in a good cosmetic effect.

Aged↗
PubMed1979

Lupus erythematosus panniculitis(profoundus).

A 39 year-old man developed on trunk, buttock and thighs scaling, atrophic, erythematous lesions which in some places became infiltrated and ulcerated. The clinical, histopathological and immunlogical picture corresponded with the diagnosis of discoid lupus erythematosus. In sites of infiltrations and necrosis, however, histological features of panniculitis with proliferative and inflammatory changes of deep vessels could be seen. The direct immunofluorescence of uninvolved skin showed deposits of IgM and C3 at the dermal-epidermal junction and within the vessel walls. The patient responded promptly to treatment with chloroquine.

Adult↗
PubMed1979

[An unusual clinical form of pemphigus vulgaris].

A 36-year-old woman developed bullous skin lesions which clinically seemed most likely to be dermatitis herpetiformis or bullous pemphigoid. However, histological examinations as well as immunofluorescence and electron microscopic observations substantiated the diagnosis of pemphigus vulgaris.

Adult↗
PubMed1979

[Lichen purpuricus (lichen aureus)].

A 14-year old boy developed lesions, which clinically and histopathologically corresponded to the rare condition known under the term of lichen purpuricus seu aureus. The disease can be classified close to purpura pigmentosa progressiva.

Adolescent↗
PubMed1978

[Erythema elevatum diutinum. I. Electron microscopy of a case with extracellular cholesterosis (author's transl)].

1. A typical case of Erythema elevatum diutinum (E.e.d.) with extracellular cholesterosis is described clinically and histologically in a 48-year-old woman. The disease had a course of 15 years. 2. Electron microscopy confirmed the histological and immunfluorescent findings of leucocytoclastic vasculitis. In older lesions, histiocytes/macrophages predominate. Intra- and extracellular lipid depositions showed a variety of ultrastructural characteristics which differed from electron microscopical findings described in other disorders associated with lipid deposition. 3. The findings are in accordance with the hypothesis that the primary event in E.e.d. is a special type of chronic leukocytoclastic vasculitis. Subsequently, the damage of the vessel walls and focal necrosis may lead to secondary lipid deposition.

Cholesterol↗