PubMed Health⌕ Search

Biomedical subjects

W McMillan

Publications and source records attributed to W McMillan.

9 recordsLinked to original sources
PubMed1989

What's new in otolaryngology?

The author discusses advances in the practice of otolaryngology, focusing on diagnosis and surgical techniques. New requirements for physicians are also discussed.

Humans↗
PubMed1989

Otolaryngologists stress education.

The author, an otolaryngologist in Ottumwa and president of the Iowa Academy of Otolaryngology, discusses that organization's goals and the current practice environment for otolaryngologists.

Humans↗
PubMed1985

Midazolam and diazepam compared as sedatives for outpatient surgery under local analgesia.

Patients who had given their informed consent took part in a study to compare the sedative properties of the new benzodiazepine, midazolam, with diazepam. The drugs were administered intravenously and the quality of sedation, profoundness of amnesia, and rate of recovery were examined. Both drugs provided good-quality sedation, with midazolam producing a significantly greater degree of amnesia. Psychomotor tests used to assess recovery showed that patient performance following exposure to either drug had returned to normal 2 hours postsedation. However, patients who had received diazepam were drowsier later in the day and during the night following sedation than those who received midazolam. The implications of these findings are discussed.

Adolescent↗
PubMed1985

A monoclonal antibody against basal cells of human epidermis. Potential use in the diagnosis of cervical neoplasia.

A murine monoclonal antibody was generated against human skin cells obtained from psoriatic plaques. The antibody, called VM-2, recognizes an epitope expressed on the basal cell layer of human skin and other epithelia. VM-2 also binds to cultured cells from a variety of human carcinomas including HeLa cervical carcinoma, A-431 vulvar carcinoma, A-549 lung alveolar carcinoma, and SCL-1 skin squamous cell carcinoma cells. In several primary human cell lines, including fibroblasts, endothelial cells, and cells from the hematopoietic lineage, the antigenic site recognized by VM-2 could not be detected. The cellular antigen when immunoprecipitated by VM-2 from both normal and transformed cells appears to be proteins of approximately 100,000 and 120,000 mol weight. In frozen sections from human tumor-containing tissues, VM-2 labels skin, cervical, and lung squamous carcinoma cells, as well as skin basal carcinoma cells. Malignant cells present in exfoliative smears from epidermoid invasive neoplasias of the cervix are also selectively recognized by VM-2 in distinction to normal squamous cervical cells. VM-2 is thus directed against an antigen associated with neoplastic cells when applied in selected sites of exfoliative cytology. This monoclonal antibody represents a new reagent that should prove useful in the diagnosis of cervical neoplasia.

Antibodies, Monoclonal↗
PubMedDate not supplied

Nursing auxiliaries: developing services for elderly people.

The establishment of a project to support and develop the role of nursing auxiliaries working with elderly people is described. Organised and run by two clinical facilitators, a variety of research methods, including interviews and non-participant observation of clinical practice, were used to establish baseline data. The interview information showed that there was general dissatisfaction among trained and untrained staff about the auxiliaries' roles, and clinical practice assessment of 206 auxiliaries demonstrated deficiencies in their communication, lifting and infection control techniques. Individual ward development and management of change plans were then set up and operated.

Aged↗