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Biomedical subjects

W O Thomson

Publications and source records attributed to W O Thomson.

10 recordsLinked to original sources

Colorectal carcinoma: presentation and management in a general hospital.

Over a five year period (1981-1986), 44 consecutive patients who presented with colorectal carcinoma were studied prospectively. Forty one (93%) patients underwent surgery, 11 as an emergency. The operative mortality was 7.3% and the wound infection rate was 12.2%. Of the original 44 patients only 18 (41%) are still alive at the end of the study period. The presentation, treatment and prognosis of patients with colorectal cancer in a general hospital are discussed.

Aged↗

A patient with six primary carcinomata.

We report a patient who developed six different primary carcinomata over a period of 3 years. These were of sigmoid colon, left breast, left kidney, right breast and two basal cell carcinomata of her face. These were all excised and she remains well with no apparent metastases 5 years after her initial presentation. Although patients with multiple tumours are uncommon, recognition of such an occurrence is important to avoid attributing symptoms to metastases from a previously diagnosed tumour. Sequential primary tumours may be amenable to treatment.

Adenocarcinoma↗

Neurofibrosarcoma of the duodenum in von Recklinghausen's disease.

The clinical features and surgical management of 2 patients with neurofibrosacroma of the duodenum in association with von Recklinghausen's disease are described. The tumours were excised and the resulting duodenal defects closed satisfactorily using the jejunal serosal patch technique. Three such neurofibrosarcomas reported previously in English are reviewed.

Adult↗

Is duodenitis a dyspeptic myth?

In 502 fibreoptic oesophagogastroduodenoscopies performed over 30 months, 14 cases (2.8%) of symptomatic duodenitis without an associated duodenal ulcer were diagnosed. Follow up (1 to 3-5 years) including repeat endoscopy and double-contrast barium meal showed that duodenal ulcers later developed in 6 patients. All have undergone surgery. A further 2 patients continued to complain of dyspepsis, and repeat endoscopy showed duodenitis, confirmed by conventional light microscopy (haematoxylin and eosin). The remaining patients are symptom-free. Repeat endoscopy and histological examination were either normal or showed mild inflammation of the duodenal mucosa. These findings suggest that duodenitis can cause symptoms and may be part of the pathophysiological spectrum of duodenal ulceration rather than a separate disease. It may represent both the production and healing phases of duodenal ulceration.

Adolescent↗

The clinical significance of pneumatosis cystoides intestinalis: a report of 5 cases.

Pneumatosis cystoides intestinalis is an uncommon condition characterized by the presence of gas within the wall of the bowel. In most cases the clinical course is benign and may well be self-limiting, while in others the appearance of pneumatosis may indicate the presence of bowel ischaemia and necessitate emergency laparotomy. This paper describes 5 cases which demonstrate some of the difficulties in diagnosis and management and the improvement which can result from clinical awareness of the condition.

Adult↗