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W Prinz

Publications and source records attributed to W Prinz.

10 recordsLinked to original sources

[Follow-up and management of patients with incomplete cone biopsies for dysplasias (author's transl)].

Report of 86 cone biopsies for dysplasias of the cervix. In 11 of these cases the cone biopsy did not show a clearly dysplasia free margin. These patients were followed from 1 to 6 years without further treatment and none showed a suspicious or positive pap smear. In young patients who desire further pregnancies it appears to be justified to follow without further treatment even after incomplete cone biopsies for dysplasia. Two patients with complete removal of the dysplasia and a normal margin in the cone biopsy later showed positive pap smears. The importance of further follow-up of the cases is stressed.

Aftercare

Cinnabarinate synthase from baboon (Papio ursinus) liver. Identity with catalase.

The enzyme chinnabarinate synthase was purified from the nuclei of baboon liver. Two purified fractions were obtained that exhibited a typical haem protein absorption spectrum; a probable identity with catalase was demonstrated. It was confirmed that catalase in the presence of Mn2+ produces cinnabarinate from 3-hydroxyanthranilate. Doubt is expressed on the existence of a distinct cinnabarinate synthase enzyme.

3-Hydroxyanthranilic Acid

The effect of ascorbic acid supplementation on some parameters of the human immunological defence system.

We have investigated the effect of ascorbic acid (vitamin C) supplementation on some parameters of the human immune defence system in a group of 25 healthy, male university students. The subjects ingested 1 g ascorbic acid per day for a period of 75 days. Serum levels of IgA, IgG, IgM, C-3 complement component, cortisol and transcortin were measured before and after the ascorbic acid course. Corresponding measurements were performed on a control group of 20 healthy, male university students receiving no extra-dietary vitamin C. Our results showed that ascorbic acid supplementation caused a statistically significant increase in the serum levels of IgA, IgM and C-3 complement. Our study does not permit of conclusions regarding the mechanisms of action of ascorbic acid.

Adolescent

Clinical investigation of a very low dosage oral contraceptive combination: 0-75 mg lynestrenol and 0-0375 mg ethinyl oestradiol.

A trial was carried out in 3 clinics to test the efficacy of and cycle control obtained with a very low dosage oral contraceptive combination of lynesternol (0.75 mg) and ethinyl oestradiol (0.0375 mg). A total of 134 healthy, fertile women, ages ranging from under 19 years to over 40 years, participated and completed 1144 treatment cycles. No pregnancies occurred. Then length of the treatment cycle compared to the cycle length before treatment was unchanged in 79.3% of cases. Withdrawal bleeding occurred in 93.1% of all treatment cycles, and in 78.9% of cases the duration of the withdrawal bleeding corresponded to that of the bleeding before treatment. The proportion of irregular bleeding in the first treatment cycle was 51.4% but by the 12th treatment cycle this was reduced to 12.5%. Side-effects, when they did occur, were very slight; existing complaints clearly decreased during the treatment.

Adolescent