Some memories of Frederic Eugene Basil Foley.
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Biomedical subjects
Publications and source records attributed to W P Mulvaney.
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Renal calculi weighing in excess of 100 gm. are rare, since most stones cause arrest of renal function before they reach giant proportions. We report a rare case of a 100 per cent struvite calculus weighing 698 gm., associated with transitional cell carcinoma of the ipsilaterl renal pelvis. A summary of the large calculi reported in the recent literature is included.
A case of bilateral renal vein infiltration and thrombosis secondary to malignant lymphoma is presented. Although the kidney frequently is known to be involved by metastatic lymphoma, uremia is a rare terminal complication. The etiology and diagnosis of this disorder are discussed. We believe that it is important to recognize renal vein thrombosis in such patients so that treatment with radiation and/or chemotherapy may restore renal function.
Deep venous thrombosis is a potential complication of transurethral resection of the prostate. We evaluated 150 paients undergoing transurethral resection of the prostate for benign and malignant disease to determine the postoperative incidence of deep vein thrombosis, using phleborheography as the instrument of detection. Phleborheography is an accurate, inexpensive, non-invasive method that uses low pressure transducers to detect volumetric changes in the lower extremity through recording cuffs. A 4.6 per cent incidence of deep venous thrombosis was detected by this technique. At the time this complication was discovered no patient exhibited clinical signs of thrombophlebitis, which reinforces the belief that clinical diagnosis alone is not a reliable screening technique for deep venous thrombosis. Anticoagulant therapy appears to be effective and safe in the treatment of this postoperative complication.
Phenazopyridine hydrochloride is an effective oral urinary analgesic commonly used for the treatment of irritative lower urinary tract conditions. We believe that stones already present may serve as a nidus for significant deposition of phenazopyridine hydrochloride.
Acetylcysteine seems to be beneficial in treating cystinuric stone-forming patients. It probably is effective in reducing cysteine to cystine disulfide, which is more soluble. Six brief case reports demonstrate its use and its lack of toxicity. The results merit a larger clinical trial.
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