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Biomedical subjects

W Proesmans

Publications and source records attributed to W Proesmans.

At least 109 records · Page 6Linked to original sources
PubMed1983

Urinary excretion of immunoreactive prostaglandin F2 alpha in healthy children and adults.

The 24-hours urinary excretion of immunoreactive prostaglandin F2 alpha (U-iPGF2 alpha) in normal children on a free diet was not significantly different in 30 boys (aged 3-15 years; geometric mean 589 ng/24 h) compared to 27 girls (aged 4-14 years; mean 473 ng/24 h). In both sexes this excretion rose with age until adolescence where it reached a plateau. In normal adults the men had significantly higher (p less than 0.001) excretions of U-iPGF2 alpha than the women; also body weight and urinary creatinine excretion were higher in men (p less than 0.001). In the children, as well as in the total population, U-iPGF2 alpha correlated best with body weight (r = 0.44 and r = 0.48 respectively; p less than 0.001) and the urinary creatinine excretion (r = 0.53 and 0.57 respectively; p less than 0.001); both body weight and urinary creatinine excretion are reflections of total body development. After the correction for urinary creatinine excretion or for body weight, the sex difference in the adult U-iPGF2 alpha totally disappeared.

Adolescent↗
PubMed1982

Abnormal prostacyclin metabolism in the hemolytic uremic syndrome: equivocal effect of prostacyclin infusions.

In a child with the hemolytic uremic syndrome, plasma 6 keto-prostaglandin F1 alpha levels remained undetectable throughout the acute phase of the disease. The patient's plasma failed to stimulate prostacyclin production by "exhausted" rat aorta rings. In vitro study of the patient's vessels indicated that they retained the capacity to synthesize prostacyclin from exogenous arachidonic acid but that their endogenous arachidonic acid stores were either depleted or non-available. The response to repeated infusion of exogenous prostacyclin was equivocal, suggesting that abnormal prostacyclin metabolism in the hemolytic uremic syndrome may not be the only factor in its pathogenesis.

Child, Preschool↗
PubMed1982

[Sonography of perirenal hematoma after percutaneous renal biopsy in children].

Gray scale ultrasonography was used to evaluate the incidence of renal or perirenal hematoma in children after percutaneous renal biopsy. On a total of 57 infants and children, we found perirenal hematoma in 10 cases or 16%. In an additional patient with macroscopic hematuria, ultrasound revealed pelvic obstruction due to clot formation. In this study the clinical findings and hematocrit were not really contributive in the detection of hematoma, making ultrasound the method of choice to monitor post biopsy complications.

Adolescent↗
PubMed1982

Autosomal dominant polycystic kidney disease in the neonatal period: association with a cerebral arteriovenous malformation.

Two brothers with the neonatal presentation of dominant polycystic kidney disease are reported. The first infant died shortly after birth; autopsy revealed polycystic kidneys. The second infant had two markedly enlarged kidneys at birth. Intravenous pyelography at the age of 10 days showed typical images as observed in the recessive form of polycystic kidney disease. Kidney biopsy showed cystic dilation involving all parts of the nephron; the liver biopsy did not show any abnormality. Severe arterial hypertension was a major problem in the first six months of life. At the age of 3 and 5 years, respectively, the patient developed intracerebral hemorrhage, which was due to a complex intracerebral arteriovenous malformation. At the age of 8 years the boy had chronic renal failure and spastic quadriplegia. Previously unsuspected polycystic kidneys were found in the father during the family study.

Angiography↗
PubMed1982

Ultrasonography for assessment of bleeding after percutaneous renal biopsy in children.

Ultrasonography has been used to assess renal bleeding after percutaneous renal biopsy in 57 infants and children. A perirenal hematoma was found in 10 patients i.e. an incidence of 16 per cent. An additional patient with heavy hematuria and temporary obstruction of the pelvis due to clot formation had an enlarged kidney and pelvicalyceal dilatation on ultrasound examination. We did not find a correlation between the clinical findings, the fall in hematocrit and the presence of a hematoma. Ultrasound can be regarded as the method of choice for monitoring renal bleeding in children who have undergone kidney biopsy.

Adolescent↗
PubMed1981

The haemolytic uraemic syndrome in childhood: a study of the long-term prognosis.

From January 1970 to June 1976, 45 children with the haemolytic uraemic syndrome were admitted to our department. They all received heparin in addition to supportive therapy. For the last ten patients heparin was given with dipyridamole (Persantin). Three children died in the acute stage of the illness giving an acute fatality rate of 6.6%. A fourth patients immediately needed chronic haemodialysis. In the other 41 patients, kidney function only partially recovered in two; they subsequently developed terminal renal insufficiency after 18 months and four years, respectively. The remaining 39 children have been regularly followed for three to eight years. None has been lost to follow-up. With only one exception, they all have shown a favourable evolution with negative urinalysis, normal blood pressure, and an endogenous creatinine clearance within the normal range for age.

Adolescent↗
PubMed1981

Recurrent acute renal failure due to nonaccidental poisoning with glafenin in a child.

A 7-year-old boy experienced recurrent attacks of acute renal failure over an 18 month period. Each attack was accompanied by a fluorescent yellow discoloration of his urine. Laboratory data and the kidney biopsy were consistent with acute tubulo-interstitial nephritis. Repeated contacts with the boy in a play setting and thorough toxicologic examination of his urine finally led to the conclusion that the mother systematically poisoned her child with glafenin. The clinical and experimental literature on glafenin-related disease is reviewed. This is the first report of glafenin intoxication in a child. This is also the first case of kidney disease as an expression of child abuse.

Acute Kidney Injury↗
PubMed1980

Pre-operative and post-operative evaluation of the rectal bladder.

Five Heitz-Boyer-Hovelacque operations in children were reviewed in which particular attention was paid to pre-operative examinations, including electromanometry (EMM) and post-operative evaluation of continence, functional result and renal function. In our limited experience the rectal bladder operation is a good procedure in selected cases; it produces satisfactory continence and maintains renal function.

Adolescent↗
PubMed1980

The complement system in hemolytic-uremic syndrome in childhood.

A dynamic estimation of the complement system was obtained by immunochemical estimation of C3, C4, C5, C1q, C3b + C3c, C3d, Ba in children with hemolytic-uremic syndrome. The presence of increased breakdown products of C3 (C3b + C3c, C3d) and of factor B (Ba) suggests an activation of the complement system possibly by the alternative pathway. No definite explanation for these complement abnormalities can be given.

Child↗