Influence of Eraldin on some indices of atherogenesis.
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Adult↗
Biomedical subjects
W Piwowarska
Publications and source records attributed to W Piwowarska.
[Functioning of the transplanted heart].
There are significant differences between functioning of transplanted and healthy hearts. Assessment of such a heart and therapeutic possibilities in heart recipients require understanding of these differences. Vegetative denervation of heart increases its sensitivity to the circulation humoral substances, especially catecholamines. In the early postoperative period, filling pressures of the right and left ventricle are elevated. An increase in pulmonary resistance accompany noted pulmonary hypertension, leading subsequently to the right ventricular failure and mitral valve insufficiency. Normalization of these disorders begins in the majority of cases about 4 months following heart transplantation. A type of immunosuppression has an important effect on circulatory hemodynamics. A systemic blood hypertension is a frequent complication of immunosuppression with cyclosporine A in heart recipients. Heart contraction frequency is usually higher in heart recipients than that in control group, and its resting mean value is 90 beats per minute. Moreover, a mild circadian changes in this frequency by about 20% is noted in heart recipients. Cardiac arrhythmias following heart transplantation are associated with the degree of denervated heart transplant to arrhythmia is rather improbable. Cardiac drugs acting with mediation of vegetation system have no effect on the transplanted heart. Heart transplant is fully capable to maintain proper body functioning.
Arrhythmias, Cardiac↗
[Significance of echocardiographic examination in controlling the function of the transplanted heart].
Echocardiographic examination helps to assess the structure and functioning of transplanted heart. In early post-transplantation period, the right cardiac ventricle is usually enlarged in ECHO records, and pulmonary pressure is elevated. Both size and functioning of the left ventricle are usually normal in both early and late periods following transplantation. Endomyocardial biopsy remains a basic diagnostic technique in transplant rejection. Echocardiography is a valuable non-invasive technique enabling to diagnose moderate to severe transplant rejection. The most valuable for the diagnosis of transplanted heart rejection are changes in the left ventricle diastolic indices (prolongation of relaxation time and half-life of pressures gradient across mitral valve). Remote prognosis in heart recipients depends on the progressing left ventricle dysfunction, mainly diastolic, and vasculopathy developing in the late postoperative period.
Cardiomegaly↗