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Biomedical subjects

W Mende

Publications and source records attributed to W Mende.

At least 19 recordsLinked to original sources
PubMed1997

[Evaluating work capacity after myocardial infarct].

Work resumption of patients after myocardial infarction is primarily dependent on left-ventricular function, stress-related ischemia and rhythm-disturbances, additionally the general physical and psychological state play an important role. -The basic examination includes not only the history and physical examination, but also resting ECG, ECG exercise testing, 2-dimensional echocardiogramm and Holter-ECG. Additionally, stress-echocardiogramm, nuclear exercise testing and invasive procedures can be necessary. It is possible to estimate the work-capacity of the patient by classifying the ECG testing and by regarding further details of the disease. The return-to-work-rate does not only depend on the severity of a CHD, but also on the age, education, social class, high physical activity during work, job related satisfaction, family situation and available suitable jobs on the labor market.

Adult↗
PubMed1980

[Development of dendrite structures on CA 1 hippocampal pyramidal neurons of rat dependent on their stratification with and without non-specific experimental influence].

In this paper pyramidal neurons of the CA 1-region of the hippocampus of the rat were investigated by means of GOLGI-methods. Animals were used in the stages of age E 20, P 5, P 10, P 15, P 20 added by 15 days old rats reared in darkness or under the influence of constant noise of 80 dB. In these cells the dendritic structure and the amount of visible spines were morphometrically estimated and evaluated by statistical procedures. The neurons of the normal ontogenetic range increase in dendritic length already from P 5 under particular emphasis on Stratum oriens and Stratum radiatum. The spines express a rapid development in the Strata oriens, radiatum, lacunosum beginning in Str. lacunosum at P 5 and in the others at P 10. This fact indicates certain systems of afferents to arrive at several times or to posess different importance to the layors. Because of the fact, that the Str. moleculare, which receives only extrahippocampal afferents, remains significantly behind the other layers regarding the development of spines, it is to be assumed, that the intrahippocampal afferents exhibit a higher importance to the development of CA 1-pyramids. The rearing in darkness causes a significantly decreased development of spines within all the layers, so that the amount of visible spines nearly remains at the values of P 10. Constant noise however causes only a significantly enforced development of spines in the Strata oriens, radiatum, molecular e.g. in layers receiving extrahippocampal afferents. An approach to stage P 20 takes place only at Str. moleculare possibly depending on its large extrahippocampal input. As an expression of specificity a pericaryon-dendrite-factor can be assumed responsible for the election of afferent fibres and the development of spines especially at the animals reared in darkness. The reactivity of the neurons is exhibited by the relative independence of the Strata lacunosum and oriens during the ontogenetic development and of the Stratum moleculare at rats reared under the influence of constant noise.

Animals↗
PubMed1976

[Forensic psychiatric aspects of sterilization].

How great the risk is that important and long-lasting psychic disturbances persist after sterilization cannot be forecast with certainty, even today. Increased susceptibility to abnormal psychic reactions and developments after sterilization is to be contemplated with certain personalities with overconscientious, asthenic or depressive traits. It is usually a matter of internal conflict situations at the level of self-esteem which, however, depend not only on the initial personality, but to a large extent are repeatedly reactualized through the behavior and reaction of the persons in the environment, so that finally mental developments arise which reach into the abnormal. This risk must be included in the calculation when making the indication and requires particular attention, because the legal effectiveness of the consent to sterilization is also dependent on the completeness of the advice on the consequences of this surgical operation.

Female↗
PubMedDate not supplied

Developmental aspects of infant's cry melody and formants.

This paper deals with the analysis of cry melodies (time variations of the fundamental frequency) as well as vocal tract resonance frequencies (formants) from infant cry signals. The increase of complexity of cry melodies is a good indicator for neuro-muscular maturation as well as for the evaluation of pre-speech development. The variation of formant frequencies allows an estimation of articulatory activity during pre-speech vocalization. Subjects are three pairs of healthy identical twins (monocygozity determined by DNA-fingerprint). Spontaneous cries of these six children were recorded at different ages: 8th-9th week, 15th-17th week and 23rd-24th week. Analysis of 136 cry melodies and intensity contours was made using KAY-CSL 4300/MDVP. For formant estimation a spectral parametric technique was applied, which was based on autoregressive models (Digital spectral analysis with applications, 1987) whose order is adaptively estimated on subsequent signal frames by means of a new method (Med. Eng. Phys. 20 (1998) 432; Utras. Med. Biol. 21 (1995) 793). Cry melodies exhibited an increasing complexity during the observation period. Beginning with the second observation period (15th-17th week) an increasing coupling and tuning between melody and resonance frequencies was observed, which was interpreted as "intentional" articulatory activity. Possible applications are in cry diagnosis as well as in the evaluation of pre-speech development.

Crying↗