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Biomedical subjects

W Meese

Publications and source records attributed to W Meese.

At least 19 recordsLinked to original sources
PubMed1987

[Tumor differentiation by multivariate discriminant procedures in CT absorption analyses].

An attempt is made to utilise so-called absorption analyses in cranial CT for further differentiation of the diagnosis of the various types of space-occupying growths. Characteristic distributions are shown for specific "regions of interest" in meningiomas, glioblastomas and cerebral abscesses before and after contrast medium injections. Clear criteria can be formulated for the differentiation of glioblastoma and cerebral abscess using multivariate discriminance analyses.

Brain Abscess↗
PubMed1978

The diagnostic value of CT for radiotherapy of cerebral tumors.

The paper deals with CT followup studies on 73 patients with cerebral tumors who received radiotherapy. The value of CT for the indication of radiotherapy, for followup therapy and for the demonstration of therapeutic success are discussed. Since the cerebral tumors become visualized by means of CT in their entire extent and can be differentiated from perifocal edema, the question arises whether radiotherapy should consist of higher doses in the future. It is also suggested that the "clinical malignancy" may be used to compare the behavior of cerebral tumors when there is no exact histological classification. The possible histopathological effects of radiotherapy (edema, necrosis) and their demonstration by CT are discussed.

Adult↗
PubMed1978

The role of computed tomography in the diagnosis of brain tumors in infants and children.

CT has considerably facilitated the diagnosis of intracranial tumors, especially in infants and children. The authors review their experience with a series of 260 children with proven brain tumors. In most cases CT is so conclusive that other diagnostic techniques are no longer often needed. Pneumoencephalography in particular has largely been replaced by CT in recent years in the authors' departments, and the frequency of central ventriculography with contrast material has decreased substantially. Particular diagnostic difficulties with regard to tumors near to or within the caudal brain stem, some posterior fossa tumors, small vermian tumors, and tumors of the cerebral hemispheres are discussed.

Age Factors↗
PubMed1978

Axial transverse computerized tomography in 73 glioblastomas.

Among 2,600 patients, examined by computerized tomography, 404 had brain tumours, which were gliomas in 150 cases. There were 73 glioblastomas. Examination was performed according to Ambrose's method using an intravenous injection of 1 ml 60% contrast medium per kg body weight. Thus 98% of all gliomas could be demonstrated. Glioblastomas are shown in three different forms: an annular type (55%), a nodular type (18%), and a combined type (27%). Perifocal oedema is found in 88% of glioblastomas. The oedema most frequently belongs to grade II or III. Differentialdiagnosis of gliomas, abscess, metastases and other tumours with central necrosis are discussed.

Astrocytoma↗
PubMed1977

Computed tomography in the diagnosis and differential diagnosis of glioblastomas. A qualitative study of 295 cases.

The CT patterns of 295 glioblastomas examined with pre- and postcontrast scans using an EMI scanner Mark I (Matrix 160/160) have been reviewed and compared with the CT appearances of other brain tumors, metastases and abscesses. There is a great variety of CT patterns with glioblastomas. However, a garland-shaped CT appearance, representing a subgroup of ring-shaped lesions, seems to be most typical for glioblastomas since it was observed in 19% of ring-shaped glioblastomas but in only one out of 172 metastases and in no case of an astrocytoma grade II or an abscess in our series. The initial CT diagnosis, based on the CT finding, the patient's history and the clinical data, was correct in 69.8% of the glioblastomas, 41 recurrent glioblastomas included. In 12% of the cases the presence of a glioblastoma was within differential diagnosis. These results lead to the conclusion that in many cases additional diagnostic methods, such as serial scintigraphy and/or cerebral angiography, are required for a reliable differential diagnosis.

Astrocytoma↗
PubMed1977

Computed tomography or orbital lesions. A cooperative study of 210 cases.

Computed tomography (CT) has given us a new method for examining the orbit and its contents. The technique of examination is described, and the indications for the application of computed tomography in ophthalmology are considered: suspected orbital tumors, unilateral exophthalmos, pareses of the ocular muscles, traumatic lesions and malformations in the region of the orbit. The findings in 210 cases of orbital lesions examined in this study are reported and the differential diagnosis is discussed. Considerable improvement and greater accuracy in diagnosis have been achieved in the field of ophthalmology by using computed tomography. Early tumor visualization is possible without risk or discomfort to the patient.

Abscess↗
PubMed1977

[Computer tomography in intracranial tumors. A cooperative study of 1658 neoplasms (author's transl)].

