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Biomedical subjects

W Philipp

Publications and source records attributed to W Philipp.

42 records · Page 3Linked to original sources
PubMed1986

[Studies of the penetrating ability of fosfomycin into the aqueous humor and vitreous body of the eye].

Fosfomycin is an antibiotic with a new simple chemical structure and a broad spectrum of antibacterial activity, especially against staphylococci. In the study reported here, the penetration of fosfomycin into the aqueous humor and vitreous body was investigated after intravenous infusion of 4 and 8 g. The highest average concentration approximately 2 hours after administration was 28.3 micrograms/ml after the 4 g dose and 52 micrograms/ml after the 8 g dose. Both the 4 g and 8 g doses thus produced aqueous humor levels exceeding the minimum inhibitory concentrations required for most gram-positive and gram-negative organisms commonly responsible for bacterial endophthalmitis, including strains of pseudomonas aeruginosa. Extremely high aqueous humor levels of fosfomycin were observed in two patients with inflamed eyes because of a change in the blood-aqueous barrier.

Aqueous Humor↗
PubMed1985

[Carotinoid deposits in the retina].

In this case report a 55-year-old Turkish patient with polymorphous light eruption, who has been treated with high doses of beta-carotene and canthaxanthin for more than 6 years is described. The examination of the fundus showed dense, glistening bright yellow crystalline deposits around the maculae. The only functional impairment that could be detected was a slight decrease in visual acuity and dark adaptation.

Canthaxanthin↗
PubMed1985

[The occurrence of Salmonellae in organic fertilizer].

Out of 24 samples of organic and organic-chemical fertilizers which were bought in retail stores ("Bio-Fertilizers") in 25% salmonellas and in 12.5% Clostridium perfringens were isolated. In each of the fertilizers, from which these pathogens were cultivated, products from animal origin were part of the ingredients. In the majority of the cases these were animal fecal residues but also blood meal and horn shavings. The epidemiological importance of these findings is discussed. It is appealed to the legislature to bring the ordinance on fertilizers to bear which demands "rendering to hygienically safe products". It is further necessary to lay down relevant executive orders for the hygienic control of the fertilizers and the supervision of the production plants. This is especially important in the context of the aim to check salmonellosis of man and animals.

Animals↗
PubMed1983

[Communicable disease problems of sewage sludge].

Sewage sludge is a concentrate of pathogenic agents which survived the sewage purification processes. Such hazardous sludges therefore should be disinfected prior to their utilization in agriculture. Necessary technologies for each size of treatment plant are on the market available. The new ordinance for the agricultural utilization of sewage sludge which comes into force the 1 April 1983 meets to a large extent the expectations of hygienists.

Agriculture↗
PubMed1981

[Survival of salmonellas and ascaris eggs during sludge utilization in forestry (author's transl)].

Salmonella senftenberg survived in sewage sludge after a single application in summer in experimental plots of 11 different forest stands between 424 and 820 days. After application of infected sludge in winter the survival times were between 104 and 350 days. Salmonelles adsorbed to germ carriers located on or below the sludge layers survived for a shorter time than those germs which were suspended into the sludge. Ascaris eggs survived not longer than between 78 and 107 days. It is therefore recommended to prohibit the utilization of infectious sewage sludges in forests and at their edges as it is handled in Switzerland. If this cannot be achieved the permission for utilization of sludge in forests should only be given if the sludge is tilled into the soil.

Agriculture↗