PubMed Health⌕ Search

Biomedical subjects

W Oberwittler

Publications and source records attributed to W Oberwittler.

At least 19 recordsLinked to original sources
PubMed1982

Electrocardiographic findings in cystometric procedures.

Twenty-eight elderly patients, mostly with minor electrocardiographic abnormalities, underwent cystometry and simultaneous recording of the electrocardiogram in order to assess the influence of intravesical pressure elevation with regard to electrocardiographic changes. During cystometry intra-atrial, atrioventricular and ventricular conducting time remained unaffected, while the cardiac rate showed a moderate but significant increase without any serious impairment of cardiac function. It is concluded that slow filling without overdistension of the bladder can be considered safe even in elderly patients with cardiovascular problems.

Aged↗
PubMed1980

[HDL cholesterol: clinical and pathobiochemical aspects (author's transl)].

The determination of high density lipoprotein (HDL)-cholesterol in patients with mild hypercholesterolemia (240-300 mg/dl) allows one to distinguish between hyperbetalipoproteinemia (= high atherogenic risk) and hyperalphalipoproteinemia (= low atherogenic risk). In addition, analysis of HDL-cholesterol is of value in the prediction and early recognition of coronary heart disease, particularly in combination with known risk factors (hypertriglyceridemia, adipositas, smoking). This prognostic value of HDL-cholesterol is a result of its negative correlation to coronary heart disease which has been recognized in epidemiologic and clinical studies. The study of Tangier disease (analphalipoproteinemia) and tissue culture experiments will provide opportunities for the further elucidation of the role of HDL in atherogenesis.

Apoproteins↗
PubMed1978

[Correlations between age, risk factors for arteriosclerosis and endocrine functions (author's transl)].

In 377 males and 528 female factory workers basal serum levels of glucose, neutralfat, cholesterol, Na, K, Ca and LH, FSH, TSH, Prolactin, GH, Insulin, total corticoids and testosteron were determined. Mean values and standard deviations as well as correlations between mean basal hormone levels and other serum parameters, blood pressure and relative body weight (Broca Index) and partial correlations excluding age and relative body weight were calculated. Basal serum levels of LH, FSH, GH and prolactin show age and sex dependent secretion patterns. In men serum insulin-, GH- and total corticoid levels correlate positive significant with glucose and cholesterol levels, relative body weight and blood pressure, which possibly shows, that these hormones may play a role in the development of degenerative heart and blood vessel diseases. Testosteron levels and parameters of fat metabolism, relative body weight and diastolic blood pressure correlate negative significant. Obviously testosteron has a protective effect against arterioslcerotic lesions. In women insulin and GH do not have the same importance as in men. Prolactin serum and cholesterol level correlate negative significant. In postmenopausal women LH and FSH serum levels correlate positive significant with glucose and cholesterol levels, blood pressure and relative body weight, the so called risk factors for arteriosclerosis.

Adult↗
PubMed1977

[Free amino-acids of the plasma in atherosclerotic patients (author's transl)].

18 free amino-acids have been valuated in a group of patients recovering from myocardial infarction dating more than one year back and in another group of healthy active athlets. In the group of the ill persons the mean values of the following amino-acids were significantly higher: Arginine, asparagine-acid, phenylalanine, valine, lysine, serine, threonine, leucine, proline and tyrosine. While in the group of the healthy persons the following amino - acids proved to have significantly higher values: alpha -- aminobutter-acid, glycine and cystine. No significant differences between the mean values of both groups were to be found of the following amino - acids: Alanine, methionine, ornithine, isoleucine and histidine. In the group of the patients correlations of the free amino acids to both serumlipids and blood -- glucose could be calculated with significant results in a certain number of amino-acids. The results may suppose that the changes in the metabolism of atherosclerotic patients do not only effect the lipids and carbohydrates, but as well the free amino-acids.

Adult↗
PubMed1976

[Investigations on LH and FSH serum levels before and after application of synthetic LH-releasing-hormone in healthy men of different age].

50 male healthy volunteers of different age had measurements of plasma luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Basal levels of LH and FSH as well as maximal release of both hormones after i.v. application of 25 mug of synthetical LH-releasing hormone have been done. Results demonstrate an increasing reserve capacity of LH and FSH with age. FSH/LH ratio is altered in favor of FSH with duration of life. Sensitivity of gonadotropin producing cells of adenohypophysis to LH-releasing hormone is diminished in old age that can be recognized from a diminution of the relative rise of serum LH and FSH after LH-RH application. Correlations and partial correlations of absolute and relative body weight with age and basal LH and FSH serum levels demonstrate that age and not body weight plays a main part for increasing gonadotropin serum values. Causative responsibility for the increased LH serum concentrations is a decrease of testosterone production with age. Data obtained in this study and reports presented in literature give no convincing explanation for the increase of FSH serum levels with age.

Adolescent↗