This paper decribes the results of the CT teams of the University Clinics Berlin, Mainz and Munich. 1658 patients with cerebral tumors have been examined so far (EMI Scanner Mark I, Matrix 160/160) revealing a diagnostic accuracy of 98.4%. The findings of various kinds of tumors (306 glioblastomas, 255 astrocytomas and oligodendrogliomas, 248 meningiomas, 212 metastases, 200 pituitary adenomas and craniopharyngeomas) are discussed and illustrated by typical images. Differential diagnostic problems and the importance of additional neuroradiological procedures are discussed.

Adolescent↗
PubMed1976

[Transverse axial computerized tomography (EMI scan): value and indications (author's transl)].

The results of transverse axial computerized tomography in EMI scan (transverse CAT) in 2 000 examinations are reviewed. The method was shown to enlarge significantly the diagnostic possibilities in cerebral disease. A correct identification of intracranial tumour was made in 98% of 250 cases. Cerebral haemorrhage, infarction and contusional oedema could be differentiated. Various forms and extensions of cerebral oedema were visualized as never before. Postoperative changes and the course of vascular disease, tumour or hydrocephalus after shunt were demonstrated at an early stage. The indications for pneumo-encephalography have been reduced to a few very special situations. On the other hand, angiography is still of decisive value in vascular cerebral disease and should be performed before surgery in case of space-occupying lesions.

Brain↗
PubMed1976

[Differential diagnosis of stroke in computer tomography].

Computertomography permits an early diagnosis of acute intracerebral hemorrhage a few hours after onset of symptoms. Embolic or thrombotic infarcts may be detected only after 2 to 3 days. Late manifestations of ischemic infarcts are unequivocal when confined to the circulation area of a cerebral artery. They must, however, be differentiated from small gliomas with edema, while in cerebral hemorrhage the differential diagnosis must consider bleeding from tumors and vascular malformations.

Brain Neoplasms↗
PubMed1976

[CT findings in chronic subdural hematomas (author's transl)].

CT findings of 46 patients with operatively confirmed chronic subdural hematomas are reviewed. The analysis of the EMI scans resulted in three different types of CT findings. Type 1 is characterized by decreased attenuation of the hematoma contents compared to brain tissue. The hematoma is visualized as a lens-shaped low density area between the skull and the surface of the brain. Type 2 apart from low density areas contains zones of increased attenuation due to recent bleeding into a watery chronic subdural hematoma. In many cases sedimentation causes a well-defined horizontal borderline between the thin fluid parts in the anterior portion and the blood debris in the posterior portion of the hematoma sac. Type 3 shows the same average absorption values as normal brain tissue, a direct visualization is not possible. However , the presence of a midline displacement in combination with ventricular compression and absence of a circumscript lesion even after contrast enhancement, allows the diagnosis of a unilateral chronic subdural hematoma in these cases too. Bilateral chronic subdural hematomas may cause considerable diagnostic difficulties if only one or none of the hematomas is visualized. A relatively small midline displacement points to a second bleeding on the opposite side. Most frequent were hematomas of type 1 (37%), type 2 and 3 could be observed in 30,5% resp. 32,5% of cases respectively.

Adolescent↗
PubMed1976

[Axial computer tomography of the brain].

Computertized tomography of the brain, developed by Hounsfield - has decisively altered neuroradiologic procedures. Without the need of contrast media, cerebral structures (ventricles cisternes, sulci and physiological calcifications) and pathologic lesions (infarctions, hemorrhage, edema, tumors and malformations) may be visualized. Tumors can be diagnosed in 95 to 99% by this method. Tumors of the midline structures and of the posterior fossa are more easily detected than by conventional methods. In head injuries epidural and subdural hematoma, contusional edema and hemorrhage may be differentiated. Hydrocephalus externus and internus can be shown by computertized tomography. Probably computertized tomography will become the most frequently applied neuroradiological method in the future.

Brain↗
PubMed1976

[Cranial axial computerized tomography in children (author's transl)].

This report on computerized tomography in 400 children confirms the high diagnostic value of the new method in neuropediatrics. 31 brain tumours were diagnosed in children. Tumors present themselves as lesions of latered density compared to that of brain matter. Intravenous injection of contrast media increases the density of various lesions as tumors, angiomas, acute infarctions and abscess. Infarctions are low density lesions whereas hemorrhage is a high density lesion and both are thus safely differentiated. Edema may be visualized in the vicinity of tumours in brain injuries and in encephalitis. The normal ventricular system, hydrocephalus, cerebral malformations and subdural hygroma are easily demonstrated. Diseases of the orbits may also be detected.

Brain Abscess↗
PubMed1975

Experiences with the echo midliner in children.

Three hundred eighty-five children were examined with the Midliner echoencephalography unit. In examinations termed adequate, correct interpretations were made in 94.6% of healthy children versus 78% ill children. The incidence of adequate examinations increases with the child's age, but 58% of children with hydrocephalus had inadequate examinations, regardless of age. For the measurement of the infantile ventricle system the midliner is not appropriate.

Brain Diseases↗